Results 251 to 260 of about 235,642 (386)

Identification of Phosphorylation Sites in PHF-TAU from Patients with Guam Amyotrophic Lateral Sclerosis/Parkinsonism-dementia Complex [PDF]

, 1996
Madhumalti Mawal-Dewan, Luise M. Schmidt, Brian J. Balin, Daniel P. Perl, Virginia M.‐Y. Lee, John Q. Trojanowski   +5 more
openalex   +1 more source

Mapping protein–protein interactions by mass spectrometry

Mass Spectrometry Reviews, EarlyView.
Abstract Protein–protein interactions (PPIs) are essential for numerous biological activities, including signal transduction, transcription control, and metabolism. They play a pivotal role in the organization and function of the proteome, and their perturbation is associated with various diseases, such as cancer, neurodegeneration, and infectious ...
Xiaonan Liu, Lawrence Abad, Lopamudra Chatterjee, Ileana M. Cristea, Markku Varjosalo   +4 more
wiley   +1 more source

Muscle MRI quantifies disease progression in amyotrophic lateral sclerosis. [PDF]

J Neurol Neurosurg Psychiatry
Klickovic U, Zampedri L, Zafeiropoulos N, Ziff OJ, Sinclair CD, Wastling S, Dudziec M, Allen J, Trimmel K, Howard RS, Malaspina A, Sharma N, Sidle KC, Shah S, Nasel C, Yousry TA, Greensmith L, Morrow JM, Thornton JS, Fratta P.   +19 more
europepmc   +1 more source

Efficacy and Safety of IncobotulinumtoxinA for Treatment of Sialorrhea: A Multicenter, Phase 3 Study in Japan

Movement Disorders Clinical Practice, EarlyView.
This study demonstrated significant treatment efficacy and safety of incobotulinumtoxinA injection in Japanese patients with chronic sialorrhea caused by Parkinson's disease and other neurological conditions. Suppression of salivary secretion and improvement in drooling symptoms were also observed throughout 48 weeks.
Nobutaka Hattori, Yohei Mukai, Noriko Nishikawa, Kazuko Hasegawa, Masahiko Tomiyama, Yasuyoshi Kimura, Yoshio Tsuboi, Ryosuke Takahashi, Ryota Nakamura, Yuishin Izumi, Hirohisa Watanabe, Morinobu Seki, Kenji Sekiguchi, Shohei Tateishi, Yusaku Matsushita, Yusaku Nakamura   +15 more
wiley   +1 more source

Anti‐Neuroinflammatory and Anti‐Inflammatory Effects of the NLRP3 Inhibitor NT‐0796 in Subjects with Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Inhibition of Nod‐like receptor protein 3 (NLRP3) inflammasome within the central nervous system (CNS) is a promising therapeutic target for the treatment of Parkinson's disease (PD). Objectives This phase 1b open‐label study was conducted in elderly healthy volunteers (HV) and PD patients.
Nicholas Clarke, Peter Thornton, Valérie Reader, Nicola Lindsay, Zsofia Digby, Bianca Mullen, Michelle Gorman, Eric Jacobson, Grant Langdon, Hilary Johnstone, Alistair Wheeler, Alan P. Watt   +11 more
wiley   +1 more source

Mimickers of amyotrophic lateral sclerosis

Annals of Indian Academy of Neurology, 2019
Shubham Dubey, Ayush Dubey
openaire   +3 more sources

Amyotrophic Lateral Sclerosis Associated with Genetic Abnormalities in the Gene Encoding Cu/Zn Superoxide Dismutase: Molecular Pathology of Five New Cases, and Comparison with Previous Reports and 73 Sporadic Cases of ALS [PDF]

, 1998
Paul G. Ince, Janine Tomkins, Janet Y. Slade, Nicola Thatcher, Pamela J. Shaw   +4 more
openalex   +1 more source

The dynamic course of spontaneous muscular contractions assessed using multiple‐point acquisition in diffusion‐weighted stimulated echo imaging

Magnetic Resonance in Medicine, EarlyView.
Abstract Purpose The temporal course of spontaneous mechanical activities of musculature (SMAMs) is investigated using a novel multiple‐point diffusion‐weighted stimulated echo imaging sequence (MP‐DW‐STE) with adapted spatial and temporal resolution. For this purpose, different sequence settings and measurement parameters are applied. Methods A single‐
Martin Schwartz, Petros Martirosian, Victor Fritz, Günter Steidle, Bin Yang, Fritz Schick   +5 more
wiley   +1 more source

The emerging role of cellular senescence in amyotrophic lateral sclerosis. [PDF]

Front Neurosci
Tan X, Gao N.
europepmc   +1 more source

Extrapyramidal involvement in amyotrophic lateral sclerosis: backward falls and retropulsion

, 1999
Joy Desai, Michael Swash
openalex   +1 more source