Results 251 to 260 of about 345,476 (333)

Identification of Functional Cellular Markers Related to Human Health, Frailty and Chronological Age

open access: yesAging Cell, Volume 24, Issue 9, September 2025.
Human skin fibroblasts in vitro preserve the memory of age and health. ABSTRACT Aging leads to a decline in physiological reserves, an increase in age‐related diseases, reduced functional ability and a shortened healthspan. While molecular markers of chronological aging exist, their link to general health and intrinsic capacity (IC), a composite ...
Chloé Brodeau   +21 more
wiley   +1 more source

Dual Role of Natural Killer Cells in Early Pregnancy: Immunopathological Implications and Therapeutic Potential in Recurrent Spontaneous Abortion and Recurrent Implantation Failure

open access: yesCell Proliferation, Volume 58, Issue 9, September 2025.
This article elaborates on the role of NK cells in early pregnancy from multiple perspectives, including molecular mechanisms and therapeutic interventions. It also discusses how NK cell dysfunction contributes to RSA and RIF, aiming to provide insights for future research on NK cell mechanisms and clinical treatment of RSA and RIF.
Defeng Guan   +5 more
wiley   +1 more source

Compositional and Metabolomic Shifts of the Gut Microbiome in Alcohol‐Related Liver Disease

open access: yesJournal of Gastroenterology and Hepatology, Volume 40, Issue 9, Page 2176-2189, September 2025.
ABSTRACT Alcohol‐related liver disease (ALD) is a major global health concern characterized by steatosis and liver inflammation due to chronic alcohol consumption. Emerging evidence suggests that ALD is not solely a liver pathology but also involves dysfunction of the gut‐liver axis, where alterations in the gut microbiota play a significant role ...
Cheng‐Hao Kuo   +4 more
wiley   +1 more source

Single‐Cell Sequencing: A Sharp Sword for Deciphering Biological Innovations and Evolutionary Adaptations in Lower Vertebrates and Invertebrates

open access: yesReviews in Aquaculture, Volume 17, Issue 4, September 2025.
Single‐cell sequencing sheds light on cellular diversity, development, and immune evolution in fish and invertebrates, offering new insights into environmental adaptation and evolutionary biology. ABSTRACT Single‐cell sequencing (SCS) technology has revolutionized the study of cellular heterogeneity by enabling the exploration of biological processes ...
Chongbin Hu   +5 more
wiley   +1 more source

Combined effects of mechanical overload and high‐intensity interval training on skeletal muscle hypertrophy in male mice

open access: yesPhysiological Reports, Volume 13, Issue 17, September 2025.
Abstract Athletes often perform concurrent training that combines different exercise modalities. It is believed that muscle hypertrophic adaptation is inhibited by endurance exercise; however, the molecular mechanisms underlying the effects of high‐intensity, short‐duration exercise on muscle hypertrophic responses remain unclear.
Hayato Shinkai   +7 more
wiley   +1 more source

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