Results 201 to 210 of about 160,241 (252)

Flagella‐Mediated Biofilm Formation and 3D Swarming Drive Virulence in the Honey Bee Pathogen Paenibacillus larvae

Environmental Microbiology, Volume 28, Issue 11, November 2026.
The flagella of the bacterial pathogen Paenibacillus larvae, the etiological agent of American foulbrood in honey bees, were characterized and identified as virulence factors. These cellular appendages play key roles in biofilm formation and 3D swarming, two multicellular behaviours of P. larvae that contribute to pathogenesis.
Josefine Göbel, Anne Fünfhaus, Elke Genersch   +2 more
wiley   +1 more source

Biofilm Engineering for Efficient Substrate‐Enzyme Interactions to Enhance Enzymatic PET Degradation

Microbial Biotechnology, Volume 19, Issue 11, November 2026.
Engineered curli biofilms localize FAST‐PETase at the PET surface through SpyTag/SpyCatcher‐mediated immobilization, enhancing substrate‐enzyme contact during interfacial plastic depolymerization. This biofilm‐confined strategy improves PET film degradation, providing a proof‐of‐concept framework for biofilm‐assisted plastic biotransformation ...
Xinyu Zhou, Xinyu Zhou, Lilin Feng, Ren Wei, Ulrich Schwaneberg, Lars M. Blank, Anming Xu, Weiliang Dong, Min Jiang   +8 more
wiley   +1 more source

Human brain matters: Navigating the neuropathology of COVID‐19

Brain Pathology, Volume 36, Issue 6, November 2026.
Severe COVID‐19 is associated with vascular dysregulation and chronic neuroinflammation, leading to axonal injury and neurodegeneration. In long COVID or PASC, persistent alterations in neuroimaging and biofluid biomarkers reflect ongoing neuronal damage and neuroinflammation, contributing to long‐term neurological symptoms including fatigue, cognitive
Juliana M. Nieuwland, Angelica Scaramuzza, Marianna Bugiani, Wilma D. J. van de Berg, Jinte Middeldorp   +4 more
wiley   +1 more source

Comments to the “Letter to the Editor” for the manuscript titled “Increased expression of inflammasome signaling genes and proteins in selective brain regions in the intermediate stage of Alzheimer's disease”

Brain Pathology, Volume 36, Issue 6, November 2026.
Beta amyloid diffuse plaques, neurofibrillary tangles and neuritic plaques, are increased in densities at the intermediate stage of Alzheimer's neuropathological change. These pathological changes releasing Pathogen‐Associated Molecular Patterns (PAMPs) and Damage‐Associated Molecular Patterns (DAMPs).
Juan Pablo de Rivero Vaccari, David A. Davis, Andrew P. Sawaya, Susanna P. Garamszegi, Xiaoyan Sun, Ayled Barreda, Helen M. Bramlett, Sakir Humayun Gultekin, W. Dalton Dietrich, Robert W. Keane, Regina T. Vontell   +10 more
wiley   +1 more source

Light Chain Monoclonal Gammopathy of Undetermined Significance: Diagnosis, Biology, and Clinical Management

European Journal of Haematology, Volume 117, Issue 5, Page 1159-1167, November 2026.
ABSTRACT Light chain monoclonal gammopathy of undetermined significance (LC‐MGUS) is defined by an abnormal serum free light chain ratio and elevated involved light chain in the absence of a detectable immunoglobulin heavy chain on immunofixation and of end‐organ damage attributable to a plasma cell disorder.
Sigurður Yngvi Kristinsson, Thórir Einarsson Long, Sigrún Thorsteinsdóttir   +2 more
wiley   +1 more source

Phospholipid Monolayers and Vesicular Membranes Show Only Minor Structural Changes After Interaction With α$\alpha$‐Synuclein at Low and Physiological Concentrations

ChemPhysChem, Volume 27, Issue 20, 28 October 2026.
The interaction of α$\alpha$‐synuclein with lipid membranes in the synapse is intensively discussed in view of pathologies of neurodegeneration. By X‐ray diffraction from monolayer, lipid vesicles, and synaptic vesicles at different α$\alpha$‐synuclein concentrations, structural changes of the membrane can be probed in response to the interaction.
András Major, Eva von Campenhausen, Riko Hilger, Hendrik Bruns, Titus Czajka, Diego Pontoni, Martin Rosenthal, Gerard Aguilar Pérez, Christian Hoffmann, Mohammed Al‐Azzani, Tiago F. Outeiro, Dragomir Milovanovic, Tim Salditt   +12 more
wiley   +1 more source

Early‐Onset Wild‐Type Transthyretin Amyloidosis Polyneuropathy

Muscle &Nerve, Volume 74, Issue 5, Page 1471-1475, November 2026.
Chafic Karam, Kaylee Baker, Sami Khella, Brian Drachman, Pranav Chandrashekar, MacLean Nasrallah, Shunsuke Koga, Janice Pieretti   +7 more
wiley   +1 more source

Amyloid fibrils in urine.

The Western journal of medicine, 1978
M E, Titford, B S, Bull
openaire   +1 more source

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Inhibition of Amyloid Fibril Growth and Dissolution of Amyloid Fibrils by Curcumin–Gold Nanoparticles

Chemistry - A European Journal, 2014
AbstractInhibition of amyloid fibrillation and clearance of amyloid fibrils/plaques are essential for the prevention and treatment of various neurodegenerative disorders involving protein aggregation. Herein, we report curcumin‐functionalized gold nanoparticles (Au‐curcumin) of hydrodynamic diameter 10–25 nm, which serve to inhibit amyloid fibrillation
Nikhil R Jana, Amit Ranjan Maity, Nihar Ranjan Jana   +2 more
exaly   +3 more sources

Structures for amyloid fibrils

The FEBS Journal, 2005
Alzheimer's disease and Creutzfeldt–Jakob disease are the best‐known examples of a group of diseases known as the amyloidoses. They are characterized by the extracellular deposition of toxic, insoluble amyloid fibrils. Knowledge of the structure of these fibrils is essential for understanding the process of pathology of the amyloidoses and for the ...
O Sumner, Makin, Louise C, Serpell
openaire   +2 more sources