Results 251 to 260 of about 70,398 (322)

Harnessing Gut Microbiome–Brain–Liver Crosstalk: Novel Therapeutic Strategies for Metabolic Dysfunction‐Associated Steatotic Liver Disease

Medicine Bulletin, Volume 1, Issue 2, Page 136-153, December 2025.
This review reveals the complex mechanisms by which the brain–gut–liver axis (particularly the gut microbiota and its metabolites) drives MASLD, highlighting the therapeutic value of using phages to target and eliminate pathogenic bacteria and their metabolic products.
Xingtao Zhao, Ruolan Li, Jingdong Zhao, Ruiqi Sun, Shuo Zhang, Qiong Pan, Hongyan Lu, Jin Chai   +7 more
wiley   +1 more source

Glioma neuron symbiosis: a hypothesis. [PDF]

Front Neurosci
Schurr A.
europepmc   +1 more source

Anaerobic Glycolysis and Glycogenolysis do not Release Protons and do not Cause Acidosis

, 2019
Rossana Pesi, Francesco Balestri, Piero Luigi Ipata   +2 more
openalex   +1 more source

Sulfated Polysaccharides From Gracilaria gracilis (Red Seaweed) Restores Testicular Glucose Metabolism by Improving FSH and Insulin Signaling in Rats With Type 2 Diabetes

Molecular Nutrition &Food Research, Volume 69, Issue 23, December 2025.
Sulfated polysaccharides from red seaweed improved testicular FSH and insulin signaling, which upregulated GLUT4 level and improved glycolysis and energy metabolism in testes of diabetic rats. ABSTRACT Testicular glucose homeostasis plays important roles in testicular energy metabolism and male fertility, but it is altered in type 2 diabetes (T2D ...
Ochuko L. Erukainure, Tosin A. Olasehinde, Olanrewaju S. Olayeriju, Bukola Omotoso, Md. Shahidul Islam, Ademola O. Olaniran   +5 more
wiley   +1 more source

Androgen-Induced Lactic Acid Accumulation Contributes to the Apoptosis of Ovarian Granulosa Cells in Polycystic Ovary Syndrome Mice. [PDF]

Antioxidants (Basel)
Zhao B, Fan L, Liu M, Wu H, Zhang Y, Shen Q, Kang J.   +6 more
europepmc   +1 more source

Nuclear spin hyperpolarization of pyruvate enables longitudinal monitoring of treatment response in intestinal tumor organoids

Magnetic Resonance in Medicine, Volume 94, Issue 6, Page 2567-2577, December 2025.
Abstract Purpose Colorectal cancer, a leading cause of death in the Western world, is increasingly affecting younger populations. The Warburg effect, characterized by enhanced lactate production, is a hallmark of this cancer type. Although 18F‐FDG PET‐CT is commonly used for diagnosis, MRI offers higher spatial and chemical resolution without the ...
Josh P. Peters, Hang Xiang, Charbel D. Assaf, Farhad Haj Mohamad, Philip Rosenstiel, Stefan Schreiber, Jan‐Bernd Hövener, Konrad Aden, Andrey N. Pravdivtsev   +8 more
wiley   +1 more source

Lactate in Heart Failure. [PDF]

Int J Mol Sci
Gajewski P, Wilk MM, Aleksandrowicz K, Ponikowska B, Zymliński R.   +4 more
europepmc   +1 more source

Lactate‐mediated activation of GPR81 regulates BCR/Abl protein expression in chronic myeloid leukemia cells selected under low oxygen tension

The Journal of Pathology, Volume 267, Issue 4, Page 399-409, December 2025.
Abstract Chronic myeloid leukemia (CML) is a stem cell‐driven neoplasia characterized by the expression of the constitutively active tyrosine kinase (TK) BCR/Abl. Under low oxygen, a condition that characterizes stem cell niches (SCNs) in vivo, the oncogenic BCR/Ablprotein is suppressed.
Giulio Menegazzi, Dayana Desideri, Alessio Biagioni, Elisabetta Rovida, Persio Dello Sbarba, Silvia Peppicelli   +5 more
wiley   +1 more source

Metagenomic Insights Into the Ecology, Taxonomy and Metabolic Capabilities of ‘Candidatus Darwinibacteriales’ Ord. Nov. (Formerly MBA03), a Potential Key Player in Anaerobic Digestion

Microbial Biotechnology, Volume 18, Issue 12, December 2025.
Metagenomic analysis of anaerobic digesters revealed a dominant, uncultured bacterial taxon—MBA03—now proposed as ‘Candidatus Darwinibacteriales’ ord. nov. This newly defined order includes potential syntrophic acetate‐oxidising bacteria (SAOB), suggesting a key role in methane production.
Roser Puchol‐Royo, Javier Pascual, Asier Ortega‐Legarreta, Pascal Otto, Jeroen Tideman, Sjoerd‐Jan de Vries, Christian Abendroth, Kristie Tanner, Manuel Porcar, Adriel Latorre‐Perez   +9 more
wiley   +1 more source

Metabolic remodeling and cardiac dysfunction in left ventricular noncompaction: Insights from the MYH7 Q315R model. [PDF]

PLoS One
Takarada S, Hata Y, Yaku K, Izumi H, Fujii K, Omura M, Takasaki I, Tsuboi K, Okabe M, Miyao N, Nakaoka H, Ibuki K, Ozawa S, Nakagawa T, Hasegawa H, Ichimata S, Nishida N, Mori H, Yanagibashi Y, Takao K, Ichida F, Hirono K.   +21 more
europepmc   +1 more source