Results 221 to 230 of about 148,501 (250)

Amyotrophic lateral sclerosis

2015
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease of the motor system characterized by focal and then generalized weakness leading to paralysis and death from respiratory failure. Symptoms arise from the loss of corticospinal (upper), and brainstem and spinal (lower) motor neurons.
R.H. Brown, O.M. Peters
openaire   +2 more sources

Introducing Amyotrophic lateral sclerosis.

Archives italiennes de biologie, 2011
Introducing ALS at present times leads to re-define the concept of motor neuron selectivity which characterizes this disorder. In fact, multiple systems including skin, liver, and bone marrow are altered in ALS patients. The motor neuron is still the focus of the disorder and the extended pathology did not modify the concept of ALS as a devastating ...
Silani V, Meininger V, FORNAI, FRANCESCO
openaire   +5 more sources

Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis

Science, 2006
M. Neumann, Deepak M. Sampathu, L. Kwong, Adam C. Truax, Matthew C. Micsenyi, T. T. Chou, J. Bruce, T. Schuck, M. Grossman, C. Clark, L. McCluskey, B. Miller, E. Masliah, I. Mackenzie, H. Feldman, W. Feiden, H. Kretzschmar, J. Trojanowski, V. Lee   +18 more
semanticscholar   +1 more source

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

Nature, 1993
D. Rosen, T. Siddique, D. Patterson, D. Figlewicz, P. Sapp, A. Hentati, D. Donaldson, J. Goto, J. O'Regan, H. Deng, Z. Rahmani, A. Krizus, D. McKenna-Yasek, A. Cayabyab, Sandra M. Gaston, R. Berger, Rudolph E. Tanzi, John J. Halperin, B. Herzfeldt, Raymond Van den Bergh, W. Hung, T. Bird, G. Deng, Donald W. Mulder, C. Smyth, Nigel G. Laing, E. Soriano, M. Pericak-Vance, J. Haines, Guy A. Rouleau, James S. Gusella, H. Horvitz, Robert H. Brown   +32 more
semanticscholar   +1 more source

El Escorial revisited: Revised criteria for the diagnosis of amyotrophic lateral sclerosis

Amyotrophic Lateral Sclerosis and other Motor Neuron Disorders, 2000
B. Brooks, Robert G. Miller, M. Swash, T. Munsat   +3 more
semanticscholar   +1 more source

Amyotrophic Lateral Sclerosis

AJN, American Journal of Nursing, 1976
M A, Boyle, R L, Ciuca
openaire   +2 more sources

Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis

Science, 2009
T. Kwiatkowski, D. A. Bosco, A. L. Leclerc, E. Tamrazian, C. Vanderburg, C. Russ, A. Davis, J. Gilchrist, E. Kasarskis, T. Munsat, P. Valdmanis, G. Rouleau, B. Hosler, P. Cortelli, P. D. de Jong, Y. Yoshinaga, J. Haines, M. Pericak-Vance, J. Yan, N. Ticozzi, T. Siddique, D. McKenna-Yasek, P. Sapp, H. Horvitz, J. Landers, R. H. Brown   +25 more
semanticscholar   +1 more source

Amyotrophic lateral sclerosis: a neurodegenerative disorder poised for successful therapeutic translation

Nature Reviews Drug Discovery, 2023
H Joseph Reiser, Fiona H Marshall, Richard J Mead   +2 more
exaly  

The new (Version 9) American Joint Committee on Cancer tumor, node, metastasis staging for cervical cancer

Ca-A Cancer Journal for Clinicians, 2021
Alexander B Olawaiye, David G Mutch
exaly  

TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.

Biochemical and Biophysical Research Communications - BBRC, 2006
T. Arai, M. Hasegawa, H. Akiyama, K. Ikeda, T. Nonaka, H. Mori, D. Mann, K. Tsuchiya, Mari Yoshida, Y. Hashizume, Tatsuro Oda   +10 more
semanticscholar   +1 more source