Results 241 to 250 of about 288,605 (343)

Amyloid exacerbates tau and alpha‐synuclein pathologies, behavioral impairments, and neuroinflammation in a mixed dementia model

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Neurodegenerative diseases often involve overlapping alpha‐synuclein (asyn), amyloid beta, and tau proteinopathies, yet the mechanisms, impact, and directionality of their interactions remain unclear. METHODS We induced brain‐wide neuronal asyn/tau pathologies via viral expression of wild‐type asyn, mutant asynE46K, mutant ...
Benjamin E. Rabichow, Lacey Nixon, Lauren E. Tallant, Katelin A. Gibson, David G. Nascari, J. Hudson Barnett, Nashali Massa, John D. Fryer   +7 more
wiley   +1 more source

Dual Hydrophilic-Hydrophobic Core Architecture in Soy Glycinin Amyloid Fibrils Revealed by Cryo-EM. [PDF]

Adv Sci (Weinh)
Li S, Li S, Cheng Y, Fang Y, Cao Q, Cao Y.   +5 more
europepmc   +1 more source

Plasma‐based neurobiological protein biomarkers as predictors of dementia progression: Insights from longitudinal aging study in India – Diagnostic assessment of dementia

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract BACKGROUND Major neurocognitive disorder (MNCD) represents a critical public health crisis. From the two waves of the Longitudinal Aging Study in India‐Diagnostic Assessment of Dementia, we investigated the predictive power of longitudinal alterations in plasma proteins to predict the progression from mild cognitive impairment (MCI) to MNCD in
Rashmita Pradhan, Masroor Anwar, Abhijith R. Rao, Ashish Datt Upadhyay, Abhishek Gupta, Abhinay Kumar Singh, Aparajit Ballav Dey, Sharmistha Dey   +7 more
wiley   +1 more source

Amyloid fibrils of the myelin basic protein are an integral component of myelin in the vertebrate brain. [PDF]

Sci Rep
Sysoev EI, Shenfeld AA, Belashova TA, Valina AA, Zadorsky SP, Galkin AP.   +5 more
europepmc   +1 more source

Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research

BioFactors, Volume 52, Issue 4, July/August 2026.
This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen, Thomas Roeder, Gerald Rimbach   +2 more
wiley   +1 more source

Correction to "Single-Molecule Orientation Imaging Reveals the Nano-Architecture of Amyloid Fibrils Undergoing Growth and Decay". [PDF]

Nano Lett
Sun B, Ding T, Zhou W, Porter TS, Lew MD.   +4 more
europepmc   +1 more source

3D structure of Alzheimer's amyloid-β(1–42) fibrils

, 2005
Thorsten Lührs, C. Ritter, M. Adrian, Dominique Riek-Loher, B. Bohrmann, H. Döbeli, D. Schubert, R. Riek   +7 more
semanticscholar   +1 more source

Structure of the cross-β spine of amyloid-like fibrils

Nature, 2005
R. Nelson, M. Sawaya, M. Balbirnie, A. Madsen, C. Riekel, R. Grothe, D. Eisenberg   +6 more
semanticscholar   +1 more source

Systemic Amyloidosis With Probable Cardiac Involvement: Diagnostic Approach in a Resource‐Limited Setting: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
Histopathological examination of an abdominal fat pad core needle biopsy demonstrating Congo red–positive amyloid deposition, confirming systemic amyloidosis. Representative photomicrographs illustrate characteristic amyloid deposits at low‐ and high‐power magnification.
Malegna Temesgen Garuma, Yonatan Debebe Regassa, Sifessa Dessalegn Demshasha   +2 more
wiley   +1 more source

Advances in the Neurotoxic Mechanisms of Acrylamide and Multitarget Intervention Strategies of Natural Products

Food Frontiers, Volume 7, Issue 4, July 2026.
This review summarizes recent advances in acrylamide neurotoxicity mechanisms and highlights the multitarget neuroprotective effects of diverse natural products while also addressing current challenges and future translational research directions.
Wen Du, Yifan Zhao, Li Dong, Chen Ma, Xiaosong Hu, Daotong Li, Fang Chen, Yinghua Luo   +7 more
wiley   +1 more source