Results 291 to 300 of about 343,599 (390)

Brain derived neurotrophic factor and secreted amyloid precursor protein-α response to moderate and high intensity exercise. [PDF]

Physiol Rep
Spencer FSE, Elsworthy RJ, Breen L, Bishop JRB, Lucas SJE, Aldred S.   +5 more
europepmc   +1 more source

Nutritional and Health Potential of Edible Seeds: Micronutrient Bioavailability and Mechanistic Insights

Food Science &Nutrition, Volume 14, Issue 2, February 2026.
Their bioactive constituents act through antioxidant, anti‐inflammatory, and metabolic‐regulating mechanisms, validating their classification as functional foods. Evidence from clinical and biochemical studies largely supports these benefits, although some claims stem from preliminary or in vitro findings.
Nighat Raza, Alina Sadaf, Reeha Mushtaq, Mirza Abid Mehmood, Luqman Amrao, Fakhar Islam, Muhammad Afzaal, Mohd Asif Shah   +7 more
wiley   +1 more source

Minocycline Treatment Improves Memory and Reduces Anxiety by Lowering Levels of Brain Amyloid Precursor Protein and Indoleamine 2,3-Dioxygenase in a Rat Model of Streptozotocin-Induced Alzheimer's Disease. [PDF]

Int J Mol Sci
Świątek G, Nowakowska-Gołacka J, Słomińska-Wojewódzka M, Glac W, Harackiewicz O, Kurowska-Rucińska E, Wrona D.   +6 more
europepmc   +1 more source

Neuro‐Immune Crosstalk: Molecular Mechanisms, Biological Functions, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
Neurons, immune cells, and other cellular components within the disease microenvironment (such as stromal cells and tumor cells) constitute a dynamically evolving ecosystem. Neurons directly modulate immune cell activity and inflammatory responses through the release of neurotransmitters (e.g., norepinephrine and CGRP), while also promoting tumor ...
Xin Guo, Hui Liu, Yu‐Jing Song, Jian‐Hua Wang, Danfeng Liu, Zhi‐Wei Zheng, Jia‐Jun Li, Boya Li, An Song, Wei He, Lei‐Lei Yang, Shuo Wang   +11 more
wiley   +1 more source

Amyloid precursor protein promotes MASH progression by upregulating death receptor 6-mediated hepatocyte apoptosis. [PDF]

J Biol Chem
Guo Y, Huang H, Yang L, Shen Q, Liu Z, Wang Q, Chen S, Pan J, Zhai H, Li Y, Xu L, Yu C, Xu C.   +12 more
europepmc   +1 more source

Fasting as Medicine: Mitochondrial and Endothelial Rejuvenation in Vascular Aging

Aging Cell, Volume 25, Issue 2, February 2026.
Aging impairs cerebrovascular health by driving mitochondrial dysfunction, oxidative stress, endothelial failure, and neurovascular uncoupling, leading to BBB breakdown and cognitive decline. In contrast, time‐restricted feeding/eating counteracts these mechanisms by restoring mitochondrial function, activating adaptive nutrient‐sensing pathways ...
Madison Milan, Eva Troyano‐Rodriguez, Jennifer Ihuoma, Sharon Negri, Rakesh Rudraboina, Aleksandra Kosmider, Shantipriya Awasthi, Priya Balasubramanian, Shannon Conley, Andriy Yabluchanskiy, Anna Csiszar, Zoltan Ungvari, Rafael de Cabo, Stefano Tarantini   +13 more
wiley   +1 more source

Amyloid precursor protein as a fibrosis marker in infants with biliary atresia. [PDF]

Pediatr Res
Kamp JC, Madadi-Sanjani O, Uecker M, Werlein C, Neubert L, Kübler JF, Obed M, Junge N, Welte T, Ruwisch J, Jonigk DD, Stolk J, Vieten G, Janciauskiene S.   +13 more
europepmc   +1 more source

NMNAT1 Activates Autophagy to Delay D‐Galactose‐Induced Aging in Cochlear Hair Cells

Aging Cell, Volume 25, Issue 2, February 2026.
The study presents mechanistic insights into cochlear hair cells aging using cellular and explant models. The assessment into NMNAT1 regulated NAD+ metabolism, autophagy, and aging in ARHL. NMNAT1 overexpression restores autophagic activity and decelerates aging in cochlear hair cells.
Yongjie Wei, Wenqing Yang, Han Wu, Mengdie Kong, Dachuan Fan, Yuhua Zhang, Nan Cheng, Jiawei Du, Lingna Guo, Yuyang Li, Ye Zhang, Qian Dai, Wei Cao, Jianming Yang, Qiaojun Fang   +14 more
wiley   +1 more source

Correction: Ramadan, W.S.; Alkarim, S. Ellagic Acid Modulates the Amyloid Precursor Protein Gene via Superoxide Dismutase Regulation in the Entorhinal Cortex in an Experimental Alzheimer's Model. <i>Cells</i> 2021, <i>10</i>, 3511. [PDF]

Cells
Ramadan WS, Alkarim S.
europepmc   +1 more source