Results 31 to 40 of about 90,332 (308)

Mechanisms underlying the initiation of cerebral betaamyloidosis and neurofibrillary tau pathology : new insights form transgenic mice [PDF]

, 2006
Numerous neurodegenerative disorders result from the aggregation of proteins that misfold and accumulate as fibrillar amyloid deposits in selectively vulnerable regions of the central nervous system.
Bolmont, Tristan
core   +1 more source

Expert recommendation from the Swiss Amyloidosis Network (SAN) for systemic AL-amyloidosis. [PDF]

, 2020
Systemic amyloidosis is a heterogeneous group of diseases associated with protein misfolding into insoluble beta-sheet rich structures that deposit extracellularly in different organs, eventually compromising their function.
Monney, P., Alessio Mylonas, Pazhenkottil, Aju P., Hübers, A., Gaspert, Ariana, Flammer, Andreas J., Kessler, C., Ulrike Bacher, Guido Stirnimann, Mihaylova, Violeta, Ariana Gaspert, Fehr, Thomas, Pazhenkottil, A., Adalgisa Condoluci, Gerull, S., Adrian Schmidt, Djerbi, N., Nadia Djerbi, Vetter, F., Kessler, Chiara, Laptseva, Natallia, Arosio, P., Laptseva, N., Bode, P., Mihaylova, V., Harald Seeger, Nkoulou, Ren, Thomas Suter, Alexandar Tzankov, Théaudin, M., Stefan Dirnhofer, Seeger, Harald, Chiara Kessler, Stämpfli, Simon F, Flammer, Andreas J., Axel Rüfer, Djerbi, Nadia, Dobner, Stephan W., Flammer, A.J., Flammer, Andreas J, Zweier, Markus, Meyer, Martin, Fehr, T., Concoluci, A., Heimgartner, Raphel, Dirnhofer, Stefan, Stampfli, Simon F., Peter Bode, Averaimo, Manuela, Hübers, Annemarie, Vetter, Friederike, Friederike Vetter, Schmidt, A., Andreas J. Flammer, Averaimo, M., Rüfer, A., Giorgio Treglia, Markus Zweier, Raphael Knöpfel, Nkoulou, René, Gerber, Bernhard, Thomas Fehr, Gerull, Sabine, Pazhenkottil, Aju, Manuela Averaimo, Bacher, V.U., Martin Meyer, Manka, Robert, Manka, R., Pierre Monney, Schwotzer, Rahel, Heimgartner, R., Mazzucchelli, Luca, Rüfer, Axel, Knöpfel, Raphael, Gerber, B., Monney, Pierre, Jung, Hans H., Suter, Thomas, Thomas Pabst, Simon F. Stämpfli, Théaudin, Marie, Suter, T., Treglia, Giorgio, Tzankov, A., Garofalo, M., Stirnimann, Guido, Sabine Gerull, Schmidt, Adrian, Pfister, Otmar, Pabst, Thomas, Stämpfli, S.F., Stirnimann, G., Bacher, Vera, Dirnhofer, S., Mylonas, A., Andrea Cavalli, Violeta Mihaylova, Bode, Peter, Arosio, Paolo, René Nkoulou, Condoluci, Adalgisa, Garofalo, Maura, Rahel Schwotzer, Zweier, M., Mazzucchelli, L., Bacher, Ulrike, Otmar Pfister, Jung, Hans H, Dobner, Stefan W., Schwotzer, R., Concoluci, Adalgisa, Annemarie Hübers, Meyer, M., Tzankov, Alexandar, Cavalli, Andrea, Robert Manka, Luca Mazzucchelli, Stephan W. Dobner, Mylonas, Alessio, Heimgartner, Raphael, Gaspert, A., Aju P. Pazhenkottil, Seeger, H., Hans H. Jung, Paolo Arosio, Pabst, T., Bacher, Vera Ulrike, Maura Garofalo, Natallia Laptseva, Bernhard Gerber, Pfister, O., Treglia, G., Dobner, S.W., Knöpfel, R., Raphael Heimgartner, Thaudin, Marie, Cavalli, A., Nkoulou, R., Jung, H.H., Marie Théaudin   +140 more
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Management of transthyretin amyloidosis. [PDF]

, 2021
Transthyretin amyloidosis (ATTR amyloidosis) is a disease caused by deposition of transthyretin fibrils in organs and tissues, which causes their dysfunction.
Monney, P., Alessio Mylonas, Hübers, A., Gaspert, Ariana, Kessler, C., Ulrike Bacher, Guido Stirnimann, Magini, G., Mihaylova, Violeta, Ariana Gaspert, Gerber, Bernhard; https://orcid.org/, Fehr, Thomas, Adalgisa Condoluci, Gerull, S., Adrian Schmidt, Djerbi, N., Nadia Djerbi, Vetter, F., Treglia, Giorgio; https://orcid.org/, Kessler, Chiara, Laptseva, Natallia, Arosio, P., Laptseva, N., Bode, P., Mihaylova, V., Giulia Magini, Harald Seeger, Bacher, U., Flammer, Andreas J; https://orcid.org/, Thomas Suter, Alexandar Tzankov, Théaudin, M., Stefan Dirnhofer, Seeger, Harald, Pazhenkottil, A.P., Chiara Kessler, Stämpfli, Simon F, Axel Rüfer, Djerbi, Nadia, Flammer, A.J., Flammer, Andreas J, Zweier, Markus, Meyer, Martin, Fehr, T., Dirnhofer, Stefan, Peter Bode, Averaimo, Manuela, Hübers, Annemarie, Vetter, Friederike, Friederike Vetter, Schmidt, A., Andreas J. Flammer, Averaimo, M., Rüfer, A., Giorgio Treglia, Markus Zweier, Raphael Knöpfel, Nkoulou, René, Gerber, Bernhard, Thomas Fehr, Gerull, Sabine, Manuela Averaimo, Martin Meyer, Manka, Robert, Manka, R., Pierre Monney, Schwotzer, Rahel, Heimgartner, R., Mazzucchelli, Luca, Rüfer, Axel, Knöpfel, Raphael, Gerber, B., Monney, Pierre, Suter, Thomas, Thomas Pabst, Simon F. Stämpfli, Théaudin, Marie, Suter, T., Treglia, Giorgio, Tzankov, A., Garofalo, M., Stirnimann, Guido, Sabine Gerull, Schmidt, Adrian, Pfister, Otmar, Pabst, Thomas, Stämpfli, S.F., Stirnimann, G., Dirnhofer, S., Mylonas, A., Andrea Cavalli, Violeta Mihaylova, Bode, Peter, Arosio, Paolo, Dobner, Stephan, René Nkoulou, Condoluci, Adalgisa, Garofalo, Maura, Rahel Schwotzer, Zweier, M., Mazzucchelli, L., Bacher, Ulrike, Otmar Pfister, Jung, Hans H, Schwotzer, R., Annemarie Hübers, Dobner, S., Meyer, M., Tzankov, Alexandar, Magini, Giulia, Cavalli, Andrea, Tzankov, Alexandar; https://orcid.org/, Robert Manka, Luca Mazzucchelli, Mylonas, Alessio, Heimgartner, Raphael, Gaspert, A., Aju P. Pazhenkottil, Seeger, H., Hans H. Jung, Paolo Arosio, Condoluci, A., Pabst, T., Maura Garofalo, Zweier, Markus; https://orcid.org/, Natallia Laptseva, Bernhard Gerber, Pfister, O., Treglia, G., Knöpfel, R., Raphael Heimgartner, Cavalli, A., Pazhenkottil, Aju P, Stephan Dobner, Nkoulou, R., Jung, H.H., Marie Théaudin   +136 more
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A retrospective study of isatuximab-pomalidomide-dexamethasone in relapsed/refractory systemic AL amyloidosis

Haematologica
Not available.
Sargam Rachit Vohra, Sriram Ravichandran, Darren Foard, Ana Martinez-Naharro, Lucia Venneri, Marianna Fontana, Carol J. Whelan, Philip N. Hawkins, Julian Gillmore, Helen J. Lachmann, Shameem Mahmood, Ashutosh D. Wechalekar   +11 more
doaj   +1 more source

Hereditary amyloidosis [PDF]

Arthritis & Rheumatism, 1970
AbstractA review of hereditary amyloidoses is provided by papers from a 1969 international symposium on primary amyloidosis. These discussions allow comparison of the amyloid neuropathy with onset in the lower extremities (Portuguese‐Japanese families), the neuropathy with onset in the upper extremities (Indiana‐Maryland families), the neuropathy and ...
C, Andrade, S, Araki, W D, Block, A S, Cohen, C E, Jackson, Y, Kuroiwa, J, Nissim, E, Sohar, V A, McKusick, M W, Van Allen   +9 more
openaire   +2 more sources

Senile Systemic Amyloidosis: Clinical Features at Presentation and Outcome

, 2013
Background Cardiac amyloidosis is a fatal disease whose prognosis and treatment rely on identification of the amyloid type. In our aging population transthyretin amyloidosis (ATTRwt) is common and must be differentiated from other amyloid types.
Banypersad, SM, Whelan, CJ, Lachmann, HJ, Gillmore, JD, Gibbs, SD, Hawkins, PN, McCarthy, CA, Sattianayagam, P, Rowczenio, D, Wechalekar, A, Venner, CP, Petrie, A, Dungu, J, Wassef, N, Pinney, JH, Gilbertson, JA   +15 more
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Role of cardiac MRI in the diagnosis of cardiac amyloidosis. Clinical cases

, 2021
Purpose. The aim of this work is to show the capabilities of late gadolinium enhancement cardiac magnetic resonance imaging (MRI) in the diagnosis of a rare disease such as cardiac amyloidosis. Materials and methods.
Olga V. Stukalova, Ekaterina A. Butorova
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Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

Misdiagnosis of hereditary amyloidosis as AL (Primary) amyloidosis [PDF]

, 2002
Background: Hereditary, autosomal dominant amyloidosis, caused by mutations in the genes encoding transthyretin, fibrinogen A -chain, lysozyme, or apolipoprotein A-I, is thought to be extremely rare and is not routinely included in the differential ...
Booth, D.R., Gilbertson, J.A., Hawkins, P.N., Booth, S.E., Lachmann, H.J., Gillmore, J.D., Bybee, A., Pepys, M.B.   +7 more
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Neurodegeneration and neurogenesis in mouse models of aging and Alzheimer's disease [PDF]

, 2003
As the proportion of senior citizens gradually increases, the behavioral changes that occur with normal aging and as a consequence of Alzheimer’s disease (AD) will afflict many of us in the future.
Bondolfi, Luca E.
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