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Lipoxygenase Inhibitory Activity of Anacardic Acids

Journal of Agricultural and Food Chemistry, 2005
6[8'(Z)-pentadecenyl]salicylic acid, otherwise known as anacardic acid (C15:1), inhibited the linoleic acid peroxidation catalyzed by soybean lipoxygenase-1 (EC 1.13.11.12, type 1) with an IC50 of 6.8 microM. The inhibition of the enzyme by anacardic acid (C15:1) is a slow and reversible reaction without residual activity.
Tae Joung, Ha, Isao, Kubo
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Syntheses of anacardic acids and ginkgoic acid

Tetrahedron, 1987
Abstract Syntheses of two anacardic acids [6-pentadecyl- and 6-(10-pentadecenyl) salicylic acid], inhibitors of prostaglandin synthetase and of the growth of certain insects, and ginkgoic acid via directive metallation is reported.
Yoshiro Yamagiwa   +5 more
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Antioxidant activity of anacardic acids

Food Chemistry, 2006
Abstract Anacardic acids, 6-pentadec(en)ylsalicylic acids isolated from the cashew Anacardium occidentale L. (Anacardiaceae) nut and apple, were found to possess preventive antioxidant activity while salicylic acid did not show this activity. These anacardic acids prevent generation of superoxide radicals by inhibiting xanthine oxidase (EC 1.1.3.22,
Isao Kubo   +3 more
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Synthesis of anacardic acids in seeds of ginkgo biloba

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1976
Anacardic (6-alkylsalicylic) acids and common lipids are efficiently synthesized by immature seeds of Ginkgo biloba. The seeds were incubated with 14C-labeled acetic, malonic and palmitoleic acids, glucose, and other potential precursors. Levels of 14C in common lipids and in anacardic acids, and the distribution of 14C in anacardic acids were ...
J L, Gellerman   +2 more
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Synthesis of Analogues of Biologically Active Anacardic Acids.

ChemInform, 2002
AbstractFor Abstract see ChemInform Abstract in Full Text.
Ivan R. Green, Felismino E. Tocoli
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ChemInform Abstract: Synthesis of Anacardic Acids.

ChemInform, 1996
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
R. ZEHNTER, H. GERLACH
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SYNTHESIS OF AN UNNATURAL ANACARDIC ACID ANALOGUE

Synthetic Communications, 2002
The unnatural E isomer of anacardic acid 7 has been synthesized employing the following key steps: Swern oxidation of a diastereoisomeric mixture of β-hydroxyphosphine oxides 13a/b to the corresponding ketone 14 followed by stereospecific reduction to the pure threo isomer 13b which upon treatment with sodium hydride underwent trans elimination to ...
Ivan R. Green, Felismino E. Tocoli
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Fatty acid incorporation in the biosynthesis of anacardic acids of geraniums

Phytochemistry, 1990
Abstract Geraniums, Pelargonium xhortorum, have been shown to possess tall glandular trichomes which secrete anacardic acids, a viscous, sticky exudate which provides defence against small pest species. Pest-resistant geraniums possess primarily C 22 - and C 24 -unsaturated (ω-5) anacardic acids with lesser amounts of the C 22 - and C 24 -saturated ...
Donald S. Walters   +2 more
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Synthesis of anacardic acids by nucleophilic substitution on 2-aryloxazolines

Tetrahedron Letters, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Julio A. Seijas   +3 more
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Efficient synthesis of anacardic acid analogues and their antibacterial activities

Bioorganic & Medicinal Chemistry Letters, 2013
Anacardic acid derivatives exhibit a broad range of biological activities. In this report, an efficient method for the synthesis of anacardic acid derivatives was explored, and a small set of salicylic acid variants synthesised retaining a constant hydrophobic element (a naphthyl tail). The naphthyl side chain was introduced via Wittig reaction and the
Mamidyala, Sreeman K.   +4 more
openaire   +5 more sources

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