Results 81 to 90 of about 3,709,556 (294)
Recommendations for the optimal use of bone forming agents in osteoporosis
Aging Clinical and Experimental ResearchBone forming agents, also known as anabolic therapies, are essential in managing osteoporosis, particularly for patients at very high-risk of fractures. Identifying candidates who will benefit the most from these treatments is crucial.
N. Veronese +23 more
semanticscholar +1 more source
Drug Testing and Analysis, EarlyView.New insights into drug metabolism, distribution, elimination, and detection assays for drugs and methods of sports doping published between 2024 and 2025 are critically reviewed and evaluated in context with the Prohibited List 2025 as established by the World Anti‐Doping Agency.
Mario Thevis, Tiia Kuuranne, Hans Geyer
wiley +1 more source
Identification of Metabolites of the Dietary Supplement Ingredient 5α‐Hydroxy‐Laxogenin
Drug Testing and Analysis, EarlyView.The biotransformation of the dietary supplement ingredient 5α‐hydroxy‐laxogenin was investigated using human HepG2 cells, the rat and in silico using the online software Next‐gen E‐Resource for Drug Discovery (NERDD). We identified five metabolites generated by the human HepG2 cells of which three and an additional mono‐hydroxylated metabolite were ...
Daniel Derwand +3 more
wiley +1 more source
Gene Expression in Hair Follicle Dermal Papilla Cells after Treatment with Stanozolol
Biomarker Insights, 2009 Doping with anabolic agents is a topic in sports where strength is crucial, e.g. sprinting, weight lifting and many more. Testosterone and its functional analogs are the drugs of choice taken as pills, creams, tape or injections to increase muscle mass ...
M. Reiter +3 more
doaj
Drug Testing and Analysis, EarlyView.The study developed a single Abnormal Steroid Profile Score (ASPS) to improve interpretation of the Athlete Biological Passport steroid module. Using Bayesian modelling and logistic regression, biomarker patterns from laboratory and doping control data successfully discriminated between doped and clean individuals, with improved classification ...
James G. Hopker +3 more
wiley +1 more source
Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss
iMetaMed, EarlyView.As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu +6 more
wiley +1 more source
Toxicological aspects of anabolics in food of animal origin
Croatian Journal of Food Science and Technology, 2011 Because of the profitability of the meat production in the livestock industry there were many cases of abuse of different substances with anabolic effect - stilbenes, stilbene derivatives, their salts and esters, antithyroid agents, natural and synthetic
B. Antolović +4 more
doaj
Move beyond free radical theory of aging
iMetaOmics, EarlyView.Free radicals play a dual, dose‐dependent role in aging. Low levels activate the key sensor adenosine 5'‐monophosphate‐activated protein kinase (AMPK), promoting cell survival mechanisms like autophagy and enhancing mitochondrial health. High levels, however, push AMPK to initiate cell death pathways, such as apoptosis. This positions AMPK as a central
Xiaofeng Dai, Meilan Hu, Ruohan Lyu
wiley +1 more source
Anabolic Agents: Adjuncts to Nutrition Support
Nutrition in Clinical Practice, 2004 Anabolic agents as adjuncts to nutrition support therapy have been used to improve malnutrition and establish anabolism. Growth hormone, insulin‐like growth factor, and anabolic steroids have been studied for their potential to reverse the catabolic process and promote anabolism.
openaire +4 more sources
Interdisciplinary Medicine, EarlyView.Illustration depicting the isolation of Dipsaci Radix derived extracellular vesicle‐like particles and their function in alleviating osteoporosis. (A) Extraction and characterization detection process of extracellular vesicle‐like particles derived from Dipsaci Radix roots. (B) Cell experiments in vitro, Dipsaci Radix derived extracellular vesicle‐like
Qing Zhao +12 more
wiley +1 more source