Results 121 to 130 of about 35,970 (259)

A case of corticosteroid-dependent recurrent pericarditis with different response to two IL-1 blocking agents [PDF]

, 2015
Background: Recurrent pericarditis (RP) represents the most troublesome presentation of pericarditis and has a controversial pathogenesis that crosses infectious, auto-immune and auto-inflammatory pathways.
A von Scheven-Gête, F Angelini, K Theodoropoulou, M Hofer, M Prsa, S Bressieux-Degueldre, T Boulos   +6 more
core   +2 more sources

Predictors of Mortality in Severe and Critical COVID-19 Patients Receiving High Dose Intravenous Anakinra

, 2023
Murat Bektaş, Muhammed İkbal Kılıç
openalex   +2 more sources

T‐Cell–Redirecting Immunotherapies in Relapsed/Refractory Mantle Cell Lymphoma: Current Evidence, Sequencing, and Future Directions

European Journal of Haematology, EarlyView.
ABSTRACT Relapsed/refractory (R/R) mantle cell lymphoma (MCL) remains a therapeutic challenge, particularly in patients with high‐risk features or prior exposure to Bruton's tyrosine kinase inhibitors (BTKis). The advent of T‐cell–redirecting immunotherapies, including chimeric antigen receptor T‐cell (CAR‐T) therapy and bispecific antibodies (BsAbs ...
Santino Caserta, Enrica Antonia Martino, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Peripheral blood mononuclear cell secretome from patients with autoimmune encephalitis promotes seizures in vitro

Epilepsia, EarlyView.
Abstract Objective Autoimmune encephalitis (AE) is characterized by inflammatory processes in the central nervous system and frequently presents with seizures. Even though an ictogenic potential has been shown for some antibodies against neuronal surface antigens (NSAbs), AE pathophysiology is complex, and NSAbs‐independent mechanisms are likely to ...
Sara Prevosti, Alessio Passalacqua, Maria Cristina Regondi, Giada D'Ambrosio, Alessandra Morano, Michele Romoli, Giulia Maira, Flavio Villani, Pietro Mattioli, Diego Franciotta, Andrea Stabile, Marco de Curtis, Matteo Gastaldi, Francesco Deleo, Laura Librizzi   +14 more
wiley   +1 more source

The use of anakinra in a patient with gout and long-term follow-up of rheumatoid arthritis

, 2023
Е. В. Черемушкина, М. С. Елисеев, A. S. Semashko, А. В. Алексеева, А. М. Лила   +4 more
openalex   +2 more sources

An extreme type of new onset refractory status epilepticus with stimulus‐induced seizures in pharmacological isoelectric states

Epilepsia, EarlyView.
Abstract Objective Status epilepticus (SE) is a common neurological emergency associated with high morbidity and mortality. SE is classified as refractory when it persists despite benzodiazepine and second‐line antiseizure medication. Managing refractory SE in the intensive care setting often requires high doses of sedative drugs, which can induce ...
Julie Lévi‐Strauss, Vi‐Huong Nguyen‐Michel, Espártaco Moraes Ribeiro, Virginie Lambrecq, Aurélie Hanin, Sophie Demeret, Vincent Navarro   +6 more
wiley   +1 more source

Hyper-IgD and Periodic Fever Syndrome: a New MVK Mutation (p.R277G) Associated with a Severe Phenotype [PDF]

, 2014
Hyperimmunoglobulinemia D and periodic fever syndrome (HIDS; MIM#260920) is a rare recessively-inherited autoinflammatory condition caused bymutations in the MVK gene, which encodes for mevalonate kinase, an essential enzyme in the isoprenoid pathway ...
Aróstegui, J, Brito, MJ, Conde, M, Neves, C, Santos, J   +4 more
core   +1 more source

A randomised placebo controlled trial of anakinra for treating pustular psoriasis: statistical analysis plan for stage two of the APRICOT trial [PDF]

, 2020
Suzie Cro, Prakash A. Patel, Juliet N. Barker, David Burden, C.E.M. Griffiths, Helen J. Lachmann, Nick J. Reynolds, Richard B. Warren, Francesca Capon, Catherine Smith, Victoria Cornelius   +10 more
openalex   +1 more source

Standard complete blood count to predict long‐term outcomes in febrile infection–related epilepsy syndrome (FIRES): A multicenter study

Epilepsia, EarlyView.
Abstract Objective We investigated whether complete blood count (CBC) analyses during intensive care unit stay could predict 12‐month outcomes in patients with cryptogenic febrile infection–related epilepsy syndrome (FIRES), a subset of new‐onset refractory status epilepticus (NORSE).
Martin Guillemaud, Aurélie Hanin, James J. Riviello, Mario Chavez, Ayush Batra, Megan Berry, Francesca Bisulli, Carlos Castillo‐Pinto, Carla Cobos‐Hernandez, Sophie Demeret, Krista Eschbach, Raquel Farias‐Moeller, Madeline Fields, Nicolas Gaspard, Elizabeth E. Gerard, Teneille E. Gofton, Margaret T. Gopaul, Matthew D. Gruen, Anthony D. Jimenez, Karnig Kazazian, Minjee Kim, Marwa Mansour, Lara Marcuse, Clémence Marois, Mikaela Morales, Lorenzo Muccioli, Elena Pasini, Michelle M. Pham, Santiago Philibert Rosas, Aaron F. Struck, Nathan Torcida, Mark S. Wainwright, Ji Yeoun Yoo, Eyal Muscal, Vincent Navarro, Lawrence J. Hirsch, Yichen Lai   +36 more
wiley   +1 more source

Impact of an Interleukin-1 Receptor Antagonist and Erythropoietin on Experimental Myocardial Ischemia/Reperfusion Injury

The Scientific World Journal, 2012
Background. Revascularization of infarcted myocardium results in release of inflammatory cytokines mediating myocardial reperfusion injury and heart failure. Blockage of inflammatory pathways dampens myocardial injury and reduces infarct size.
Christina Grothusen, Angelika Hagemann, Tim Attmann, Jan Braesen, Ole Broch, Jochen Cremer, Jan Schoettler   +6 more
doaj   +1 more source