Results 81 to 90 of about 99,289 (260)

Exercise limitations in amyloid cardiomyopathy assessed by cardiopulmonary exercise testing—A multicentre study

ESC Heart Failure, Volume 12, Issue 2, Page 1326-1335, April 2025.
Abstract Aims Amyloid cardiomyopathy is caused by the deposition of light chain (AL) or transthyretin amyloid (ATTR) fibrils, that leads to a restrictive cardiomyopathy, often resulting in heart failure (HF) with preserved or reduced ejection fraction.
Robin Willixhofer, Mauro Contini, Michele Emdin, Damiano Magrì, Alice Bonomi, Elisabetta Salvioni, Fabrizio Celeste, Alberico Del Torto, Claudio Passino, Christophe D.J. Capelle, Chiara Arzilli, Emiliano Fiori, Nicolò Capra, Christina Kronberger, Nikita Ermolaev, Andreas Kammerlander, Beatrice Musumeci, Giuseppe Vergaro, Vincenzo Castiglione, René Rettl, Giacomo Tini, Andrea Baggiano, Iacopo Fabiani, Susanna Sciomer, Roza Badr Eslam, Piergiuseppe Agostoni   +25 more
wiley   +1 more source

Primary bladder amyloidosis as a cause of haematuria

, 2018
We report the case of a 46-year-old man who initially presented with macroscopic haematuria. Although initially concerning for a malignancy in the bladder, histology demonstrated a primary bladder amyloidosis that has remained stable for 6 years since ...
Nesbitt, AL, Khan, M, Lokan, J, Hoag, N
core   +1 more source

Pulmonary amyloidosis

, 2020
Amyloidosis is an orphan disease. Amyloidosis is uncommonly associated with respiratory disorders. The present article is a review of recently published data on pulmonary amyloidosis and a case report of alveolar and septal amyloid lung injury.
Zakharchenko S.P., Tret'yakov A.Yu., Tret'yakova V.A.   +2 more
core   +2 more sources

Engineering mRNA‐LNP Medicines for the Ageing Brain: Opportunities and Challenges for Neurodegenerative Diseases

Exploration, EarlyView.
This review highlights recent advances in engineering messenger RNA (mRNA)‐lipid nanoparticles (LNPs) to cross the ageing blood–brain barrier and target neurodegenerative diseases. It outlines design principles, delivery routes, and translational challenges, charting a roadmap towards clinical application of mRNA‐LNP therapeutics for neurodegenerative ...
Abdel Ali Belaidi, Denzil L. Furtado, Francesca Alves, Rebecca M. Nisbet, Scott Ayton, Ashley I. Bush   +5 more
wiley   +1 more source

Specific therapeutic options for transthyretin amyloidosis

The epidemiology of systemic amyloidosis has recently undergone a spectacular transformation. While light-chain amyloidosis remains a rare disease with a stable incidence, chronic inflammatory disease associated amyloidosis (AA) is diagnosed less ...
Zoltán Pozsonyi
core   +1 more source

Chemistry Underlying the Behavior of Food and Agricultural Components During Industrial Manufacturing Processes and Its Implications in Quality Assurance, Food Quality, and Food Safety Management: A Systematic Review

Food Safety and Health, EarlyView.
Industrial manufacturing processes have transformative effects on the components of food matrix. These transformations in food matrix and components have direct implications for quality assurance (QA), food quality (e.g., nutritional profile and texture), and food safety management (e.g., pathogen control and toxin mitigation). ABSTRACT This systematic
Chinaza Godswill Awuchi
wiley   +1 more source

Update on treatment of light chain amyloidosis

Haematologica, 2014
Light chain amyloidosis is the most common type of amyloidosis as a consequence of protein misfolding of aggregates composed of amyloid fibrils. The clinical features are dependent on the organs involved, typically cardiac, renal, hepatic, peripheral and
Shameem Mahmood, Giovanni Palladini, Vaishali Sanchorawala, Ashutosh Wechalekar   +3 more
doaj   +1 more source

Needs of amyloidosis patients and their care providers: design & first results of the  AMY-NEEDS research and care program

Orphanet Journal of Rare Diseases
Background Amyloidosis represents a rare yet heterogeneous multi-system disorder associated with a grave prognosis and an enormous psycho-emotional strain on patients, relatives, and caregivers.
Sandra Michaela Ihne-Schubert, Teresa Radovic, Saskia Fries, Stefan Frantz, Hermann Einsele, Stefan Störk, Silke Neuderth   +6 more
doaj   +1 more source

Dual-Energy SPECT and the Development of Peptide p5+14 for Imaging Amyloidosis

Molecular Imaging, 2017
Amyloidosis is associated with a number of rare diseases and is characterized by the deposition, in abdominothoracic organs and peripheral nerves, of extracellular protein fibrils, which leads to dysfunction and severe morbidity.
Jonathan S. Wall PhD, Stephen J. Kennel PhD, Emily B. Martin PhD   +2 more
doaj   +1 more source

Localized Secondary Amyloidosis of the Prostate

, 2014
Amyloidosis is an that is characterized the deposition of an abnormal proteinaceous material in extracellular tissue. Amyloidosis may be localized or systemic.
Nazım Emrah Koçer, Nebil Bal
core