Results 151 to 160 of about 3,324,374 (323)

Microgravity‐induced changes in skeletal muscle and possible countermeasures: What we can learn from bed rest and human space studies

Experimental Physiology, EarlyView.
Abstract Despite exercise countermeasures to sustain health and performance in spaceflight, complete maintenance of muscle mass and functions in microgravity is still not possible for most astronauts. The principal cause of the limited effectiveness of existing exercise countermeasures is the difficulty in achieving full loading forces in space.
Alessandra Bosutti, Bergita Ganse, Nicola A. Maffiuletti, Rob C. I. Wüst, Gustav J. Strijkers, Andy Sanderson, Hans Degens   +6 more
wiley   +1 more source

Theoretical-Experimental Analysis to Elucidate the Mechanism of Action of Novel Anabolic Agents. [PDF]

Molecules
Quiroga I, Cardenas-Garcia M, Hernández-Linares MG, Guerrero-Luna G, Flores-Manuel F.   +4 more
europepmc   +1 more source

Molecular pathophysiology of chronic kidney disease–mineral and bone disorder: Focus on the fibroblast growth factor 23–Klotho axis and bone turnover dynamics

Experimental Physiology, EarlyView.
Abstract Chronic kidney disease–mineral and bone disorder (CKD‐MBD) is a major complication of chronic kidney disease (CKD), characterized by disruptions in mineral metabolism, abnormal bone turnover and vascular calcification, which collectively increase the risk of fractures and cardiovascular disease.
Alief Waitupu, Laras Pratiwi, Henry Sutanto, Djoko Santoso, Decsa Medika Hertanto   +4 more
wiley   +1 more source

Prevention of bone dehiscence associated with orthodontic tooth movement by prophylactic injection of bone anabolic agents in mice. [PDF]

Sci Rep
Qi J, Matsumoto Y, Xie C, Rashed F, Ono T, Aoki K.   +5 more
europepmc   +1 more source

Redox‐regulated signalling of adaptations to contractile activity in skeletal muscle: Implications for age‐related muscle weakness

Experimental Physiology, EarlyView.
Abstract Skeletal muscle adaptation to contractile activity is modulated by redox signalling, primarily through reactive oxygen species (ROS) such as hydrogen peroxide (H2O2). Early research framed ROS as deleterious byproducts of exercise, but subsequent studies have established their roles as signalling molecules involved in mitochondrial biogenesis,
Malcolm J. Jackson
wiley   +1 more source

Nature-Mimicking 3-Aryl-2h-Chromene Derivatives as Potential Bone Anabolic Agents

Sonu Khanka, Kundan Singh Rawat, Priyanka Pandey, Shyamal Pal, Ravi P. Vats, Rajat Rathur, Kriti Sharma, Divya Dipali, Divya Singh, Atul Goel   +9 more
openalex   +1 more source

Dasatinib as a Bone-Modifying Agent: Anabolic and Anti-Resorptive Effects

, 2012
Antonio García-Gómez, Enrique M. Ocio, Edvan de Queiroz Crusoé, Carlos Santamaría, Pilar Hernández-Campo, Juan F. Blanco, Fermín Sánchez‐Guijo, Teresa Hernández‐Iglesias, Jesús G. Briñón, Rosa M. Fisac-Herrero, Francis Y. Lee, Atanasio Pandiella, Jesús F. San Miguel, Mercedes Garayoa   +13 more
openalex   +2 more sources

The effect of artificial gravity on the outcome of a two‐week resistance vibration exercise programme: BRAVE study

Experimental Physiology, EarlyView.
Abstract We evaluated the feasibility and efficacy of a 2‐week training programme comprising resistance vibration exercise (RVE) without and with artificial gravity (AG). Participants (n = 24) were divided into three groups: (i) URVE: upright loaded squat exercise; (ii) HRVE: horizontal loaded squat exercise; and (iii) AGRVE: loaded squat exercise ...
Igor B. Mekjavic, Riccardo G. Sorrentino, Jack Fortune, Jason T. Fisher, Lydia Tsoutsoubi, Leonidas G. Ioannou, Andrej Vovk, Matej Supej, Adam C. McDonnell, Urša Ciuha   +9 more
wiley   +1 more source

Endocrine and androgenic response to altitude training in professional cyclists

The Journal of Physiology, EarlyView.
Abstract figure legend Steroidal and endocrine variables are altered during altitude training. Abstract This study investigated endocrine and steroidal blood markers in 31 male elite cyclists monitored over 7 weeks, including a 3 week altitude training camp either at 2050 m (n = 19) or 3000 m (n = 12).
Raphael Faiss, Bastien Krumm, Claes Cubel, Magnus Bak Klaris, Lasse Vestli Baekken, Yvette Dehnes, Jenna Goodrum, Geoff Miller, James Spragg, Martin Faulhaber, Francesco Botrè, Carsten Lundby   +11 more
wiley   +1 more source

PTHrP(1–36) as a skeletal anabolic agent for the treatment of osteoporosis

, 1996
Andrew F. Stewart
openalex   +1 more source