Results 51 to 60 of about 29,332 (238)

Bioenergetic Materials for Tissue Regeneration: Modulating Metabolism to Promote Cellular Anabolism. [PDF]

Adv Sci (Weinh)
Bioenergetic materials (BEMs) modulate cellular metabolism to promote tissue regeneration. Their principal mechanisms of action include metabolic substrate supplementation, metabolic enzyme modulation, organelle transfer, electrical current regulation, redox homeostasis modulation, and oxygen tension modulation.
He Y, Wang Y, Gong JF, Lei Y, Jin F, Zhu W, Tuan RS, Li ZA.   +7 more
europepmc   +2 more sources

Stimulation of muscle anabolism by resistance exercise and ingestion of leucine plus protein

, 2009
Leucine is known to stimulate muscle protein synthesis and anabolism. However, evidence for the efficacy of additional leucine to enhance the response of muscle anabolism to resistance exercise and protein ingestion is unclear.
Wolfe, RR, Aarsland, Asle A, Elliot, TA, Elliott, Tabatha A, Ferrando, Arny A, Elliott, TA, Ferrando, AA, Aarsland, AA, Tipton, Kevin, Wolfe, Robert R   +9 more
core   +1 more source

TOLLIP Inhibits Psoriasis Progression via Suppressing PKM2‐Mediated Glycolysis in Keratinocytes

Advanced Science, EarlyView.
In this study, we identify TOLLIP as a critical regulator of psoriasis pathogenesis through its modulation of glycolytic metabolism. Our findings establish the TOLLIP‐PKM2‐glycolysis axis as a key mechanism linking metabolic reprogramming to psoriasis pathogenesis, and propose TOLLIP as a promising therapeutic target.
Xiuhuan Jiang, Guoying Miao, Na Shen, Qingxia Han, Xiaoru Han, Zichang Qiao, Kexin Feng, Zhuo Tan, Yaguang Wang, Xiuhua Liu, Chen Wu, Zhenzhen Yan   +11 more
wiley   +1 more source

Ischemic nucleotide breakdown increases during cardiac development due to drop in adenosine anabolism/catabolism ratio [PDF]

, 1990
Our earlier work on reperfusion showed that adult rat hearts released almost twice as much purine nucleosides and oxypurines as newborn hearts did [Am J Physiol 254 (1988) H1091].
Schoutsen, B., Huizer, T. (Tom), Jong, J.W. (Jan Willem) de, Keijzer, E. (Elisabeth)   +3 more
core   +1 more source

IL-1ß and BMPs - Interactive players of cartilage matrix degradation and regeneration [PDF]

European Cells & Materials, 2006
Intact human adult articular cartilage is central for the functioning of the articulating joints. This largely depends on the integrity of its extracellular matrix, given the high loading forces during movements in particular in the weight-bearing joints.
T Aigner, S Soeder, J Haag
doaj  

EFFECT OF LEVELS OF ANIMAL DIETARY PROTEIN AND PROBIOTIC ADDITIVES (SACCHAROMYCES CEREVISIAE AND BACILLUS SUBTILIS) ON INSULIN, TSH AND GROWTH HORMON OF AWASSI SHEEP

Al-Qadisiyah Journal For Agriculture Sciences, 2020
To maintain the body on its metabolic activities, including catabolic and anabolic processes, it needs tools. Insulin, thyroxine, growth hormone and other hormones are considered the tools that contribute to regulate metabolism in living organism.
A. F. Al-Abedi, A. A. Saeed, K. S. Al-Huosyney   +2 more
doaj   +1 more source

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

Advanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li, Hui Yuan, Honglei Xiao, Xiaodong Liu, Wenguo Cui   +4 more
wiley   +1 more source

An oral essential amino acid-carbohydrate supplement enhances muscle protein anabolism after resistance exercise

, 2000
This study was designed to determine the response of muscle protein to the bolus ingestion of a drink containing essential amino acids and carbohydrate after resistance exercise.
Steven E. Wolf, Kevin D. Tipton, Miller, Sharon L, Blake B. Rasmussen, Rasmussen, Blake B, Sharon L. Miller, Robert R. Wolfe, Tipton, Kevin, Wolfe, Robert R, Wolf, Steven E   +9 more
core   +1 more source

Influencia de la infección por VIH/sida sobre algunos indicadores bioquímicos del estado nutricional

Biomédica: revista del Instituto Nacional de Salud, 2002
Con el objetivo de analizar la influencia de la infección por el VIH y el estadio clínico de la enfermedad sobre indicadores bioquímicos del estado nutricional del individuo, se estudió un grupo de individuos infectados y clasificados en diferentes ...
Maritza E. Linares, J. F. Bencomo, L. E. Pérez, O. Barrera   +3 more
doaj   +1 more source

The IRE1‐XBP1s Axis Drives Inflammatory Osteolysis by Regulating a 5‐HT Dependent Endogenous Anti‐Autophagy Mechanism

Advanced Science, EarlyView.
A previously unrecognized IRE1‐XBP1s‐Slc6a4 signaling axis links endoplasmic reticulum stress to serotonin metabolism, autophagy, and inflammatory osteoclastogenesis. By promoting intracellular serotonin uptake and reducing endogenous 3‐methyladenine accumulation, this pathway accelerates inflammatory bone destruction and provides a promising ...
Pengchao Yang, Binxiang Zhu, Yuzhi He, Yang Tian, Honglei Kang, Shian Hu, Pengju Wang, Yong Xu, Zhuowei Lei, Peijun Qi, Hao Yang, Yang Lin, Yimin Dong, Feng Li, Hanfeng Guan   +14 more
wiley   +1 more source