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Amyloid β-based therapy for Alzheimer’s disease: challenges, successes and future
Signal Transduction and Targeted Therapy, 2023Weihong Song
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The amyloid state and its association with protein misfolding diseases
Nature Reviews Molecular Cell Biology, 2014Tuomas P J Knowles +2 more
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Expression of the amyloid beta-protein precursor gene.
Advances in neurology, 1990D, Goldgaber, D E, Schmechel
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A new era for understanding amyloid structures and disease
Nature Reviews Molecular Cell Biology, 2018Matthew G Iadanza +2 more
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The Alzheimer disease-associated amyloid beta protein precursor gene and familial Alzheimer disease.
Progress in clinical and biological research, 1991The application of recombinant DNA techniques to AD and DS pathogenesis have provided the molecular biological reagents necessary to delineate the crucial events in the neurodegenerative process in these disorders. Critical issues which remain to be solved include: which form of APP gives rise to beta amyloid deposits and from what cells is it derived?
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The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics
Science, 2002John Hardy
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