Ecdysteroids: A novel class of anabolic agents? [PDF]
Biology of Sport, 2015 Increasing numbers of dietary supplements with ecdysteroids are marketed as “natural anabolic agents”. Results of recent studies suggested that their anabolic effect is mediated by estrogen receptor (ER) binding. Within this study the anabolic potency of
MK Parr +4 more
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Anabolic agents and bone quality. [PDF]
Clin Orthop Relat Res, 2011 The definition of bone quality is evolving particularly from the perspective of anabolic agents that can enhance not only bone mineral density but also bone microarchitecture, composition, morphology, amount of microdamage, and remodeling dynamics.This review summarizes the molecular pathways and physiologic effects of current and potential anabolic ...
Sibai T, Morgan EF, Einhorn TA.
europepmc +5 more sources
Role of anabolic agents in colorectal carcinogenesis: Myths and realities (Review). [PDF]
Oncol Rep, 2019 Colorectal cancer (CRC) is one of the four leading causes of cancer-related mortality worldwide. Even though over the past few decades the global scientific community has made tremendous efforts to understand this entity, many questions remain to be ...
Krasanakis T +8 more
europepmc +2 more sources
Combination therapy of anabolic agents and bisphosphonates on bone mineral density in patients with osteoporosis: a meta-analysis of randomised controlled trials. [PDF]
BMJ Open, 2018 Objective We aimed to determine whether the concomitant combination therapy of anabolic agents and bisphosphonates produces more effects on bone mineral density (BMD) than anabolic agents alone in patients with osteoporosis.
Lou S, Lv H, Li Z, Zhang L, Tang P.
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Comparison of the Clinical Efficacy of Anabolic Agents and Bisphosphonates in the Patients With Osteoporotic Vertebral Fracture: Systematic Review and Meta-analysis of Randomized Controlled Trials. [PDF]
NeurospineObjective We investigated the clinical efficacy of anabolic agents compared with bisphosphonates (BPs) for the incidence of new osteoporotic vertebral fracture (OVF) and fracture healing of OVF in the patients with OVF via meta-analyses of randomized ...
Jeon I +5 more
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Role of bone-anabolic agents in the treatment of breast cancer bone metastases. [PDF]
Breast Cancer Res, 2014 Skeletal metastases are an incurable complication afflicting the majority of patients who die from advanced breast cancer. They are most often osteolytic, characterized by net bone destruction and suppressed new bone formation. Life expectancy from first
Suvannasankha A, Chirgwin JM.
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Anabolic agents: recent strategies for their detection and protection from inadvertent doping. [PDF]
Br J Sports Med, 2014 According to the World Anti-Doping Agency (WADA) Prohibited List, anabolic agents consist of exogenous anabolic androgenic steroids (AAS), endogenous AAS and other anabolic agents such as clenbuterol and selective androgen receptor modulators (SARMs ...
Geyer H, Schänzer W, Thevis M.
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Reversal of the diabetic bone signature with anabolic therapies in mice
Bone Research, 2023 The mechanisms underlying the bone disease induced by diabetes are complex and not fully understood; and antiresorptive agents, the current standard of care, do not restore the weakened bone architecture.
Silvia Marino +11 more
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Anabolic agents: what is beyond osteoporosis? [PDF]
Osteoporos Int, 2018 Liu Y +6 more
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Anabolic and anticatabolic agents in critical care
Current Opinion in Critical Care, 2016 Purpose of review A complex network of hormones and other effectors characterize the hypermetabolic response in critical illness; these mediators work together to induce numerous pathophysiologic alterations. Increased incidence of infection, multiorgan failure, long-term debilitation, delays in rehabilitation, and death result
Mile, Stanojcic +2 more
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