Results 91 to 100 of about 345,476 (333)
A fast ethanol assay to detect seed deterioration [PDF]
, 2012 The most common way to test seed quality is to use a simple and reliable but time- and space-consuming germination test. In this paper we present a fast and simple method to analyse cabbage seed deterioration by measuring ethanol production from ...
Buckley, W.T. +5 more
core +2 more sources
Lactate activates HIF-1 in oxidative but not in Warburg-phenotype human tumor cells. [PDF]
PLoS ONE, 2012 Cancer can be envisioned as a metabolic disease driven by pressure selection and intercellular cooperativeness. Together with anaerobic glycolysis, the Warburg effect, formally corresponding to uncoupling glycolysis from oxidative phosphorylation ...
Christophe J De Saedeleer +5 more
doaj +1 more source
Advanced Science, EarlyView.Herpes Simplex Virus Type 1 (HSV‐1) infection triggers metabolic reprogramming in corneal cells, shifting from mitochondrial respiration to aerobic glycolysis with marked upregulation of Hexokinase‐2 (HK2). This study identifies HK2 as a therapeutic target: inhibiting HK2 with lonidamine significantly reduces viral replication and promotes corneal ...
Dan Jiang +9 more
wiley +1 more source
Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells. [PDF]
, 2017 Glioblastoma (GBM) stem cells (GSCs) reside in both hypoxic and vascular microenvironments within tumors. The molecular mechanisms that allow GSCs to occupy such contrasting niches are not understood.
Barcellos-Hoff, Mary Helen +20 more
core +1 more source
The effects of hyperglycaemic hypoxia on rectification in rat dorsal root axons [PDF]
, 1994 1. Electrotonic responses to 150 ms current pulses were recorded from isolated rat dorsal roots incubated for at least 3 h with either normal (5 mM) or high (25 mM) D-glucose solutions, and with either normal (25 mM) or low (5 mM) bicarbonate ...
Bostock, Hugh +2 more
core +2 more sources
Advanced Science, EarlyView.Sleep deprivation triggers systemic immune activation characterized by neutrophil accumulation and cytokine release. This study reveals a conserved metabolic‒epigenetic mechanism whereby lactate‐induced H3K18 lactylation upregulates RORα expression, promoting neutrophilic inflammation.
Ren Zhou +15 more
wiley +1 more source
The use of the ethanol pathway in goldfish Carassius auratus (L.) following anoxia [PDF]
, 2001 Goldfish (Carassius auratus) were subjected, for a period of 6 weeks, to 2h progressive hypoxia followed by 6h anoxia in closed respirometers at 15 degree C.
Aleleye-Wokoma, L.P.
core
Mass conserved elementary kinetics is sufficient for the existence of a non-equilibrium steady state concentration [PDF]
, 2012 Living systems are forced away from thermodynamic equilibrium by exchange of mass and energy with their environment. In order to model a biochemical reaction network in a non-equilibrium state one requires a mathematical formulation to mimic this forcing.
Fleming, Ronan M. T., Thiele, Ines
core +2 more sources
Modelling energy metabolism dysregulations in neuromuscular diseases: A case study of calpainopathy
HeliyonBiological modelling helps understanding complex processes, like energy metabolism, by predicting pathway compensations and equilibrium under given conditions.
Camille Siharath +2 more
doaj +1 more source
Microwave‐Activated Bacterial Biorobot for Multimodal Cancer Therapy
Advanced Science, EarlyView.An Escherichia coli bacterial biorobot is engineered for localized microwave activation in cancer therapy. Upon activation at tumor sites, the biorobot releases glucose oxidase, inducing tumor cell death via glucose depletion and H2O2 generation catalyzed by Cu2O.
Huilan Zhuang +9 more
wiley +1 more source