Results 161 to 170 of about 71,732 (247)

Sudomotor dysfunction in people with type 1 diabetes with and without clinical peripheral neuropathy: A study from Pune, India

Journal of Diabetes Investigation, Volume 17, Issue 8, Page 1358-1366, August 2026.
ABSTRACT Background and Aims It is appreciated that current screening tools for diabetic peripheral neuropathy (DPN) often fail to detect early disease. Sudomotor (sweat gland) dysfunction, among the earliest manifestations of DPN, can be measured objectively by the SUDOSCAN® device. We compared SUDOSCAN® with conventional validated screening (Michigan
Rohan Shah, Rishikesh Behere, Aboli Bhalerao, Sanat Phatak, Alma Baptist, Chinmay S. Marathe, Chittaranjan S. Yajnik   +6 more
wiley   +1 more source

Primary Cutaneous Nodular Amyloidosis Presenting As Violaceous Patches on Bilateral Plantar Feet. [PDF]

Cureus
LaRow MA, Vance PK, Hohnadel M.
europepmc   +1 more source

Unravelling the Significance of Cystatin C and Bunina Bodies in Amyotrophic Lateral Sclerosis Pathogenesis

Neuropathology and Applied Neurobiology, Volume 52, Issue 4, August 2026.
ABSTRACT Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND), is a fatal neurodegenerative disease primarily affecting motor neurons. Two key protein inclusions found in lower motor neurons serve as neuropathological hallmarks of the disease in human tissue: the TDP43‐positive inclusion and the cystatin C‐positive Bunina body.
Sarah M. Granger, Rosemary A. Staniforth, Asbjorg Osk Snorradottir, Johnathan Cooper‐Knock, Kurt J. De Vos, J. Robin Highley   +5 more
wiley   +1 more source

Large Transthyretin Aggregates in Plasma of ATTR Amyloidosis Patients

JACC: Basic to Translational Science
Marianna Fontana, MD, PhD, Julian D. Gillmore, MD, PhD, Guglielmo Verona, PhD   +2 more
doaj   +1 more source

Prolonged Infections and Inflammatory Diseases in Common Variable Immune Deficiency as a Cause of AA Amyloidosis. [PDF]

J Clin Med
Reznik EV, Iarovoi MD, Romanova TS, Latysheva EA, Latysheva TV, Nazarov NA, Buianova AA, Vasiliadis IA, Repinskaia ZA, Strutynsky VA, Golukhov GN.   +10 more
europepmc   +1 more source

Biomolecular mechanisms of cardiac amyloidosis and its cardiovascular pathological basis. [PDF]

Front Immunol
Zhang L, Jiao Y, Guo J.
europepmc   +1 more source

Evaluation of serum neurofilament light chain, GFAP, and peripherin as biomarkers in hereditary transthyretin amyloidosis. [PDF]

Sci Rep
Anan I, Johannson G, Pilebro B, Wixner J, Heldestad V, Arvidsson S, Olsson M.   +6 more
europepmc   +1 more source

ULK4 and CDKN2A polymorphisms influence the risk of developing monoclonal gammopathy of undetermined significance

International Journal of Cancer, Volume 159, Issue 2, Page 410-422, 15 July 2026.
What's new? Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor to multiple myeloma, sharing substantial genetic features with overt malignancy. Given evidence implicating autophagy in myeloma risk, this study examined whether genetic variations in autophagy‐related genes influence MGUS susceptibility.
José Manuel Sánchez‐Maldonado, Angelica Macauda, Antonio José Cabrera‐Serrano, Hauke Thomsen, Murat Güler, Rob Ter Horst, Bethany van Guelpen, Pavel Vodicka, Stefano Landi, Subhayan Chattopadhyay, Pelin Ünal, Lucía Ruiz‐Durán, Delphine Casabonne, Hartmut Goldschmidt, Istemi Serin, María Carretero‐Fernández, Elena Cabezudo, Fernando Reyes‐Zurita, Aaron D. Norman, Ramón García‐Sanz, Gabriele Capurso, Per Hoffmann, Ulrika Pettersson‐Kymmer, Francisco Jiménez‐Romera, S. Vincent Rajkumar, Niels Weinhold, Ludmila Vodickova, Christian Langer, Angelika Stein, Abdulkadir Karismaz, Victor Moreno, Markus M. Nöthen, Karl‐Heinz Jöckel, Francesca Tavano, Joaquín Martínez‐López, Shaji K. Kumar, Juan Francisco Gutiérrez‐Bautista, Daniela Basso, Florentin Späth, Yolanda Benavente, Michelle A. T. Hildebrandt, Börge Schmidt, Tereza Sevcikova, Rui Manuel Vieira Reis, Yang Li, Miguel Ángel López‐Nevot, Mihai G. Netea, Daniele Campa, Alyssa Clay‐Gilmour, Susan L Slager, Kari Hemminki, Celine M Vachon, Asta Försti, Federico Canzian, Juan Sainz   +54 more
wiley   +1 more source

Management of relapsed/refractory AL amyloidosis. [PDF]

Blood Adv
Ling J, Sidiqi MH, Gertz M.
europepmc   +1 more source

Mechanistic Insights Into Metal Binding in the Aggregation Pathway of an Immunoglobulin Light Chain Protein

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Cardiac antibody light chain (AL) amyloidosis is characterized by the deposition of light chain (LC) variable domain (VL) protein in the heart. Transition metals such as copper and zinc have been suggested to enhance the toxicity of circulating soluble LCs. We show here how divalent metal ions influence the aggregation behavior of the patient‐derived λ‐
Tejaswini Pradhan, Riddhiman Sarkar, Joshua Leonhard‐Preu, Adrian F. Schnell, Nadine Schwierz, Bernd Reif   +5 more
wiley   +1 more source