Results 161 to 170 of about 125,062 (284)

Zolpidem restores sleep and decreases amyloid in a mouse model

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Deficits in non–rapid eye movement (NREM) sleep facilitate Alzheimer's disease (AD) progression. Enhancing gamma‐aminobutyric acid‐ergic (GABAergic) signaling can restore sleep. Unbiased computational analysis identified zolpidem as high‐affinity GABA receptor modulator facilitating chloride transport that could slow AD.
Lu Yu   +6 more
wiley   +1 more source

Larynx Amyloidosis [PDF]

open access: yesEar, Nose & Throat Journal, 2003
Lee M, Akst, Lester D, Thompson
openaire   +2 more sources

Tau PET overlap index correlation with neuropathological findings

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION The tau positron emission tomography (PET) overlap index (OI) has shown promise in maximizing signal‐to‐noise for longitudinal tau PET imaging, particularly for early tau pathology, but requires validation against neuropathology.
Seokbeen Lim   +27 more
wiley   +1 more source

Obstructive sleep apnea severity, Alzheimer's disease plasma markers, and CSF brain amyloidosis and tau pathology

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION We examined obstructive sleep apnea (OSA) severity's association with Alzheimer's disease (AD) plasma biomarkers, independent or synergistic with cerebrospinal fluid (CSF) amyloid, and as a proof of concept, whether plasma amyloid beta (Aβ)42/Aβ40 with OSA severity improves detection of amyloidosis and tau pathology.
Omonigho Michael Bubu   +25 more
wiley   +1 more source

Genetic correlation analysis identifies TMEM106B, ACE, and ERC2 as genetic loci shared between Alzheimer's disease and primary psychiatric disorders

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Neuropsychiatric symptoms (NPSs) occur in up to 85% of Alzheimer's disease (AD) cases. Current treatments – repurposed from psychiatric disorders despite limited understanding of etiologic overlap – are often ineffective. METHODS To characterize the genetic overlap between AD and major psychiatric disorders and identify shared ...
Ajneesh Kumar   +14 more
wiley   +1 more source

Sex differences in neuromodulatory subcortical systems and their implications for Alzheimer's disease

open access: yesAlzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract Neuromodulatory subcortical systems (NSSs) are uniquely susceptible to dementia‐related pathology, leading to frequent molecular and behavioral impairments associated with altered function of these nuclei. Some of these systems display clear sex‐specific cytoarchitecture and signaling leading to distinct physiology and behavioral outputs in ...
Rosaria J. Rae   +53 more
wiley   +1 more source

Current Standards and Perspectives in Proteomics for Cardiac Amyloidosis. [PDF]

open access: yesAnal Chem
Greco F   +20 more
europepmc   +1 more source

A Case of Amyloid Light-Chain Amyloidosis Presenting as Colitis. [PDF]

open access: yesCureus
Prabakaran K   +7 more
europepmc   +1 more source

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