Results 121 to 130 of about 24,072 (312)
Biological Reviews, EarlyView.ABSTRACT Basal and standard metabolic rate (BMR and SMR) are cornerstones of physiological ecology and are assumed to be relatively fixed intrinsic properties of organisms that represent the minimum energy required to sustain life. However, this assumption is conceptually flawed. Many core maintenance processes underlying SMR are temporally partitioned
Helena Norman +4 more
wiley +1 more source
Muscle protein anabolism in advanced cancer patients: response to protein and amino acids support, and to physical activity [PDF]
, 2018 S. Antoun, Bruno Raynard
openalex +1 more source
Self‐Calibrating Ratiometric DNA Aptamer Probe for Quantitative ATP Imaging in Living Cells
Chemistry – A European Journal, EarlyView.We developed the RFA–ECHO probe, an internally calibrated ATP sensor that remains responsive across millimolar ATP levels. Its self‐correcting Cy5/ECHO ratio ensures accurate quantification independent of probe uptake. Compared with FRET‐based sensors, it yields a robust ratiometric shift, distinguishing high‐ATP cancer cells from normal ones, enabling
Yunsong Xu +5 more
wiley +1 more source
Improvement of EPO Transgene Detection From Polymeric Dried Blood Spots for Antidoping Application
Drug Testing and Analysis, EarlyView.This article presents an optimized protocol for gene doping detection. Starting from one spot DBS (20 μL), concentrated DNA was obtained and real‐time PCR parameters were adjusted for increased detection. Robust detection of 5000 copies/mL of transgene was validated for polymeric device TASSO M‐20.
Alexandre Marchand +2 more
wiley +1 more source
Drug Testing and Analysis, EarlyView.Well‐characterized, chemically synthesized molecules related to LGD‐4033 metabolism were used as analytical standards for the analysis of LGD‐4033 post‐administration urine samples. This approach offered further insights into LGD‐4033 metabolism, providing solid experimental proof for the structure of important previously reported metabolites and ...
Yiannis S. Angelis +5 more
wiley +1 more source
The Lysosomal v-ATPase-Ragulator Complex Is a Common Activator for AMPK and mTORC1, Acting as a Switch between Catabolism and Anabolism [PDF]
, 2014 Chen‐Song Zhang +19 more
openalex +1 more source
AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation [PDF]
, 2020 Jeanine L. Van Nostrand +9 more
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Investigations Into the Human Metabolism of Trestolone (7α‐Methyl‐19‐Nortestosterone)
Drug Testing and Analysis, EarlyView.As the known metabolites of 7α‐methyl‐19‐nortestosterone (MENT), M1 and M2, suffer from chromatographic issues under routine doping control conditions, the human metabolism of MENT was reinvestigated. From the numerous new metabolites detected, especially, M5 and M10 were identified as the most promising candidates to be implemented into routine ...
Thomas Piper +2 more
wiley +1 more source