Results 41 to 50 of about 341,458 (322)
Cells, 2022 Fanconi Anaemia (FA) is a rare recessive genetic disorder characterized by a defective DNA repair mechanism. Although aplastic anaemia is the principal clinical sign in FA, patients develop a head and neck squamous cell carcinoma (HNSCC) with a frequency
Nadia Bertola +3 more
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Early pH Changes in Musculoskeletal Tissues upon Injury-Aerobic Catabolic Pathway Activity Linked to Inter-Individual Differences in Local pH [PDF]
, 2020 Local pH is stated to acidify after bone fracture. However, the time course and degree of acidification remain unknown. Whether the acidification pattern within a fracture hematoma is applicable to adjacent muscle hematoma or is exclusive to this ...
Berkmann, Julia C. +8 more
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Respiration and Anaerobic Glycolysis of Transplanted Cartilage
Plastic and Reconstructive Surgery, 1952 Summary1. The rate of respiration and anaerobic glycolysis of fresh rabbit costal cartilage is among the lowest of all tissues. Carbohydrate metabolism is predominantly anaerobic. 2. Transplantation resulted in approximately a 45% decline in the rates of both respiration and anaerobic glycolysis in both the autografts and homografts during the first 7 ...
James A. Bain +2 more
openaire +4 more sources
The paradox between resistance to hypoxia and liability to hypoxic damage in hyperglycemic peripheral nerves. Evidence for glycolysis involvement [PDF]
, 1993 Isolated ventral and dorsal rat spinal roots incubated in normal (2.5 mM) or high glucose (25 mM) concentrations or in high concentrations of other hexoses were exposed transiently to hypoxia (30 min) in a solution of low buffering power.
Grafe, Peter +2 more
core +1 more source
Regulatory Mechanisms in Biosystems, 2023 Currently, the use of nanotechnology opens up new opportunities to influence the processes of anaerobic glycolysis and the activity of hexose monophosphate reactions in preserved erythrocytes.
A. N. Belousov +5 more
doaj +1 more source
Cardiosphere-derived cells demonstrate metabolic flexibility that Is influenced by adhesion status [PDF]
, 2017 Adult stem cells demonstrate metabolic flexibility that is regulated by cell adhesion status. The authors demonstrate that adherent cells primarily utilize glycolysis, whereas suspended cells rely on oxidative phosphorylation for their ATP needs.
Abraham, M. Roselle +13 more
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hZIP1 Inhibits Progression of Clear Cell Renal Cell Carcinoma by Suppressing NF-kB/HIF-1α Pathway
Frontiers in Oncology, 2021 PurposeAccumulating literature has suggested that hZIP1 and HIF-1α play vital roles in the tumor process of clear cell renal cell carcinoma (ccRCC). However, the functional roles of hZIP1 and HIF-1α in ccRCC remain largely unknown.MethodsHIF-1α protein ...
Bo Zhan +4 more
doaj +1 more source
Mass conserved elementary kinetics is sufficient for the existence of a non-equilibrium steady state concentration [PDF]
, 2012 Living systems are forced away from thermodynamic equilibrium by exchange of mass and energy with their environment. In order to model a biochemical reaction network in a non-equilibrium state one requires a mathematical formulation to mimic this forcing.
Fleming, Ronan M. T., Thiele, Ines
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Mediators of Inflammation, 2014 To investigate the role of AEG-1 in glycolysis and tumorigenesis, we construct myc-AEG-1 expression vector and demonstrate a novel mechanism that AEG-1 may increase the activity of AMPK by Thr172 phosphorylation.
Hong-tao Song +5 more
doaj +1 more source
ACS Nano, 2017 In this study, we developed a general method to decorate plasmonic gold nanorods (GNRs) with a CD44-targeting functional polymer, containing a hyaluronic acid (HA)-targeting moiety and a small molecule Glut1 inhibitor of diclofenac (DC), to obtain GNR/HA-
Wei‐Hai Chen +7 more
semanticscholar +1 more source