Results 161 to 170 of about 341,458 (322)

Photodynamic therapy enhances the cytotoxicity of temozolomide against glioblastoma via reprogramming anaerobic glycolysis

, 2023
Yongzhe Li, Dan Wang, Zhaoxia Zhang, Yunzhi Wang, Zichen Zhang, Zibin Liang, Fei Liu, Lei Chen   +7 more
openalex   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

Cell Proliferation, EarlyView.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan, Zhou Chen, Yuhua Zhang, Wenjie Sun, Lifei Li, Xia Huang   +5 more
wiley   +1 more source

Serum proteomic and metabolomic analyses from patients with IBD identify biological pathways associated with treatment success with anti‐integrin therapy

Immunology &Cell Biology, EarlyView.
In this article, we have analyzed the serum proteome and metabolome in inflammatory bowel disease patients being treated with the anti‐α4β7 integrin therapeutic agent vedolizumab. The pretreatment biomarker profiles, as well as changes in biomarker profiles during treatment, identified likely pro‐inflammatory pathways associated with treatment response.
John D Rioux, Gabrielle Boucher, Anik Forest, Bertrand Bouchard, Lise Coderre, Caroline Daneault, Isabelle Robillard Frayne, Julie Thompson Legault, Alain Bitton, Ashwin Ananthakrishnan, Sylvie Lesage, Ramnik J Xavier, Christine Des Rosiers, iGenoMed Consortium, Alain Bitton, Gabrielle Boucher, Guy Charron, Christine Des Rosiers, Anik Forest, Philippe Goyette, Sabine Ivison, Lawrence Joseph, Rita Kohen, Jean Lachaine, Sylvie Lesage, Megan Levings, John D. Rioux, Julie Thompson Legault, Luc Vachon, Sophie Veilleux, Brian White‐Guay   +30 more
wiley   +1 more source

ATP produced by anaerobic glycolysis is essential for enucleation of human erythroblasts [PDF]

, 2019
Tatsufumi Goto, Kumi Ubukawa, Isuzu Kobayashi, Kotomi Sugawara, Ken Asanuma, Yumi Sasaki, Yong‐Mei Guo, Naoto Takahashi, Kenichi Sawada, Hideki Wakui, Wataru Nunomura   +10 more
openalex   +1 more source

Atrial Fibrillation (AF) and Heart Failure With Preserved Ejection Fraction (HFpEF): Advances and Challenges

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT This state‐of‐the‐art review is based on the Philippe Coumel Lecture in 2024 (Figure 1). It highlights the confluence of two major cardiovascular epidemics, atrial fibrillation and heart failure, with preserved ejection fraction. In these conditions, advances in electrophysiology and heart failure physiology are intertwined and are integrated ...
Sanjeev Saksena, April Slee, Ranghadham Nagarakanti, Atul Prakash   +3 more
wiley   +1 more source

Evolutionary dynamics of the Warburg effect: Glycolysis as a collective action problem among cancer cells. [PDF]

, 2013
Archetti, Marco
core   +1 more source

Compositional and Metabolomic Shifts of the Gut Microbiome in Alcohol‐Related Liver Disease

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Alcohol‐related liver disease (ALD) is a major global health concern characterized by steatosis and liver inflammation due to chronic alcohol consumption. Emerging evidence suggests that ALD is not solely a liver pathology but also involves dysfunction of the gut‐liver axis, where alterations in the gut microbiota play a significant role ...
Cheng‐Hao Kuo, Emad El‐Omar, Cheng‐Yen Kao, Jaw‐Town Lin, Chun‐Ying Wu   +4 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Whole‐Genome Sequencing and Phenotyping Reveal Specific Adaptations of Lachancea thermotolerans to the Winemaking Environment

Molecular Ecology, EarlyView.
ABSTRACT Adaptation to the environment plays an essential role in yeast evolution as a consequence of selective pressures. Lachancea thermotolerans, a yeast related to fermentation and one of the current trends in wine technology research, has undergone an anthropisation process, leading to a notable genomic and phenomic differentiation.
Javier Vicente, Anne Friedrich, Joseph Schacherer, Kelle Freel, Domingo Marquina, Antonio Santos   +5 more
wiley   +1 more source

Oxygen Consumption and Anaerobic Glycolysis of the Muscle from the Patients with Progressive Muscular Dystrophy

, 1963
Keiya Tada, Haruko Hirono, Hisashi Miyazawa   +2 more
openalex   +2 more sources