Results 121 to 130 of about 47,691 (279)

The Complex World of Toothpaste Diversity, Meeting Patient Clinical Needs. An Umbrella Review

International Journal of Dental Hygiene, EarlyView.
ABSTRACT Background Amidst numerous recent advancements in toothpaste formulations and active ingredients, some clinicians may believe all toothpastes are similar despite differences in their active ingredients and corresponding clinical application.
Jeanie Suvan, Crystal Marruganti
wiley   +1 more source

Male genital lichen sclerosus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Male genital lichen sclerosus is driven by chronic, occluded exposure of susceptible genital epithelium to urine, rather than infection or autoimmunity. This review synthesizes clinical, anatomical and molecular evidence showing how microincontinence and occlusion initiate inflammation, fibrosis and carcinogenesis, and explains the curative effect of ...
Georgios Kravvas, Rory Barry, Richard E. Watchorn, Christopher B. Bunker   +3 more
wiley   +1 more source

Pathogenesis of hidradenitis suppurativa: From susceptibility to chronicity

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review describes hidradenitis suppurativa as a heterogeneous disorder in which genetic susceptibility, epithelial dysfunction, environmental exposures, immune activation and microbial ecology converge differently across patients and disease stages.
Kelsey R. van Straalen, Nisha S. Chandran, Jean M. Fletcher, Evangelos J. Giamarellos‐Bourboulis, Elia Rosi, Gregor B. E. Jemec   +5 more
wiley   +1 more source

Sepsis and septic shock caused by Porphyromonas gingivalis: a case report

Journal of Oral Microbiology
Background Porphyromonas gingivalis is a predominant pathogen in periodontitis and is closely associated with the progression of chronic obstructive pulmonary disease (COPD).Objective This case report aims to describe a case of sepsis caused by P ...
Meifang Lin, Guang Yang, Cong Shen, Yinglun Xiao, Cha Chen, Xuan Zhang   +5 more
doaj   +1 more source

Hidradenitis suppurativa skin microbiome: In‐depth analysis and modulation by systemic therapies

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Hidradenitis suppurativa skin exhibits profound dysbiosis, characterized by the depletion of homeostatic commensals and expansion of anaerobic pathogens. Longitudinal evaluation reveals that while systemic antibiotics successfully reverse HS dysbiosis, biologics (adalimumab and secukinumab) fail to clear pathogens despite clinical healing.
Yacine Amar, Diana Baumann, Sebastian Niedermeier, Rafaela L. Silva, Susanne Walch, Michael Schloter, Martin Köberle, Tilo Biedermann, Thomas Volz   +8 more
wiley   +1 more source

mGem: Faecalibacterium, an important protector of gut health

mBio
Faecalibacterium is among the most abundant bacterial genera in the healthy human colon, comprising approximately 10–15% of the total gut microbiota. Species within this genus ferment complex carbohydrates, including pectin, to produce butyrate, a short ...
Carlos Sabater, Xenia Vázquez, Sylvia H. Duncan   +2 more
doaj   +1 more source

High-throughput cultivation and isolation of environmental anaerobes using selectively permeable hydrogel capsules

Over the past two decades, metagenomics has greatly expanded our understanding of microbial phylogenetic and metabolic diversity. However, most microbial taxa remain uncultured, hindering research and biotechnological applications.
Meibom, Karin Lederballe, Titus, Matteo, Sallet, Hugo, Jacquemin, Nicolas, Calvo, Marion, Bernier-Latmani, Rizlan   +5 more
core   +1 more source

Obesity‐associated transcriptomic remodelling in hidradenitis suppurativa and treatment response

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review highlights that adiposity systemically primes HS through adipokine dysregulation and insulin resistance, contributing to lesional metabolic reprogramming and perilesional barrier dysfunction. Current evidence indicates that obesity exacerbates disease severity and attenuates responses to biologic therapies, supporting the classification of ...
Sahil Kapur, Xzaviar K. Solone, Randy Mi, Kermanjot S. Sidhu, Meyer Gershater, Jeffrey Cruz, Iltefat Hamzavi, Indra Adrianto, Li Zhou, Qing‐Sheng Mi   +9 more
wiley   +1 more source

Anaerobic antibiotic exposure and risk of maculopathy: a nationwide dual design study

Frontiers in Pharmacology
The pathogenesis of maculopathy remains incompletely understood, and emerging evidence implicates the gut–eye axis in retinal and macular diseases.
Jiyeon Park, Seunghyun Cheon, Yu-Seon Choi, Jiyeong Kim, Seong Joon Ahn, Jee-Eun Chung   +5 more
doaj   +1 more source

Individualized Oral Health Care for Dysphagic, Care‐Dependent Patients With Acquired Brain Injury: An Exploratory Predefined Subgroup Analysis of a Cluster Nonrandomized Controlled Trial

Journal of Oral Rehabilitation, EarlyView.
This graphical abstract summarizes an exploratory predefined subgroup analysis of dysphagic, care‐dependent adults with acquired brain injury undergoing inpatient neurorehabilitation. Three wards implemented standard oral care, while three wards implemented the structured individualized MOHIT protocol.
Mohit Kothari
wiley   +1 more source