Results 191 to 200 of about 343,599 (390)

Racemic N1-Norphenserine and Its Enantiomers: Unpredicted Inhibition of Human Acetyl- and Butyrylcholinesterase and β-Amyloid Precursor Protein in vitro

open access: diamond, 2003
Nigel H. Greig   +7 more
openalex   +1 more source

Noninvasive imaging of amyloid‐beta and tau in rodent and nonhuman primate models

open access: yesVIEW, EarlyView.
Imaging of amyloid‐beta plaque and tau accumulation in rodent and nonhuman primate model of Alzheimer's disease. Created in BioRender. Ni R. 2026. https://BioRender.com/a97h5ec Abstract Neurodegenerative diseases are characterized by the aberrant accumulation of protein aggregates.
Ruiqing Ni, Axel Rominger
wiley   +1 more source

Uncoupled Packaging of Amyloid Precursor Protein and Presenilin 1 into Coat Protein Complex II Vesicles [PDF]

open access: hybrid, 2004
Jin Oh Kim   +4 more
openalex   +1 more source

Genetic Pigmentary Disorders: From Molecular Mechanisms to Clinical Manifestations

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Genetic pigmentary disorders represent a diverse group of genetic conditions characterized by alterations in melanin production and transport and melanocyte development, resulting from single‐gene pathological variants. These disorders encompass both hypopigmentary and hyperpigmentary phenotypes, affecting not only skin pigmentation but also ...
Ken Okamura, Tamio Suzuki
wiley   +1 more source

Amyloid precursor proteins protect neurons of transgenic mice against acute and chronic excitotoxic injuries in vivo

open access: hybrid, 1997
Eliezer Masliah   +7 more
openalex   +1 more source

Sialylation patterns in cerebral amyloid angiopathy

open access: yesBrain Pathology, EarlyView.
This study is the first to localize and evaluate sialylation modifications in the context of Alzheimer's Disease and Cerebral Amyloid Angiopathy, revealing a unique disease‐specific increase in intravascular sialylation. Abstract Glycosylation is the most common form of post‐translational modification in the brain and becomes significantly altered in ...
Caitlyn Fastenau   +8 more
wiley   +1 more source

14‐3‐3σ up‐regulation in the temporal cortex associates with tau pathology and reactive astroglia in Lewy body disorders

open access: yesBrain Pathology, EarlyView.
14‐3‐3 protein homeostasis is disrupted in Lewy body pathology, showing a diminution of six isotypes and overexpression of stratifin. The latter was associated with stratifin colocalization with tau pathology and reactive astrocytes. Platelets, as a peripheral biomarker source, mirrored inversely cortical 14‐3‐3 gene expression patterns in dementia ...
Laura Marsal‐García   +13 more
wiley   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

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