Results 111 to 120 of about 82,488 (290)
Gold Nanoparticles Guided by Self‐Assembling Peptides: From Sequence to Superstructure
ChemBioChem, EarlyView.Self‐assembling peptides act as versatile templates for gold nanoparticle (AuNP) synthesis. Their organization into discrete nanostructures or hydrogels enables control over AuNP morphology and assembly, offering new opportunities for functional nanomaterials.
Simone Adorinni, Silvia Marchesan
wiley +1 more source
Chemically Synthesized LRAD3‐D1 Interacts with N‐Terminal Domain of SARS‐CoV‐2 Spike Protein
ChemBioChem, EarlyView.Chemical synthesis, calcium‐templated in‐vitro folding and competitive ELISA assay reveal that only domain 1 of the LRAD3 ectodomain interacts with the severe acute respiratory syndrome‐related corona virus 2 (SARS‐CoV‐2) spike NTD, while domains 2 and 3 do not, providing valuable insight into ACE2‐independent viral entry pathways that may contribute ...
Mrinmoy Jana +5 more
wiley +1 more source
Amyloid‐Related Imaging Abnormality (ARIA) Beyond the APOE‐ε4 Allele
Chronic Diseases and Translational Medicine, EarlyView.Mechanism of action of monoclonal antibodies targeting Aβ in the treatment of AD. (A) Targets of various mAbs. (B) Mechanism of monoclonal antibody‐mediated clearance of Aβ. mAbs facilitate the clearance of Aβ by enhancing microglial‐mediated phagocytosis through the upregulation of TREM2 expression.
Valentinus Besin +5 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.Evidence is presented that prebiotically accessible mellitic (benzenehexacarboxylic) acid (MAc) is forming liquid droplets with short poly‐L‐lysine. The capacity of MAc to induce liquid‐liquid phase separation with short oligocations, along with abiotic synthesis routes, makes MAc a viable candidate for an ingredient of early prebiotic membraneless ...
Robert Dec +4 more
wiley +1 more source
Chinese Journal of Traumatology, 2012 【Abstract】Traumatic brain injury (TBI) is the lead-ing cause of mortality and disability among young indi-viduals in our society, and globally the incidence of TBI is rising sharply. Mounting evidence has indicated that apolipoprotein E (apoE: protein;
ZHOU Shuai, SUN Xiao-chuan
doaj
ChemPlusChem, EarlyView.The interaction between iron‐heme and amyloid‐β (Aβ) peptides can be strongly influenced by the cellular compartment. The presence of sodium dodecyl sulfate as a lipid‐mimicking system shows a protective role of the membrane by hindering both the formation of the heme–Aβ complex and the peroxidase‐like activity, reducing the accessibility of the lipid ...
Chiara Bacchella +5 more
wiley +1 more source
Potential Role of Protease Nexin‐2/Amyloid β‐Protein Precursor as a Cerebral Anticoagulanta [PDF]
, 1992 William E. Van Nostrand +2 more
openalex +1 more source
Redefining the Skin Barrier: A Microbiome‐Integrated Multilayered Defense Model
Barrier Immunity, EarlyView.ABSTRACT The skin constitutes a dynamic interface orchestrating a sophisticated multilayered defense system comprising physical, chemical, immune, and microbial barriers. This review synthesizes current understanding of the structural and functional integration of these barriers, emphasizing their synergistic interactions in maintaining cutaneous ...
Jingjing Xia +4 more
wiley +1 more source
Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues
ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang +7 more
wiley +1 more source