Results 231 to 240 of about 288,605 (343)
Nanostructure and Collagen‐Stimulating Activity of Cationic Pentapeptide Lipopeptides
The self‐assembly in aqueous solutions, cytocompatibility and collagen production of lipopeptide C16–KTTKS (C16: hexadecyl) and a variant with arginine substitution for lysine, C16–RTTRS, are compared. ABSTRACT The self‐assembly in aqueous solutions, cytocompatibility, and collagen production of lipopeptide C16–KTTKS and a variant with arginine ...
Lucas R. de Mello +3 more
wiley +1 more source
To What Extent is Anfinsen's Thermodynamic Hypothesis Consistent With the Formation and Polymorphism of Amyloid Fibrils? [PDF]
Jiang YX, Eisenberg DS.
europepmc +1 more source
The formation of mono‐, dual‐, and triple‐species biofilms by L. monocytogenes, S. aureus, and E. coli was characterized by cell growth, metabolic activity, staining, and microscopy. Their resistance to a commercial disinfectant (NaOCl) and natural agents such as vinegar and lactic acid was evaluated.
Viviana Švarcová +6 more
wiley +1 more source
Protocol for structural analysis of amyloid fibrils using hydrogen-deuterium exchange mass spectrometry. [PDF]
Meng Q, Han Y, Zhou H, He Z.
europepmc +1 more source
ABSTRACT Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a fatal neurodegenerative disease primarily affecting motor neurons. Two key protein inclusions found in lower motor neurons serve as neuropathological hallmarks of the disease in human tissue: the TDP43‐positive inclusion and the cystatin C‐positive Bunina body.
Sarah M. Granger +5 more
wiley +1 more source
Cryo-EM structure of renal AL amyloid fibrils from a patient with λ1 light chain amyloidosis. [PDF]
Yu C +5 more
europepmc +1 more source
QBP1 Peptide as a Potential Anti‐Amyloidogenic Therapy for Type 2 Diabetes: An In Vitro Study
The anti‐amyloidogenic peptide QBP1 effectively halts human islet amyloid polypeptide (hIAPP) aggregation, preventing the formation of toxic β‐structured intermediates. Through a combination of biophysical assays, molecular dynamics, and cell‐based studies, QBP1 is shown to preserve β‐cell viability and metabolic homeostasis, positioning it as a ...
María M. Tejero‐Ojeda +8 more
wiley +1 more source
Abstract INTRODUCTION Pathological tau aggregates are key therapeutic targets in Alzheimer's disease (AD), but current approaches face limitations including poor intracellular penetration, lack of selectivity for aggregated over physiological tau, or reliance on invasive administration.
Nicolas Preitner +19 more
wiley +1 more source
The Reconstruction of Sesame Protein-Derived Amyloid Fibrils Alleviates the Gastric Digestion Instability of β-Carotene Nanoparticles. [PDF]
Zhang L +6 more
europepmc +1 more source
Abstract INTRODUCTION Recent epidemiological datasets have associated viral encephalitis exposure (i.e., viral‐induced neuroinflammation) with increased risk of Alzheimer's disease (AD) and dementia, highlighting the need to uncover how it may impact AD neuropathology.
Dominic Ibarra Javonillo +10 more
wiley +1 more source

