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Bacterial membrane vesicles restore gut anaerobiosis [PDF]
npj Biofilms and MicrobiomesInflammation damages the epithelial cell barrier, allowing oxygen to leak into the lumen of the gut. Respiring E. coli and other Enterobacteriaceae produce proinflammatory lipopolysaccharide, exacerbating inflammatory bowel disease.
Norman Pitt +6 more
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Impact of Anaerobiosis on Expression of the Iron-Responsive Fur and RyhB Regulons
MBio, 2015 Iron, a major protein cofactor, is essential for most organisms. Despite the well-known effects of O2 on the oxidation state and solubility of iron, the impact of O2 on cellular iron homeostasis is not well understood.
Kevin S Myers, Dongjun Chung, Dan M Park
exaly +3 more sources
Anaerobiosis and Mutations Can Reduce Susceptibility of Pseudomonas aeruginosa to Tobramycin Without Reducing the Cellular Concentration of the Antibiotic [PDF]
PathogensChronic infections of Pseudomonas aeruginosa are commonly treated with tobramycin. During infections, the bacteria can exist under conditions of oxygen deprivation that render them less susceptible to this antibiotic.
Woravimol Krittaphol +3 more
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The yhiM gene codes for an inner membrane protein involved in GABA export in Escherichia coli [PDF]
AIMS Microbiology, 2017 In order to survive the exposure to acid pH, Escherichia coli activates molecular circuits leading from acid tolerance to extreme acid resistance (AR). The activation of the different circuits involves several global and specific regulators affecting the
Angela Tramonti +3 more
doaj +4 more sources
Nature Communications, 2018 Osm1 and Frd1 are soluble fumarate reductases from yeast that are critical for allowing survival under anaerobic conditions. Although they maintain redox balance during anaerobiosis, the underlying mechanism is not understood. Here, we report the crystal
Young-Jin Son, Younho Lee, Hara Kang
exaly +2 more sources
Scientific Reports, 2019 The airways of individuals with cystic fibrosis (CF) are abundantly colonised by Staphylococcus aureus and Pseudomonas aeruginosa. Co-infecting hypoxic regions of static mucus within CF airways, together with decreases in pulmonary function, mucus ...
Laura Jane Leslie +2 more
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Anaerobiosis of fluid mud [PDF]
Nature, 1976 OBSERVATIONS in estuaries have reported the existence of ephemeral deposits of semi-fluid mud1,2 extending several metres from the bottom. These muds differ from ‘mud’ as normally understood in that although they form definite boundaries with the overlaying water mass they have a lower solid content and settle, if at all, only very slowly.
A. Sylvester, G. C. WARE
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Global tRNA misacylation induced by anaerobiosis and antibiotic exposure broadly increases stress resistance inEscherichia coli [PDF]
Nucleic Acids Research, 2016 High translational fidelity is commonly considered a requirement for optimal cellular health and protein function. However, recent findings have shown that inducible mistranslation specifically with methionine engendered at the tRNA charging level occurs
Michael Schwartz +3 more
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Proteomic Delineation of the ArcA Regulon in Salmonella Typhimurium During Anaerobiosis
Molecular and Cellular Proteomics, 2018 Salmonella enterica serovar Typhimurium (S. Typhimurium) is one of the most used models for bacterial pathogenesis and successful infection requires its adaptation to the low oxygen environment in host gastrointestinal tracts.
Jiaqi, Cheng Chang, Aixin Yan
exaly +2 more sources
Frontiers in Microbiology, 2018 Current notion presumes that only one protein is encoded at a given bacterial genetic locus. However, transcription and translation of an overlapping open reading frame (ORF) of 186 bp length were discovered by RNAseq and RIBOseq experiments. This ORF is
Sarah M. Hücker +6 more
doaj +2 more sources