Results 51 to 60 of about 3,709,556 (294)
Advanced Science, EarlyView.Researchers identified a pancreatic cancer subset with low global protein synthesis but heightened translation of stress‐response genes like ATF4, rendering cells resistant to chemotherapy and apoptosis. These tumors depend on serine and cysteine from surrounding cancer‐associated fibroblasts (CAFs), which shift to produce serine by curbing collagen ...
Sauyeun Shin +25 more
wiley +1 more source
Acute myocardial infarction in a young male wrestler: A case report
ARYA Atherosclerosis, 2015 BACKGROUND: Anabolic steroids have been widely used in recent years. It could adversely affect the cardiovascular system. Non-traditional risk factors for coronary heart diseases (CHDs) have raised great concern.
Hoorak Poorzand +3 more
doaj
Asia-Pacific consensus on long-term and sequential therapy for osteoporosis
Osteoporosis and SarcopeniaObjectives: This study aimed to present the Asia-Pacific consensus on long-term and sequential therapy for osteoporosis, offering evidence-based recommendations for the effective management of this chronic condition.
Ta-Wei Tai +46 more
doaj +1 more source
Advanced Science, EarlyView.This study identifies CRISPLD2 as a key protector against IVDD. By regulating ferroptosis through the CRISPLD2–miR‐548I–IL17A axis, CRISPLD2 maintains NPCs homeostasis and reduces oxidative stress. Restoring CRISPLD2 expression effectively alleviates disc degeneration and highlights a promising therapeutic strategy for discogenic low back pain ...
Yangyang Shi +11 more
wiley +1 more source
Nandrolone decanoate appears to increase bone callus formation in young adult rats after a complete femoral fracture [PDF]
Acta Cirúrgica Brasileira, 2017 Purpose: To evaluate the influence of nandrolone decanoate on fracture healing and bone quality in normal rats. Methods: Male rats were assigned to four groups (n=28/group): Control group consisting of animals without any intervention, Nandrolone ...
Ana Paula Franttini Garcia Moreno Guimarães +4 more
doaj +1 more source
Advanced Science, EarlyView.A developmentally inspired osteochondral construct integrates mechanical and metabolic dual gradients within a 3D‐printed platform. Human MSC spheroids are spatially directed to form cartilage–bone interfaces, enabling evaluation of regeneration without biochemical reagents and assessment of drug responses. This physiologically relevant, phase‐specific
Yurim Choi +11 more
wiley +1 more source
Medical Laboratory Journal, 2020 Background and Objectives: Liver is one of the vital organs of the human body. Antioxidants have been shown to play important roles in reducing liver injuries. The aim of this study was to examine the effects of gallic acid supplementation and resistance
Kazem Ranjbar +3 more
doaj
Severe Persistent Jaundice after the Abuse of an Anabolic Androgenic Steroid Analogue
The Korean Journal of Gastroenterology, 2020 Hepatic disorders with prominent cholestasis can be caused by a range of conditions, and anabolic androgenic steroids have been considered a cause of protracted cholestasis.
Hyun Gil Goh, Yoo Jin Lee, Tae Hyung Kim
doaj +1 more source
Anabolic Agents as New Treatment Strategy in Osteoporosis
, 2013 Osteoporosis is a systemic skeletal disease characterized by low bone mineral density (BMD), microarchitectural deterioration of bone tissue, and an increase in fracture risk [1]. Several drugs have been developed to treat osteoporosis: most of these are
T. Okman-Kilic, Cengiz Sagiroglu
semanticscholar +1 more source
Systematically Engineering for Efficient Production of 3‐Methyl‐1‐Butanol in Escherichia coli
Advanced Science, EarlyView.An integrated metabolic engineering strategy was established for high‐level 3‐methyl‐1‐butanol biosynthesis in Escherichia coli. Molecular dynamics‐guided semi‐rational engineering of dihydroxyacid dehydratase uncovered and relieved key catalytic bottlenecks, while adaptive laboratory evolution enhanced strain robustness.
Nanfei Geng +6 more
wiley +1 more source