Results 31 to 40 of about 341,458 (322)

ANAEROBIC GLYCOLYSIS OF THE BRAIN IN EXPERIMENTAL POLIOMYELITIS [PDF]

Journal of Experimental Medicine, 1945
The rate of anaerobic glycolysis of brain tissue was compared for normal animals and animals with experimentally induced poliomyelitis, using two different strains of mice and two different procedures. The report of interference of poliomyelitis with anaerobic glycolysis of brain was not confirmed.
John M. Reiner, Irving I. Rusoff, Harland G. Wood   +2 more
openaire   +3 more sources

Synaptic modifications transform neural networks to function without oxygen

BMC Biology, 2023
Background Neural circuit function is highly sensitive to energetic limitations. Much like mammals, brain activity in American bullfrogs quickly fails in hypoxia.
Lara Amaral-Silva, Joseph M. Santin
doaj   +1 more source

Adenosine Triphosphate and Carbon Efficient Route to Second Generation Biofuel Isopentanol. [PDF]

, 2020
Climate change necessitates the development of CO2 neutral or negative routes to chemicals currently produced from fossil carbon. In this paper we demonstrate a pathway from the renewable resource glucose to next generation biofuel isopentanol by pairing
Chiniquy, Jennifer, Eiben, Christopher B, Goyal, Garima, Hillson, Nathan J, Kaplan, Nurgul, Keasling, Jay D, Lee, Taek Soon, Mendez-Perez, Daniel, Thompson, Mitchell G, Tian, Tian   +9 more
core   +1 more source

Notch signaling regulates metabolic heterogeneity in glioblastoma stem cells. [PDF]

, 2017
Glioblastoma (GBM) stem cells (GSCs) reside in both hypoxic and vascular microenvironments within tumors. The molecular mechanisms that allow GSCs to occupy such contrasting niches are not understood.
Barcellos-Hoff, Mary Helen, Bayin, N Sumru, Chesler, Mitch, Chiriboga, Luis, Dolgalev, Igor, Doyle, Werner, Frenster, Joshua D, Galifianakis, Nataliya, Golfinos, John G, Heguy, Adriana, Illa-Bochaca, Irineu, Khahera, Anadjeet, Modrek, Aram S, Ortenzi, Valerio, Placantonakis, Dimitris G, Sen, Rajeev, Serrano, Jonathan, Si, Sheng, Snuderl, Matija, Tsirigos, Aristotelis, Zagzag, David   +20 more
core   +5 more sources

Synthesis and application of (18F) fluorodeoxyglucose in oncology diagnosis

Journal of Education, Health and Sport, 2017
[18F] Fluorodeoxyglucose ([18F] FDG) is the most commonly used radiopharmaceutical in clinical positron emission tomography (PET) in oncology. Cancer cells create their own specific microenvironment to survive and grow.
Mateusz Wędrowski, Paweł Waśniowski, Ewelina Wędrowska, Elżbieta Piskorska, Jolanta Czuczejko, Bogdan Małkowski, Walery Żukow   +6 more
doaj   +3 more sources

Heterogeneity and proliferation of invasive cancer subclones in game theory models of the Warburg effect [PDF]

, 2015
OBJECTIVES: The Warburg effect, the switch from aerobic energy production to anaerobic glycolysis, promotes tumour proliferation and motility by inducing acidification of the tumour microenvironment.
Archetti, Archetti, Archetti, Archetti, Archetti, Archetti, Bach, Basanta, Basanta, Basanta, Bergers, Bhujwalla, Buchler, Casciari, Feron, Gambhir, Gatenby, Gatenby, Gatenby, Gatenby, Gillies, Griffiths, Hanahan, He, Ibrahim Hashim, Ibrahim Hashim, Kelloff, Kianercy, Kunkel, Lardner, Martin, Martin, Maynard Smith, Mochiki, Park, Patel, Pauwels, Perc, Postovit, Postovit, Rajendran, Robey, Rohzin, Rubin, Schornack, Semenza, Shi, Silva, Smallbone, Smallbone, Sonveaux, Tomlinson, Tomlinson, Warburg, Williams, Wojtkowiak   +55 more
core   +1 more source

Sugarcane mosaic virus orchestrates the lactate fermentation pathway to support its successful infection

Frontiers in Plant Science, 2023
Viruses often establish their own infection by altering host metabolism. How viruses co-opt plant metabolism to support their successful infection remains an open question.
Tong Jiang, Tong Jiang, Kaitong Du, Pei Wang, Xinhai Wang, Lianyi Zang, Dezhi Peng, Xi Chen, Geng Sun, Hao Zhang, Zaifeng Fan, Zhiyan Cao, Tao Zhou   +12 more
doaj   +1 more source

Explicit consideration of topological and parameter uncertainty gives new insights into a well-established model of glycolysis [PDF]

, 2013
Previous models of glycolysis in the sleeping sickness parasite Trypanosoma brucei assumed that the core part of glycolysis in this unicellular parasite is tightly compartimentalized within an organelle, the glycosome, which had previously been shown to ...
Achcar, Albert, Bakker, Bakker, Bakker, Bakker, Blattner, Chevalier, Clarkson, Clarkson, Cronín, Fairlamb, Fairlamb, Gualdron-López, Gualdrón-López, Guerra-Giraldez, Haanstra, Haanstra, Hammond, Helfert, Häusler, Michels, Miškovíc, Murabito, Opperdoes, Rizk, Satish Kumar, Steiger, Tran, Visser, Wang   +30 more
core   +1 more source

The silicon trypanosome [PDF]

, 2010
African trypanosomes have emerged as promising unicellular model organisms for the next generation of systems biology. They offer unique advantages, due to their relative simplicity, the availability of all standard genomics techniques and a long history
BARBARA M. BAKKER, CHRISTINE CLAYTON, Duffieux, HANS V. WESTERHOFF, Hornberg, KEITH MATTHEWS, MARK GIROLAMI, MICHAEL P. BARRETT, PAUL A. M. MICHELS, R. LUISE KRAUTH-SIEGEL, RAINER BREITLING   +10 more
core   +13 more sources

Integration between Glycolysis and Glutamate-Glutamine Cycle Flux May Explain Preferential Glycolytic Increase during Brain Activation, Requiring Glutamate

Frontiers in Integrative Neuroscience, 2017
The 1988 observation by Fox et al. (1988) that brief intense brain activation increases glycolysis (pyruvate formation from glucose) much more than oxidative metabolism has been abundantly confirmed.
Leif Hertz, Ye Chen
doaj   +1 more source