Results 251 to 260 of about 105,619 (308)

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth   +5 more
wiley   +1 more source

The Role of Oxidative Stress in Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon   +3 more
wiley   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

open access: yesJournal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima   +3 more
wiley   +1 more source

Autoimmunity and Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga   +2 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

open access: yesJournal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini   +3 more
wiley   +1 more source

Redundant and Flexible Electron Transfer Pathways Underlie MsrPQ‐Mediated Repair of Oxidized Periplasmic Proteins

open access: yesMolecular Microbiology, EarlyView.
This study investigates in vivo the role of the flavin reductase Fre as an electron supplier to the periplasmic methionine sulfoxide reductase system MsrPQ. ABSTRACT The MsrPQ system is essential for the repair of oxidized methionine residues in periplasmic proteins, ensuring bacterial resistance to oxidative stress and envelope integrity.
Laurent Loiseau, Benjamin Ezraty
wiley   +1 more source

Faecal Attraction: 40 Years of Research in Gut Microbiology

open access: yesNutrition Bulletin, EarlyView.
ABSTRACT This article summarises the 2025 British Nutrition Foundation Annual Lecture given on 25/11/25. It overviews aspects of research in anaerobic microbiology, principally involving the human gut. Until October 2025, Gibson was Professor of Food Microbiology at the University of Reading.
Glenn R. Gibson
wiley   +1 more source

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