Results 161 to 170 of about 3,709,556 (294)

Targetable Vulnerabilities in MYC‐Driven B Cell Lymphomas Resistant to BCR Extinction

Hematological Oncology, Volume 44, Issue 2, March 2026.
ABSTRACT Polatuzumab vedotin, an antibody‐drug conjugate (ADC) targeting the B cell receptor (BCR) signaling subunit CD79B, has recently entered frontline therapy for diffuse large B cell lymphoma (DLBCL) and high‐grade B cell lymphoma (HGBCL), achieving encouraging clinical results. However, MYC‐driven B cell lymphomas, particularly HGBCL with MYC and
Silvia Brambillasca, Nicara Chantal Parr, Adriana Palmeri, Adrian Andronache, Hiroshi Arima, Giovanni Faga’, Brian Leuzzi, Laura Perucho, Michela Robusto, Maurizio Pasi, Federica Mainoldi, Daniele Fancelli, Mario Varasi, Gabriele Varano, Ciro Mercurio, Stefano Casola   +15 more
wiley   +1 more source

Albiflorin Relieves Intervertebral Disc Degeneration Through Inhibiting Nucleus Pulposus Cell via the p38 MAPK/NF‐κB Pathway

Immunity, Inflammation and Disease, Volume 14, Issue 3, March 2026.
ABSTRACT Background As a chronic musculoskeletal disorder, intervertebral disc degeneration (IDD) is a leading cause of low back pain. Inflammatory response plays a key role in the IDD progression. Albiflorin (AF), a bioactive compound derived from Paeonia lactiflora, exhibits anti‐inflammatory effects in various diseases. However, the effects of AF on
Kai Yang, Yanping Cheng, Dan Yang
wiley   +1 more source

Post-COVID-19 subacute painless thyroiditis: a case report in an anabolic androgenic steroid user. [PDF]

BMC Infect Dis
Skrzypiec-Spring M, Kuliczkowska-Płaksej J, Szeląg A, Bolanowski M.   +3 more
europepmc   +1 more source

Effects of anabolic agents on protein breakdown in L6 myoblasts.

Biochemical Journal, 1983
F. Ballard, G. Francis
semanticscholar   +1 more source

Repeated (Weekly) Intra‐Articular Injections of Sulfated Galactans Attenuate Cartilage Degeneration in a Rat Model of Osteoarthritis

Journal of Orthopaedic Research, Volume 44, Issue 3, March 2026.
Knee osteoarthritis (OA) is characterized by progressive cartilage degeneration and remains a major cause of joint dysfunction with limited disease‐modifying therapies. This study evaluated the therapeutic potential of sulfated galactans (SG) extracted from Gracilaria fisheri in a rat OA model induced by anterior cruciate ligament transection and ...
Nirada Srianake, Amarin Thongsuk, Scarlett Desclaux, Thitiya Phuagpan, Jiraporn Sriwong, Alita Kongchanagul, Wanwisa Himakhun, Ruedee Hemstapat, Kanokpan Wongprasert   +8 more
wiley   +1 more source

Asian Federation of Osteoporosis Societies 2025 consensus on atypical femoral fractures in patients with osteoporosis. [PDF]

Osteoporos Sarcopenia
Valleenukul T, Songpatanasilp T, Jaisamrarn U, Anuraklekha S, Srinonprasert V, Chaiamnuay S, Unnanuntana A, Wattanachanya L, Nimitphong H, Kulachote N, Phruetthiphat OA, Jarayabhand R, Amphansap T, Vanitcharoenkul E, Chotiyarnwong P, Mori S, Kim KK, Yeap SS, Paramasivam SS, Gani L, Cheung CL, Li-Yu J, Sandoval MA, Chen CH, Charatcharoenwitthaya N.   +24 more
europepmc   +1 more source

Cancer Comorbidities: Clinical Impacts, Mechanistic Insights, and Management Strategies

MedComm – Oncology, Volume 5, Issue 1, March 2026.
This review focuses on cancer comorbidities, examining their clinical impacts and mechanistic insights. It further examines key management challenges, including evidence gaps, the lack of precise assessment tools, limited management frameworks, and underdeveloped multidisciplinary collaborations.
Taoxing Peng, Siyi Chen, Xin He, Yuxin Yang, Yuexiang Ren, Yuxuan Sun, Fuli Shi, Yangfeng Lv, Xiangqiong Wen, Yujian Wen, Peng Yu, Weizhu Liu, Qiongfeng Chen, Xianhe Yang, Shan Xu, Jianming Li   +15 more
wiley   +1 more source

Abaloparatide and paclitaxel combination therapy Improves bone volume and tumor burden in Bone-Metastatic breast cancer. [PDF]

J Bone Oncol
Miller JS, Kane JF, Ward PA, Shawkey M, Watkins A, Johnson RW, Rhoades JA.   +6 more
europepmc   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source

Bone Optimization for Perioperative Spine Patients: A Multidisciplinary Approach at a Single Academic Center. [PDF]

J Clin Med
Suarez-Nieto MV, Malacon K, Fox A, Lopez Isidro MC, Wadhwa H, Hu SS, Zygourakis CC.   +6 more
europepmc   +1 more source