Results 41 to 50 of about 148,376 (307)
Renal Amyloidosis Associated With 5 Novel Variants in the Fibrinogen A Alpha Chain Protein
Kidney International Reports, 2017 Fibrinogen A alpha chain amyloidosis is an autosomal dominant disease associated with mutations in the fibrinogen A alpha chain (FGA) gene, and it is the most common cause of hereditary renal amyloidosis in the UK.
Dorota Rowczenio +18 more
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Scandinavian Journal of Rheumatology, 1988 Recent studies have provided new insight into the pathogenesis of amyloidosis and have broadened our knowledge of the mechanisms of deposition and resolution of amyloid. In particular, the structure, synthesis and plasma clearance of the inflammation-associated amyloid precursor, SAA, have been extensively studied and the precursor-product relationship
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Avian Pathology, 1998 Although amyloid deposits have been described for more than a century and a half, its proteinaceous and fibrillar nature was not revealed until after 1950. Biochemical characterization of amyloids has brought to light that several non-related proteins can re-organize into amyloid fibrils. In some domestic and caged wild birds, and especially waterfowl,
Landman, W.J.M. +2 more
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Expert consensus recommendations to improve diagnosis of ATTR amyloidosis with polyneuropathy
Journal of Neurology, 2020 Amyloid transthyretin (ATTR) amyloidosis with polyneuropathy (PN) is a progressive, debilitating, systemic disease wherein transthyretin protein misfolds to form amyloid, which is deposited in the endoneurium. ATTR amyloidosis with PN is the most serious
D. Adams +9 more
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Amyloid: Journal of Protein Folding Disorders, 2022 Background This guideline has been developed jointly by the European Society of Haematology and International Society of Amyloidosis recommending non-transplant chemotherapy treatment for patients with AL amyloidosis.
A. Wechalekar +11 more
semanticscholar +1 more source
Systemic amyloidosis from A (AA) to T (ATTR): a review
Journal of Internal Medicine, 2020 Systemic amyloidosis is a rare protein misfolding and deposition disorder leading to progressive organ failure. There are over 15 types of systemic amyloidosis, each caused by a different precursor protein which promotes amyloid formation and tissue ...
Eli Muchtar +11 more
semanticscholar +1 more source
Pathophysiology and Therapeutic Approaches to Cardiac Amyloidosis.
Circulation Research, 2021 Often considered a rare disease, cardiac amyloidosis is increasingly recognized by practicing clinicians. The increased rate of diagnosis is in part due the aging of the population and increasing incidence and prevalence of cardiac amyloidosis with ...
J. Griffin, H. Rosenblum, M. Maurer
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The Laryngoscope, 1985 AbstractLocalized laryngeal amyloidosis is a benign, rare tumor of the larynx. Six cases of laryngeal amyloidosis were evaluated and treated from 1967 through 1984. One case is that of an 8‐year‐old female: the youngest reported case. Therapy is directed towards surgical resection.
M, Mitrani, H F, Biller
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Medicina, 2021 Amyloidoses are characterized by aggregation of proteins into highly ordered amyloid fibrils, which deposit in the extracellular space of tissues, leading to organ dysfunction.
Paola Rognoni +4 more
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