Results 171 to 180 of about 99,289 (260)

Hereditary Renal Amyloidosis Associated With a Novel Apolipoprotein A-II Variant

open access: yesKidney International Reports, 2017
Tatiana Prokaeva   +11 more
doaj   +1 more source

MCH‐Guard: Multimodal machine learning framework for risk stratification of cerebral microhemorrhage risk in the Alzheimer's Disease Neuroimaging Initiative

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Efficient cerebral microhemorrhage (MCH) monitoring is critical for anti‐amyloid therapy safety due to amyloid‐related imaging abnormalities with hemosiderin deposition (ARIA‐H) risk. We developed MCH‐Guard, a multimodal machine‐learning framework, to stratify MCH risk for Alzheimer's Disease Neuroimaging Initiaitive (ADNI ...
Alper Gel   +5 more
wiley   +1 more source

Baseline cerebrospinal fluid complement balance is associated with longitudinal memory decline in relation to plasma p‑tau181 levels in mild cognitive impairment

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION The role of complement in Alzheimer's disease (AD) remains unclear, particularly regarding tau pathology and memory decline. METHODS In 123 mild cognitive impairment (MCI) participants from Alzheimer's Disease Neuroimaging Initiative (ADNI), linear mixed‑effects models and Johnson–Neyman analysis examined associations of baseline ...
Zhinan Ye   +14 more
wiley   +1 more source

A National Survey of VA to Assess Availability of Care for Patients With Cardiac Amyloidosis. [PDF]

open access: yesJACC Adv
Yoo SGK   +8 more
europepmc   +1 more source

Synergistic association of insomnia and anxiety with cognitive impairment and dementia in older adults

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION We investigated the synergistic effects of comorbid insomnia and anxiety on cognitive impairment and dementia and explored the underlying plasma biomarker mechanisms. METHODS We included adults ≥ 60 years from the cross‐sectional cohort named The Shanghai Action to Prevent Dementia in the Elderly (SHAPE) and used data from the ...
Yan Chen   +12 more
wiley   +1 more source

TMEM59 regulates microglial Aβ phagocytosis in a TREM2‐dependent manner and acts as a potential therapeutic target for Aβ amyloidosis

open access: yesAlzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Microglia‐mediated clearance of amyloid beta (Aβ) is crucial for mitigating Alzheimer's disease (AD) progression, yet the molecular regulators of microglial phagocytosis remain incompletely understood. METHODS We assessed AD‐related phenotypes in 5xFAD mice with microglia‐specific deletion of transmembrane protein 59 (TMEM59 ...
Jian Meng   +13 more
wiley   +1 more source

Subtype specific artificial intelligence modelling of cardiac amyloidosis using echocardiography and electrocardiography. [PDF]

open access: yesEur Heart J Digit Health
James JK   +16 more
europepmc   +1 more source

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