Results 11 to 20 of about 836 (177)
Associations Between the Gut Microbiota and Physical Activity, Sedentary Behaviour and Physical Function in Community-Dwelling Older Adults. [PDF]
J Aging ResGut microbiota (GM) plays a crucial role in maintaining health through metabolic, endocrine and immune functions. With ageing, shifts in GM composition, characterised by increased pathogenic and decreased health‐promoting bacteria, contribute to dysbiosis, which is linked to several age‐related diseases.
Ramos C +8 more
europepmc +2 more sources
Influence of Gut Microbiota on Response to Immune Check Point Inhibitors in MASLD Patients With HCC: Unraveling the Connection. [PDF]
Cancer MedABSTRACT Immune checkpoint inhibitors (ICIs) have emerged as a promising treatment for various cancers, including advanced hepatocellular carcinoma (HCC). However, a significant proportion of patients with HCC, particularly those with metabolic dysfunction‐associated liver disease (MASLD), exhibit resistance to ICI therapy.
Elsheikh M +9 more
europepmc +2 more sources
Gut Microbiota and Hepatocellular Carcinoma: Metabolic Products and Immunotherapy Modulation. [PDF]
Cancer MedABSTRACT Background The relationship between hepatocellular carcinoma (HCC) and gut microbiota has gained attention for its impact on HCC immunotherapy. Methods Key gut microbial metabolites, including bile acids, toll‐like receptor 4, short‐chain fatty acids, and bacterial toxins, contribute to HCC progression and influence immune responses through ...
Xiao K, Li K, Xiao K, Yang J, Zhou L.
europepmc +2 more sources
Ethanologenesis from glycerol by the gut acetogen Blautia schinkii
Environmental Microbiology, Volume 25, Issue 12, Page 3577-3591, December 2023., 2023 We analysed the glycerol metabolism of Blautia schinkii with physiological, biochemical and gene expression studies. At low glycerol concentrations acetate and ethanol are formed in equal amounts. However, at high glycerol concentrations only ethanol is formed presenting a novel feature of human gut bacteria: Homoethanologenesis from glycerol ...
Raphael Trischler +3 more
wiley +1 more source
Integrative Zoology, Volume 18, Issue 6, Page 1089-1104, November 2023., 2023 The Tibetan wild ass is the only wild Perissodactyla herbivore in the Qinghai‐Tibet Plateau. Abstract Ex situ conservation is the main method for the protection of endangered wildlife. To explore the effect of ex situ conservation on the gut microbiota of the kiang (Equus kiang), metagenomic sequencing combined with bioinformatics analysis was used to ...
Hongmei GAO +7 more
wiley +1 more source
Long‐term hypercaloric diet exacerbates metabolic liver disease in PNPLA3 I148M animals
Liver International, Volume 43, Issue 8, Page 1699-1713, August 2023., 2023 Abstract Background & Aims Nonalcoholic fatty liver disease (NAFLD) is a major health burden associated with the metabolic syndrome leading to liver fibrosis, cirrhosis and ultimately liver cancer. In humans, the PNPLA3 I148M polymorphism of the phospholipase patatin‐like phospholipid domain containing protein 3 (PNPLA3) has a well‐documented impact on
Huan Su +17 more
wiley +1 more source
Safety and quality assessment of street‐vended barbecue chicken samples from Faisalabad, Pakistan
Food Science &Nutrition, Volume 11, Issue 2, Page 930-939, February 2023., 2023 • Control sample exhibited a better nutritional profile, and quality characteristics and also appeared to be microbiologically safe than street‐vended barbecue chicken.• Higher concentrations of highly toxic and essential metals found in barbecue chicken than their safe limits.• Results suggested the dire need of continual inspection and monitoring of ...
Ayesha Ali +9 more
wiley +1 more source
Environmental Microbiology, Volume 24, Issue 12, Page 6411-6425, December 2022., 2022 Abstract Self‐transferable plasmids of the incompatibility group P‐1 (IncP‐1) are considered important carriers of genes for antibiotic resistance and other adaptive functions. In the laboratory, these plasmids have a broad host range; however, little is known about their in situ host profile.
Hao‐Yu Lo +6 more
wiley +1 more source
The FEBS Journal, Volume 289, Issue 23, Page 7582-7604, December 2022., 2022 RedR1 and RedR2 are bacterial enhancer‐binding proteins than only differ in 17 residues (labelled orange and lilac) but are controlled through opposite mechanisms: RedR2 is constitutive and kept inactive by binding the membrane protein BtdS. RedR1 is negatively controlled by its N‐terminal domain.
Daniel Pacheco‐Sánchez +3 more
wiley +1 more source
Cycling of reduced phosphorus compounds in soil and potential impacts of climate change
European Journal of Soil Science, Volume 72, Issue 6, Page 2517-2537, November 2021., 2021 Abstract Soil phosphorus (P) remains an ever‐increasing topic of importance, notably for its key role as a nutrient for driving food production but with parallel concerns over damaging water quality, all against a backdrop of uncertainty of long‐term rock phosphate supplies.
Anchen Kehler +3 more
wiley +1 more source