Results 221 to 230 of about 288,605 (343)

Structural characterization of atrial natriuretic peptide amyloid fibrils from patients with atrial fibrillation. [PDF]

Nat Commun
Broggini L, Piccoli M, Chaves-Sanjuan A, Bonnet DMV, Cirillo F, Visentin C, Sonzini F, Signorelli P, Lavota I, Milazzo M, Nonnis S, Menicanti L, Ciconte G, Pappone C, Anastasia L, Ricagno S.   +15 more
europepmc   +2 more sources

Mechanism of Self-Assembly of the Gonadropin Releasing Hormone Antagonist Teverelix into Amyloid Fibrils. [PDF]

Mol Pharm
Li X, Serpell LC, Bukrinski JT, Boutignon F, MacLean CM, Jackson SE.   +5 more
europepmc   +1 more source

Design, Synthesis, and Biological Evaluation of Chiral Urea and Thiourea Derivatives as Multitarget‐Directed Anti‐Alzheimer Agents

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT A series of novel chiral urea and thiourea compounds were designed as multitarget‐directed ligands for Alzheimer's disease and evaluated against hAChE, hBChE, and hMAO‐B, with exploratory assessment of HSD10. These chiral compounds were synthesized and fully characterized, and their enantiopurity was confirmed via HPLC.
Sule Erol Gunal, Senel Teke Tuncel, İlke Demir, İpek Baysal, Gökçen Telli, Safiye Sag Erdem, Gulberk Ucar, Michaela Hanzlova, Kamil Musilek, İlknur Dogan, Nesrin Gokhan Kelekci   +10 more
wiley   +1 more source

Micro‐ and Nanostructured Materials in Edible Coatings for the Preservation of Fruits and Vegetables

eFood, Volume 7, Issue 4, August 2026.
Graphical representation of micro‐ and nanostructured materials in edible coatings for the preservation of fruits and vegetables. ABSTRACT Edible coatings based on advanced nanostructured materials have emerged as effective strategies for extending the shelf life and maintaining the quality of fresh fruits and vegetables.
Carlos Méndez‐Durazno, Katherine Vaca‐Escobar, Fernanda Landeta‐Constante, Santiago Guerrero‐Jaramillo, Milton Villacís‐García, Patricio J. Espinoza‐Montero   +5 more
wiley   +1 more source

Alzheimer's Protection by PLCγ2 Compacts Plaques, Redistributes Microglia, and Protects Synapses in AppNL‐G‐F Mice

Glia, Volume 74, Issue 8, August 2026.
The Alzheimer's disease protective PLCG2 P522R variant protects against amyloid‐induced synapse loss independently of amyloid load, promotes increased plaque compaction, and is associated with enhanced microglial engagement with diffuse amyloid. ABSTRACT The Alzheimer's disease protective P522R PLCG2 coding variant (rs72824905) is downstream of TREM2 ...
Ryan J. Bevan, Emily Maguire, Eilish Mackinnon, Elisa Salis, Thomas Phillips, Elena Simonazzi, Marieta Vassileva, Nicholas D. Allen, Julie Williams, Philip R. Taylor   +9 more
wiley   +1 more source

Low-frequency Raman spectra of amyloid fibrils. [PDF]

J Chem Phys
Harper M, Dumi A, Upadhyay S, Workman RJ, Nelson D, Nudurupati U, Ou Y, Punihaole D.   +7 more
europepmc   +1 more source

Plasma Membrane Remodeling During Microglial Activation: A Hypothesis Linking Microglial Shape and Lipid Droplet Formation

Glia, Volume 74, Issue 8, August 2026.
Microglial morphology changes in response to damage by Aβ and aging result in significant reductions in cell surface area. Transcriptomic analyses suggest that fatty acid synthesis and triacylglycerol formation drive redistribution of surface membrane into intracellular lipid droplets.
G. William Rebeck, Giorgi Shautidze, Jordy Sepulveda, Gracie S. Healey, Priyanka S. Narayan   +4 more
wiley   +1 more source

Nanoparticles with Ampholytic Surfaces for Binding and Disintegration of Amyloid Fibrils. [PDF]

ACS Cent Sci
Mandal S, Nguyen MD, Jana NR, Lee TR.
europepmc   +1 more source

Immunoglobulin binding protein (BiP) forms two types of dimers

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Immunoglobulin binding protein (BiP) is a chaperone protein that plays crucial roles in protein folding and transport by binding unfolded proteins in the substrate binding domain (SBD), an interaction allosterically linked to the nucleotide occupancy of the nucleotide binding domain (NBD).
Karina New, Miguel I. A. Lagos‐Espinoza, Nathalie Casanova‐Morales, Roi Asor, John William Young, Zahra Alavi, Christian A. M. Wilson   +6 more
wiley   +1 more source

Effects of Treatment Methods on the Formation, Structure, and Functional Properties of Soy Protein Amyloid Fibrils. [PDF]

Foods
Zhang Q, Deng Y, Lu Y, Han L, Ma Q, Guo L, Fan F.   +6 more
europepmc   +1 more source