Results 141 to 150 of about 242,580 (385)

Understanding Disease Heterogeneity and Patient Characteristics in Patients with Amyotrophic Lateral Sclerosis (ALS) [PDF]

, 2019
Background: Amytrophic lateral sclerosis (ALS) is a fatal neurologic disease that is projected to double in worldwide incidence in the next 20 years.
Mathew, Veena
core  

RPS3‐Enriched Extracellular Vesicles Mediate Liver‐Spinal Cord Inter‐Organ Communication

Advanced Science, EarlyView.
Spinal cord injury activates the liver to send extracellular vesicles loaded with RPS3 protein to the lesion site. These vesicles are taken up by neural stem cells and astrocytes, triggering NF‐κB signaling, impairing the regeneration of neurons and myelin, and promotes harmful inflammation, ultimately hindering recovery.
Peiwen Song, Zuomeng Wu, Yixiang Dong, Yunxiong Fang, Shiyu Bian, Daokuan Wang, Huang Fang, Yunlei Liu, Wang Ying, Jun Qian, Tianyu Han, Cailiang Shen   +11 more
wiley   +1 more source

Population-Based Surveillance of Amyotrophic Lateral Sclerosis in New Jersey, 2009-2011 [PDF]

, 2014
Heather Jordan, Jerald Fagliano, Lindsay Rechtman, Daniel Lefkowitz, Wendy Kaye   +4 more
openalex   +1 more source

Skin‐Conformal Myography for Real‐Time Hand Tracking Using a Laser‐Induced Graphene Strain Sensor Array

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
A skin‐conformal wearable device based on laser‐induced graphene is developed for continuous strain measurement across the circumference of the forearm for gesture recognition and hand‐tracking applications. Post material optimization, the strain sensor array is integrated with a wearable wireless readout circuit for real‐time control of a robotic arm,
Vinay Kammarchedu, Monther AlSiyabi, Aida Ebrahimi   +2 more
wiley   +1 more source

Robust Dysarthric Speech Recognition with GAN Enhancement and LLM Correction

Advanced Intelligent Systems, EarlyView.
This study tackles dysarthric speech recognition by combining generative adversarial network (GAN)‐generated synthetic data with large language model (LLM)‐based error correction. The approach integrates three key elements: an improved CycleGAN to generate synthetic dysarthric speech for data augmentation, a multimodal automatic speech recognition core
Yibo He, Kah Phooi Seng, Chee Shen Lim, Li Minn Ang   +3 more
wiley   +1 more source

Application of botulinum toxin to treat sialorrhea in amyotrophic lateral sclerosis patients: a literature review

Einstein (São Paulo)
Amyotrophic lateral sclerosis is a progressive and fatal neurodegenerative disease characterized by the degeneration of motor neurons, which are the central nervous system cells that control voluntary muscle movements.
Ademar Francisco de Oliveira Filho, Gêssyca Adryene de Menezes Silva, Débora Milenna Xavier Almeida   +2 more
doaj   +1 more source

Intraperitoneally administered IgG from patients with amyotrophic lateral sclerosis or from an immune-mediated goat model increase the levels of TNF-α, IL-6, and IL-10 in the spinal cord and serum of mice [PDF]

, 2016
Izabella Obál, Gergely Klausz, Yvette Mándi, Mária A. Deli, László Siklós, József I. Engelhardt   +5 more
openalex   +1 more source

Infantile‐Onset Ascending Hereditary Spastic Paraplegia due to a Homozygous ALS2 Exons 24–25 Deletion: Expanding the Genotypic Spectrum

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT We describe a novel homozygous intragenic deletion in the ALS2 gene in an 8‐year‐old boy with Infantile‐onset Ascending Hereditary Spastic Paraplegia (IAHSP) and oculomotor apraxia, thereby contributing to the expanding genetic landscape of ALS2‐related disorders.
Vito Luigi Colona, Maria Gnazzo, Silvia Genovese, Gessica Vasco, Lorena Travaglini, Maurizio Sabbadini, Marina Macchiaiolo, Francesco Nicita, Jacopo Sartorelli, Carmelo Piscopo, Enrico Castelli, Enrico Bertini, Andrea Bartuli, Antonio Novelli, Gessica Della Bella, Davide Vecchio   +15 more
wiley   +1 more source

“Patients with amyotrophic lateral sclerosis (ALS) are usually nice persons”—How physicians experienced in ALS see the personality characteristics of their patients [PDF]

, 2016
Theresa Mehl, Berit Jordan, Stephan Zierz   +2 more
openalex   +1 more source

Technology to support autonomy in patients with Amyotrophic Lateral Sclerosis

, 2022
Paola Masiello
openalex   +2 more sources