Results 41 to 50 of about 70,398 (322)

Minimizing acetate formation in E. coli fermentations [PDF]

, 2007
Escherichia coli remains the best established production organisms in industrial biotechnology. However, during aerobic fermentation runs at high growth rates, considerable amounts of acetate are accumulated as by-product.
De Maeseneire, Sofie, De Mey, Marjan, Soetaert, Wim, Vandamme, Erick   +3 more
core   +2 more sources

hZIP1 Inhibits Progression of Clear Cell Renal Cell Carcinoma by Suppressing NF-kB/HIF-1α Pathway

Frontiers in Oncology, 2021
PurposeAccumulating literature has suggested that hZIP1 and HIF-1α play vital roles in the tumor process of clear cell renal cell carcinoma (ccRCC). However, the functional roles of hZIP1 and HIF-1α in ccRCC remain largely unknown.MethodsHIF-1α protein ...
Bo Zhan, Xiao Dong, Yulin Yuan, Zheng Gong, Bohan Li   +4 more
doaj   +1 more source

NAD(P)H fluorescence lifetime imaging of live intestinal nematodes reveals metabolic crosstalk between parasite and host

Scientific Reports, 2022
Infections with intestinal nematodes have an equivocal impact: they represent a burden for human health and animal husbandry, but, at the same time, may ameliorate auto-immune diseases due to the immunomodulatory effect of the parasites.
Wjatscheslaw Liublin, Sebastian Rausch, Ruth Leben, Randall L. Lindquist, Alexander Fiedler, Juliane Liebeskind, Ingeborg E. Beckers, Anja E. Hauser, Susanne Hartmann, Raluca A. Niesner   +9 more
doaj   +1 more source

Glycolytic reprograming in Salmonella counters NOX2-mediated dissipation of ΔpH. [PDF]

, 2020
The microbial adaptations to the respiratory burst remain poorly understood, and establishing how the NADPH oxidase (NOX2) kills microbes has proven elusive. Here we demonstrate that NOX2 collapses the ΔpH of intracellular Salmonella Typhimurium.
Chakraborty, Sangeeta, Desai, Prerak, Fitzsimmons, Liam, Kim, Ju-Sim, Liu, Lin, McClelland, Michael, Porwollik, Steffen, Vazquez-Torres, Andres   +7 more
core  

Heterogeneity and proliferation of invasive cancer subclones in game theory models of the Warburg effect [PDF]

, 2015
OBJECTIVES: The Warburg effect, the switch from aerobic energy production to anaerobic glycolysis, promotes tumour proliferation and motility by inducing acidification of the tumour microenvironment.
Archetti, Archetti, Archetti, Archetti, Archetti, Archetti, Bach, Basanta, Basanta, Basanta, Bergers, Bhujwalla, Buchler, Casciari, Feron, Gambhir, Gatenby, Gatenby, Gatenby, Gatenby, Gillies, Griffiths, Hanahan, He, Ibrahim Hashim, Ibrahim Hashim, Kelloff, Kianercy, Kunkel, Lardner, Martin, Martin, Maynard Smith, Mochiki, Park, Patel, Pauwels, Perc, Postovit, Postovit, Rajendran, Robey, Rohzin, Rubin, Schornack, Semenza, Shi, Silva, Smallbone, Smallbone, Sonveaux, Tomlinson, Tomlinson, Warburg, Williams, Wojtkowiak   +55 more
core   +1 more source

Genome-wide association study reveals that enolase gene OsEE1 regulates coleoptile elongation in rice under anaerobic conditions

Crop Journal
Submergence can induce anaerobic stress on germinating seedlings in direct seeded rice paddy fields, limiting the practice of direct seeding. Longer coleoptiles improves the anaerobic tolerance of rice seedlings under submerged conditions.
Dandan Li, Kai Liu, Ling Su, Jinrui Li, Yuanyuan Guo, Tao Guo, Hong Liu, Dehua Rao   +7 more
doaj   +1 more source

INDUCTION OF ANAEROBIC PROCESSES IN BAIKAL ENDEMICS EULIMNOGAMMARUS VITTATUS (DYB.) AND E. VERRUCOSUS (DYB.) (AMPHIPODA, CRUSTACEA) [PDF]

Journal of Stress Physiology & Biochemistry, 2006
The data confirming the ability of Baikalian endemic species Eulimnogammarus vittatus (Dyb.) and E. verrucosus (Dyb.) to activate anaerobic glycolysis under hypoxia are presented. The differences in the degree and the rate of lactic acid accumulation and
Timofeyev M.A., Kirichenko K.A., Rokhin A.V., Bedulina D.S., Chernyshova K.P., Pobezhimova T.P.   +5 more
doaj  

ATP and Lactate Quantification

Bio-Protocol, 2013
Cells use glucose to generate energy by two different metabolic processes: lactic fermentation and aerobic respiration. In the first common series of reactions, glucose is converted into pyruvate.
Isaline Rowe, Marco Chiaravalli, Alessandra Boletta   +2 more
doaj   +1 more source

Explicit consideration of topological and parameter uncertainty gives new insights into a well-established model of glycolysis [PDF]

, 2013
Previous models of glycolysis in the sleeping sickness parasite Trypanosoma brucei assumed that the core part of glycolysis in this unicellular parasite is tightly compartimentalized within an organelle, the glycosome, which had previously been shown to ...
Achcar, Albert, Bakker, Bakker, Bakker, Bakker, Blattner, Chevalier, Clarkson, Clarkson, Cronín, Fairlamb, Fairlamb, Gualdron-López, Gualdrón-López, Guerra-Giraldez, Haanstra, Haanstra, Hammond, Helfert, Häusler, Michels, Miškovíc, Murabito, Opperdoes, Rizk, Satish Kumar, Steiger, Tran, Visser, Wang   +30 more
core   +1 more source

Molecular crowding defines a common origin for the Warburg effect in proliferating cells and the lactate threshold in muscle physiology [PDF]

, 2011
Aerobic glycolysis is a seemingly wasteful mode of ATP production that is seen both in rapidly proliferating mammalian cells and highly active contracting muscles, but whether there is a common origin for its presence in these widely different systems is
A Vazquez, A Vazquez, A Vazquez, Alexei Vazquez, AV Hill, B Lee, D Voet, DA Hume, DG Hardie, DJ Marcinek, DR Wise, E Blomstrand, G Parra-Bonilla, H Hoppeler, J Achten, J Schellenberger, JM Savinell, JW Locasale, K Schwerzmann, K Sheikh, KE Conley, KR Short, MC Hogan, MG Vander Heiden, MJ Joyner, O Trabold, O Warburg, P Gao, PA Farrell, PR Rich, QK Beg, R Wibom, R Williams, RJ DeBerardinis, RK Scopes, T Shlomi, T Wang, U Glas, W Hu, WF Kemper, WH Munyon, XY Hou, Y Liu, Y Liu, Y Sidorenko, Yamir Moreno, Zoltán N. Oltvai   +46 more
core   +6 more sources