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Mt Sinai J Med, 2012 As amyloid neuropathies have benefited from recent major progress, this review is timely and relevant.The main recent articles on amyloid neuropathy cover its description, methods for diagnosis and therapies. Varied clinical presentations are described in transthyretin (TTR)-familial amyloidosis with polyneuropathy (FAP) and light chain amyloid ...
Shin SC, Robinson-Papp J.
europepmc +8 more sources
Amyloid Proteins and Peripheral Neuropathy [PDF]
Cells, 2020 Painful peripheral neuropathy affects millions of people worldwide. Peripheral neuropathy develops in patients with various diseases, including rare familial or acquired amyloid polyneuropathies, as well as some common diseases, including type 2 diabetes
Mohammed M. H. Albariqi +3 more
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40 years of CEPARM: transforming amyloidosis related to transthyretin from neglect to recognition [PDF]
Arquivos de Neuro-PsiquiatriaVariant transthyretin amyloidosis with polyneuropathy (ATTRv-PN) and cardiomyopathy (ATTRv-CM), formerly known as familial amyloidotic polyneuropathy (FAP), is a severe, progressive disorder caused by mutations in the transthyretin (TTR) gene ...
Marcia Waddington Cruz +1 more
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Diagnostic pathway for cardiac amyloidosis from the healthcare professional’s perspective: results from the French DIAM-ATTR survey [PDF]
Annals of MedicineBackground Diagnosis of cardiac amyloidosis (CA) is complex and implicates several medical specialists. CA is usually suspected based on symptoms (‘red flags’) and non-invasive imagery.
Silvia Oghina +18 more
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Amyloidosis of the Femoral Neck: An Unusual Cause of Pathologic Fracture
Arthroplasty Today, 2022 The deposition of amyloid within human tissue can be detrimental to the proper functioning of multiple organ systems. While the infiltration of the amyloid protein within the musculoskeletal soft tissues can lead to compressive neuropathies, tendon ...
Christopher A. Worgul, MD +1 more
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Frontiers in Neurology, 2022 IntroductionHereditary transthyretin amyloidosis (hATTR) can cause multisystem organ disorders including polyneuropathy and cardiomyopathy. Amongst the many known pathologic mutations of the transthyretin (TTR) gene, the Val122Ile (V122I) mutation can be
Jeffrey Z. Shije +3 more
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Arquivos de Neuro-Psiquiatria, 2021 Background: Hereditary transthyretin-mediated (hATTR) amyloidosis with polyneuropathy is a rare, inherited, multisystem, and often fatal disease caused by a variant in transthyretin (TTR) gene.
Vanessa Cristina Cunha Sequeira +6 more
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Patterns of myelinated nerve fibers loss in transthyretin amyloid polyneuropathy and mimics
Annals of Clinical and Translational Neurology, 2022 Objective The present study was intended to analyze the characteristics of myelinated nerve fibers density (MFD) of transthyretin amyloid polyneuropathy (ATTR‐PN) and other similar neuropathies. Methods A total of 41 patients with ATTR‐PN, 58 patients of
Kang Du +11 more
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Frontiers in Human Neuroscience, 2022 Type 2 diabetes mellitus (T2DM) is associated with cognitive impairment in many domains. There are several pieces of evidence that changes in neuronal neuropathies and metabolism have been observed in T2DM.
Hao Lei +8 more
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Axoval neuropathy as initial manifestation of primary amyloidosis: report of a case submitted to bone marrow transplantation [PDF]
Arquivos de Neuro-Psiquiatria, 2004 Amyloidosis is a syndrome characterized by deposition of a highly insoluble protein material in the extracellular space that may affect several organs. It may be generalized and idiopathic (primary amyloidosis).
Orlando G. Povoas Barsottini +6 more
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