Mechanistic crosstalk between microglia and astrocytes in major depressive disorder. Abstract Major depressive disorder (MDD) is a complex psychiatric condition increasingly linked to chronic neuroinflammation, particularly in the context of aging, stress, and systemic comorbidities.
Gaurav Singhal+2 more
wiley +1 more source
Effect of berberine on cognitive function and β-amyloid precursor protein in Alzheimer's disease models: a systematic review and meta-analysis. [PDF]
Liu JY, Dai Y, He YX, Lin L.
europepmc +1 more source
Intracellular Aβ1-42 Aggregates Stimulate the Accumulation of Stable, Insoluble Amyloidogenic Fragments of the Amyloid Precursor Protein in Transfected Cells [PDF]
Austin J. Yang+3 more
openalex +1 more source
Tau protein aggregation and fibrillation have been examined in relationship to three metal ions in this study. The research was conducted to see the effects of Zn2+, Cu2+ and Fe3+ ions at different concentrations on tau′s conformation, cytotoxicity in SH‐SY5Y cells, and free thiol levels.
Mahzad Irandoust+6 more
wiley +1 more source
Amyloid precursor protein as a fibrosis marker in infants with biliary atresia. [PDF]
Kamp JC+13 more
europepmc +1 more source
Amyloid Protein Precursor Stimulates Excitatory Amino Acid Transport [PDF]
Eliezer Masliah+7 more
openalex +1 more source
Phytochemical Nanoparticles for the Treatment of Neurological Disorders
ABSTRACT Neurological disorders impose a significant burden on the healthcare systems. The latest published data by WHO indicated that stroke was the second leading cause of death globally in 2020, with Alzheimer's disease (AD) and other dementias in the seventh position.
Touraj Ehtezazi, Satyajit D. Sarker
wiley +1 more source
Amyloid precursor protein and presenilin-1 knock-in immunodeficient mice exhibit intraneuronal Aβ pathology, microgliosis, and extensive neuronal loss. [PDF]
Yeapuri P+13 more
europepmc +1 more source
Stimulation of amyloid precursor protein synthesis by adrenergic receptors coupled to cAMP formation [PDF]
Robert K. K. Lee+2 more
openalex +1 more source