Results 211 to 220 of about 446,285 (290)
Integrative Zoology, EarlyView.Metagenomic sequencing was used to analyze fecal microbiota of captive male forest musk deer (FMD) from the Sichuan Institute of Musk Deer Breeding across ages and musk‐secreting periods. Gut microbiota was generally stable and dominated by Firmicutes, while age and musk secretion shaped microbial composition and function, with musk collection linked ...
Jiuyan Jiang +17 more
wiley +1 more source
Integrative Zoology, EarlyView.Seasonal variation significantly reshaped gut microbiota composition in migratory passerine species, whereas the resident species Suthora webbiana showed no clear seasonal shift. Species with similar migratory behaviors exhibited consistent seasonal patterns in their core gut microbiota.
Jundong Duan +11 more
wiley +1 more source
British Journal of Haematology, EarlyView.Summary Microbial metabolites are key regulators of host immunity, yet their functional impact in chronic lymphocytic leukaemia (CLL) remains unclear. Following up on our earlier observations of microbiome dysbiosis in CLL, we performed predictive metabolic profiling based on 16S ribosomal RNA (rRNA) sequencing of oral and stool samples collected from ...
Monika Szelest +15 more
wiley +1 more source
Gut microbiota as a novel therapeutic target for eating disorders and obesity
British Journal of Pharmacology, EarlyView.The graphical abstract highlights the bidirectional interaction between the gut microbiota and central homeostatic and hedonic mechanisms regulating food intake, which contributes to overweight and obesity. It also illustrates emerging microbiota‐based biomarkers and therapeutic strategies (including prebiotics, probiotics, postbiotics, synbiotics and ...
Solveiga Samulėnaitė +5 more
wiley +1 more source
Cell Proliferation, EarlyView.The lichen‐derived metabolite methyl 4‐O‐demethylbarbatate (Me‐4‐O‐DBA) suppresses glioma stemness, motility, and metabolic plasticity through inhibition of HIF‐1α signaling and synergistically enhances temozolomide activity, highlighting a potential strategy to target stemness‐driven therapeutic resistance in glioma.
Rui Zhou +8 more
wiley +1 more source
Lactate and Lactylation: What We Know and What We Expect in Tumour Progression
Cell Proliferation, EarlyView.Lactate and lactylation in cancer cells have been shown to accelerate tumour development in various ways, including stemness generation, metabolic dysregulation, cell death, chemotherapy resistance, and cell cycle disorder. In addition, lactate and lactylation promote angiogenesis and create an immunosuppressive microenvironment, which promotes tumour ...
Qi Zhang, Zhenzhen Han, Youjia Duan
wiley +1 more source
Common pathways and outliers in glucose catabolism across Trypanosomatidae
The FEBS Journal, EarlyView.Trypanosomatid parasites, including Trypanosoma sp., Leishmania sp., Phytomonas sp., and Vickermania sp., share a common motif: a metabolism built around the glycosome, a unique peroxisome‐derived organelle housing the first steps of glycolysis. Yet, these organisms have evolved remarkably diverse strategies to catabolize glucose, excreting distinct ...
Fred R. Opperdoes +5 more
wiley +1 more source
A comprehensive study on ferredoxin isoforms in the cyanobacterium Synechocystis sp. PCC 6803
The FEBS Journal, EarlyView.Ferredoxins are small FeS cluster‐containing proteins that play a central role in distributing electrons within the cell. The cyanobacterium Synechocystis sp. PCC 6803 contains several ferredoxin isoforms and their biophysical properties (UV/Vis and EPR spectra, Em potential), expression patterns, and interactions with the electron donors photosystem I
Marko Boehm +14 more
wiley +1 more source
UbiB proteins mediate an ATP‐dependent decarboxylation step in bacterial ubiquinone biosynthesis
The FEBS Journal, EarlyView.UbiB proteins are atypical protein kinase‐like enzymes essential for ubiquinone biosynthesis. Here, we demonstrate that bacterial UbiB proteins catalyze the O2‐dependent decarboxylation of ubiquinone precursors, a process linked to their ATPase activity.
Katayoun Kazemzadeh +12 more
wiley +1 more source
Delivering Sulfate to LNAPL Body for Enhanced Source Zone Depletion (ESZD)
Groundwater Monitoring &Remediation, EarlyView.Abstract This field pilot study evaluates the feasibility of applying sulfate to a light non‐aqueous phase liquid (LNAPL) body for achieving enhanced source zone depletion (ESZD) at a refinery site. Two rounds of gypsum land application (GLA) delivered sulfate to an 8000 ft2 area encompassing LNAPL‐containing monitoring wells MW‐2 and MW‐3, while MW‐1 ...
Ravi Kolhatkar +2 more
wiley +1 more source