Results 171 to 180 of about 3,472 (209)

Structure-antibacterial activity relationships of anacardic acids

Journal of Agricultural and Food Chemistry, 1993
A series of anacardic acids possessing different side-chain lengths were synthesized, and their antimicrobial activity was tested. In the case against Staphylococcus aureus, the anacardic acid having the C 10 alkyl side chain was most active, while against Propionibacterium acnes, Streptococcus mutant, and Brevibacterium ammoniagenes, the anacardic ...
Isao. Kubo, Hisae. Muroi, Masaki. Himejima, Yoshiro. Yamagiwa, Hiroyuki. Mera, Kimihiro. Tokushima, Shigeo. Ohta, Tadao. Kamikawa   +7 more
openaire   +1 more source

SYNTHESIS OF AN UNNATURAL ANACARDIC ACID ANALOGUE

Synthetic Communications, 2002
The unnatural E isomer of anacardic acid 7 has been synthesized employing the following key steps: Swern oxidation of a diastereoisomeric mixture of β-hydroxyphosphine oxides 13a/b to the corresponding ketone 14 followed by stereospecific reduction to the pure threo isomer 13b which upon treatment with sodium hydride underwent trans elimination to ...
Ivan R. Green, Felismino E. Tocoli
openaire   +1 more source

Synthesis of anacardic acids in seeds of ginkgo biloba

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1976
Anacardic (6-alkylsalicylic) acids and common lipids are efficiently synthesized by immature seeds of Ginkgo biloba. The seeds were incubated with 14C-labeled acetic, malonic and palmitoleic acids, glucose, and other potential precursors. Levels of 14C in common lipids and in anacardic acids, and the distribution of 14C in anacardic acids were ...
J L, Gellerman, W H, Anderson, H, Schlenk   +2 more
openaire   +2 more sources

Antimicrobial effects of anacardic acids

Canadian Journal of Microbiology, 1969
Anacardic acids (6-alkylsalicylic acids) inhibited metabolism of Streptococcus faecalis, Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens, Gyrodinium cohnii, Euglena gracilis and a white mutant of it, Neurospora crassa, Penicillium griseofulvum, Saccharomyces cerevisiae, and Candida utilis. The Gram-positive B. subtilis and S.
J L, Gellerman, N J, Walsh, N K, Werner, H, Schlenk   +3 more
openaire   +2 more sources

Synthesis of anacardic acids by nucleophilic substitution on 2-aryloxazolines

Tetrahedron Letters, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Julio A. Seijas, M. Pilar Vazquez‐Tato, M. Montserrat Martinez, Veronica Santiso   +3 more
openaire   +1 more source

Anti-Helicobacter pylori activity of anacardic acids from Amphipterygium adstringens

Journal of Ethnopharmacology, 2007
Amphipterygium adstringens (Schltdl.) Standl. (Anacardiaceae) is widely used in traditional Mexican medicine for the treatment of gastritis and ulcers. In this work, we studied the anti-Helicobacter pylori activity of its bark, this Gram-negative bacterium is considered the major etiological agent of chronic active gastritis and peptic ulcer disease ...
Israel, Castillo-Juárez, Fausto, Rivero-Cruz, Heliodoro, Celis, Irma, Romero   +3 more
openaire   +2 more sources

Efficient synthesis of anacardic acid analogues and their antibacterial activities

Bioorganic & Medicinal Chemistry Letters, 2013
Anacardic acid derivatives exhibit a broad range of biological activities. In this report, an efficient method for the synthesis of anacardic acid derivatives was explored, and a small set of salicylic acid variants synthesised retaining a constant hydrophobic element (a naphthyl tail). The naphthyl side chain was introduced via Wittig reaction and the
Mamidyala, Sreeman K., Ramu, Soumya, Huang, Johnny X., Robertson, Avril A. B., Cooper, Matthew A.   +4 more
openaire   +3 more sources

Anacardic acid derived salicylates are inhibitors or activators of lipoxygenases

Bioorganic & Medicinal Chemistry, 2012
Lipoxygenases catalyze the oxidation of unsaturated fatty acids, such as linoleic acid, which play a crucial role in inflammatory responses. Selective inhibitors may provide a new therapeutic approach for inflammatory diseases. In this study, we describe the identification of a novel soybean lipoxygenase-1 (SLO-1) inhibitor and a potato 5-lipoxygenase (
Wisastra, Rosalina, Ghizzoni, Massimo, Boltjes, Andre, Haisma, Hidde J., Dekker, Frank J.   +4 more
openaire   +3 more sources

Design and evaluation of anacardic acid derivatives as anticavity agents

European Journal of Medicinal Chemistry, 2008
On the basis of antibacterial anacardic acids, 6-pentadecenylsalicylic acids, isolated from the cashew apple, Anacardium occidentale L. (Anacardiaceae), a series of 6-alk(en)ylsalicylic acids were synthesized and tested for their antibacterial activity against Streptococcus mutans ATCC 25175.
Ivan R, Green, Felismino E, Tocoli, Sang Hwa, Lee, Ken-ichi, Nihei, Isao, Kubo   +4 more
openaire   +2 more sources

Sodium hyaluronate microcapsules to promote antitumor selectivity of anacardic acid

International Journal of Biological Macromolecules
Anacardic acid (AA) is a phenolic lipid extracted from cashew nutshell liquid that has antitumor activity. Given the high hydrophobicity of this compound and aiming to create efficient vehicle for its administration in aqueous systems, the objective of the present work was to develop a microcapsule (MCAA) by spray dryer technique, based on the ...
Marlon E P, Rosa, Louhana M, Rebouças, Samuel P D, Marques, Larissa M R, Silva, Fernando E T, Cunha, Pedro M S, Costa, David A, de Assis, Kamilla B, Silveira, Celli R, Muniz, Maria T S, Trevisan, Cláudia, Pessoa, Nágila M P S, Ricardo   +11 more
openaire   +2 more sources