Results 141 to 150 of about 14,023 (271)

RETRACTED ARTICLE: Age-dependent Increase in Desmosterol Restores DRM Formation and Membrane-related Functions in Cholesterol-free DHCR24−/− Mice [PDF]

, 2018
Cholesterol is a prominent modulator of the integrity and functional activity of physiological membranes and the most abundant sterol in the mammalian brain. DHCR24-knock-out mice lack cholesterol and accumulate desmosterol with age.
Crameri, Arames, Heppner, Frank, Kalvodova, Lucie, Kuehnle, Katrin, Kulic, Luka, Ledesma, Maria, Lütjohann, Dieter, Mohajeri, M., Nitsch, Roger, Skaanes-Brunner, Fabienne, Smith, Alicia, Thelen, Karin   +11 more
core  

Equimolar Production of Amyloid β-Protein and Amyloid Precursor Protein Intracellular Domain from β-Carboxyl-terminal Fragment by γ-Secretase [PDF]

, 2006
Nobuto Kakuda, Satoru Funamoto, Sousuke Yagishita, Mako Takami, Satoko Osawa, Naoshi Dohmae, Yasuo Ihara   +6 more
openalex   +1 more source

Internalization of Exogenously Added Memapsin 2 (β-Secretase) Ectodomain by Cells Is Mediated by Amyloid Precursor Protein [PDF]

, 2004
Xiangping Huang, Wan‐Pin Chang, Gerald Koelsch, Robert T. Turner, Florea Lupu, Jordan Tang   +5 more
openalex   +1 more source

Thioredoxin-80 is a product of alpha-secretase cleavage that inhibits amyloid-beta aggregation and is decreased in Alzheimer's disease brain [PDF]

, 2012
Akterin, Susanne, Gil Bea, Francisco Javier, Gutiérrez Rodríguez, Ángel, Persson, Torbjörn   +3 more
core   +1 more source

Synaptic NMDA Receptor Activation Stimulates α-Secretase Amyloid Precursor Protein Processing and Inhibits Amyloid-β Production [PDF]

, 2009
Sarah E. Hoey, Robert J. Williams, Michael S. Perkinton   +2 more
openalex   +1 more source

CHIPstabilizes amyloid precursor protein via proteasomal degradation and p53‐mediated trans‐repression of β‐secretase [PDF]

, 2015
Amir Kumar Singh, Uttam Pati
openalex   +1 more source

Proteolysis at the secretase and amyloidogenic cleavage sites of theβ-amyloid precursor protein by acetylcholinesterase and butyrylcholinesterase using model peptide substrates

, 1993
Mark de Serres, Douglas B. Sherman, William G. Chestnut, B M Merrill, O. Humberto Viveros, Emanuel J. Diliberto   +5 more
openalex   +2 more sources

A Splice Variant of β-Secretase Deficient in the Amyloidogenic Processing of the Amyloid Precursor Protein

, 2001
Ursula Bodendorf, Frauke Fischer, Dale L. Bodian, Gerd Multhaup, Paolo Paganetti   +4 more
openalex   +1 more source

The trans-Golgi network is a major site for α-secretase processing of amyloid precursor protein in primary neurons [PDF]

, 2018
Jing Zhi Anson Tan, Paul A. Gleeson
openalex   +1 more source

P2‐461: Selective modulation of gamma‐secretase cleavage of the amyloid precursor family of proteins [PDF]

, 2008
Carlo Sala Frigerio, Thomas Kukar, Pamela Osenkowski, Paul C. Engel, Michael S. Wolfe, Todd E. Golde, Dominic M. Walsh   +6 more
openalex   +1 more source