Results 231 to 240 of about 98,806 (295)

Living with Transthyretin amyloid cardiomyopathy from a patient perspective. [PDF]

BMC Cardiovasc Disord
Bui QM, McCain J, Allen LA, Adler ED, Anderson C, Bloss C, Rabin BA, Urey MA.   +7 more
europepmc   +1 more source

POTASSIUM PERMANGANATE REACTION IN AMYLOIDOSIS

, 1982
Motohisa Nagamine, Satoru Tawara, Shukuro Araki   +2 more
openalex   +2 more sources

Cholesterol in mRNA‐Lipid Nanoparticles can be Replaced with the Synthetic Mycobacterial Monomycoloyl Glycerol Analogue MMG‐1

Advanced Functional Materials, Volume 35, Issue 51, December 16, 2025.
This study demonstrates that cholesterol in messenger RNA‐lipid nanoparticles (mRNA‐LNPs) can be completely replaced with an immunopotentiating lipid, i.e., a synthetic analogue of the C‐type lectin receptor agonist monomycoloyl glycerol (MMG‐1), without compromising physicochemical properties, in vivo transfection efficiency, and immunogenicity of the
Abhijeet G. Lokras, Saahil S. Baghel, Rune F. Jensen, Aneesh Thakur, Henrik Franzyk, Oskar Thofte, Marco Herrera‐Barrera, Madeleine Landry, Melike Ongun, Ahmad Tami, Marlene P. Thanthrige, Eva Callens, Corinne Beinat, Thomas Rades, Søren R. Paludan, Kristian Riesbeck, Ida Rosenkrands, Dennis Christensen, Gabriel K. Pedersen, Camilla Foged   +19 more
wiley   +1 more source

Transthyretin Amyloidosis-One of the Causes of Heart Failure in Patients with Severe Clinical Course of COVID-19. [PDF]

Int J Mol Sci
Gioeva Z, Mikhaleva L, Gutyrchik N, Shakhpazyan N, Pechnikova V, Midiber K, Kontorshchikov A, Zentsova E, Kakturskij L.   +8 more
europepmc   +1 more source

Therapeutic Antibodies for Mosquito‐Borne Orthoflavivirus Infections: Discovery, Engineering Approaches, and Advances in mRNA‐Based Delivery Systems

Advanced Therapeutics, Volume 8, Issue 12, December 2025.
This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli, Lucas Silva Rodrigues, Maria Clara Moura Pinheiro, Sylvia Barbosa Pinhate, Marcelo de Macedo Brígido, Andréa Queiroz Maranhão   +5 more
wiley   +1 more source

Polyneuropathy in hereditary and wildtype transthyretin amyloidosis, comparison of key clinical features and red flags. [PDF]

Sci Rep
Siemer JM, Grote-Levi L, Hänselmann A, Sassmann ML, Nay S, Ratuszny D, Körner S, Seeliger T, Hümmert MW, Dohrn MF, Huss A, Tumani H, Gödecke V, Heuser M, Bauersachs J, Bavendiek U, Skripuletz T, Gingele S.   +17 more
europepmc   +1 more source

The Immune Microenvironment in Liver Cancer: From Analysis to Targeting

Advanced Science, Volume 12, Issue 47, December 18, 2025.
This review explores how smart nanomedicines overcome the immunosuppressive tumor microenvironment in liver cancer. It details targeted delivery strategies and immune reprogramming mechanisms, including remodeling abnormal physiology, modulating metabolism, and inducing immunogenic cell death. The article highlights the paradigm shift toward multimodal
Jiaming Lan, Hao Li, Jian Xue, Yourong Duan, Jin Sun, Meng Niu   +5 more
wiley   +1 more source

Assessing the consistency of mass spectrometry, a clinical-laboratory model, and immunohistochemistry in amyloid subtyping: a Brazilian experience. [PDF]

Clin Proteomics
Szor RS, Castelli JB, Schuch RA, Carvalho VM, Rocha V.   +4 more
europepmc   +1 more source

Deletion of neuronal Idol ameliorates Alzheimer's disease–related pathologies via APOE receptors

Alzheimer's &Dementia, Volume 21, Issue 12, December 2025.
Abstract INTRODUCTION Overexpression of the low‐density lipoprotein receptor (LDLR) is known to decrease apolipoprotein E (APOE) levels and alleviate amyloid beta (Aβ) pathology. We hypothesized that inhibiting the Inducible Degrader of LDLR (IDOL), an enzyme that ubiquitinates LDLR for degradation, would increase endogenous LDLR levels and attenuate ...
Hande Karahan, Kelly Hartigan, Md Mamun Al‐Amin, Sutha K. John, Brianne McCord, H. R. Sagara Wijeratne, Dominic J. Acri, Daniel C. Smith, Luke C. Dabin, Hannah M. Rondon Cordero, Byungwook Kim, Do‐Hun Lee, Jungsu Kim   +12 more
wiley   +1 more source

Recurrent Pleural Effusions in an Elderly Female Patient With Renal Amyloidosis. [PDF]

Cureus
Bharadwaj AS, Munson K, Mustafa M, Poloju P.   +3 more
europepmc   +1 more source