Results 91 to 100 of about 414,941 (338)

COLOR III: a multicentre randomised clinical trial comparing transanal TME versus laparoscopic TME for mid and low rectal cancer [PDF]

, 2015
Total mesorectal excision (TME) is an essential component of surgical management of rectal cancer. Both open and laparoscopic TME have been proven to be oncologically safe.
Bonjer, HJ, De Lange-de Klerk, ES, Deijen, CL, Hanna, GB, Lacy, AM, Mavroveli, S, Sietses, C, Tsai, A, Tuynman, JB, Velthuis, S   +9 more
core   +1 more source

Impact of Two‐Team Surgery on Short‐ and Long‐Term Outcomes of Transanal Total Mesorectal Excision for Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
This study investigated the impact of two‐team surgery on short‐ and long‐term outcomes of transanal total mesorectal excision for rectal cancer. Two‐team surgery has some advantages over one‐team surgery, such as shorter operation time, decreased estimated blood loss, increased number of lymph nodes dissected, and decreased positive distal margin ...
Nobuaki Hoshino, Koya Hida, Yukinari Tokoro, Kazutaka Obama, Takeru Matsuda, Ichiro Takemasa, Tomonori Akagi, Masafumi Inomata, Shigenori Homma, Nobuki Ichikawa, Yoshihiro Kakeji, Seiichiro Yamamoto, Takeshi Naitoh, Ta‐Ta‐Mi study group collaboratives in Japan Society of Laparoscopic Colorectal Surgery   +13 more
wiley   +1 more source

Identification of HSP90B1 in pan-cancer hallmarks to aid development of a potential therapeutic target

Molecular Cancer
Heat shock proteins play crucial roles in various biochemical processes, encompassing protein folding and translocation. HSP90B1, a conserved member of the heat shock protein family, growing evidences have demonstrated that it might be closely associated
Xiaoliang Huang, Weiming Zhang, Na Yang, Yujie Zhang, Tianyu Qin, Hanyi Ruan, Yan Zhang, Chao Tian, Xianwei Mo, Weizhong Tang, Jungang Liu, Beibei Zhang   +11 more
doaj   +1 more source

Clearance of human papillomavirus related anal condylomas after oral and endorectal multistrain probiotic supplementation in an HIV positive male: A case report. [PDF]

, 2018
Go to: Introduction: Here we present the case of a 56-year-old human immunodeficiency virus (HIV)-infected man with multiple anal condylomas and positivity for human papilloma virus (HPV) 18 on anal brushing.
Bianchi, L, Cavallari, En, Ceccarelli, G, Ciardi, A, D'Ettorre, G, Pierangeli, A, Savinelli, S, Vullo, F   +7 more
core   +1 more source

Pelvic U-Net: multi-label semantic segmentation of pelvic organs at risk for radiation therapy anal cancer patients using a deeply supervised shuffle attention convolutional neural network [PDF]

, 2022
Michael Lempart, Martin Nilsson, Jonas Scherman, Christian Jamtheim Gustafsson, Mikael Nilsson, Sara Alkner, Jens Engleson, Gabriel Adrian, Per Munck af Rosenschöld, Lars Olsson   +9 more
openalex   +1 more source

Perioperative and Oncological Outcomes of Colorectal Cancer Surgery in Obese Patients: A Multicenter Retrospective Study

Annals of Gastroenterological Surgery, EarlyView.
The prognostic value of the log odds of positive lymph nodes (LODDS) across BMI categories was investigated in patients undergoing colorectal cancer resection. The exploratory evidence demonstrates that LODDS serves as a strong prognostic marker, and its adverse effect may be more pronounced in patients with higher BMI.
Kazuhiro Taguchi, Manabu Shimomura, Wataru Shimizu, Satoshi Ikeda, Masanori Yoshimitsu, Mohei Kouyama, Masahiro Nakahara, Hironori Kobayashi, Masatoshi Kochi, Yosuke Shimizu, Daisuke Sumitani, Shoichiro Mukai, Yuji Takakura, Yasuyo Ishizaki, Shinya Kodama, Masahiko Fujimori, Hiroshi Okuda, Takuya Yano, Tomoaki Bekki, Atsuhiro Watanabe, Saki Sato, Toshiyuki Moriuchi, Shohei Shiozaki, Kazuki Matsubara, Mizuki Yamaguchi, Tomohiro Adachi, Sho Ishikawa, Hideki Ohdan   +27 more
wiley   +1 more source

SREBP2 as a central player in cancer progression: potential for targeted therapeutics

Frontiers in Pharmacology
Recent studies have identified the reprogramming of lipid metabolism as a critical hallmark of malignancy. Enhanced cholesterol uptake and increased cholesterol biosynthesis significantly contribute to the rapid growth of tumors, with cholesterol also ...
Ruiqi Chen, Tianyu Chen, Xiang Li, Junfeng Yu, Min Lin, Siqi Wen, Man Zhang, Jinchi Chen, Bei Yi, Huage Zhong, Huage Zhong, Zhao Li   +11 more
doaj   +1 more source

The two-stage clonal expansion model in occupational cancer epidemiology: Results from three cohort studies [PDF]

, 2010
Copyright © 2010 by the BMJ Publishing Group Ltd. All rights reserved.Objectives: The objective of this work was to apply the two-stage clonal expansion model, with the intention to expand the literature on epidemiological applications of the model and ...
Gore, R, Kriebel, D, Zeka, A
core   +1 more source

Prognostic Impact of Histologic Subtypes in Mismatch Repair‐Deficient/Microsatellite Instability‐High Colorectal Cancer: A Single‐Center Retrospective Study of 1127 Stage 0–IV Patients

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Deficient mismatch repair/microsatellite instability‐High (dMMR/MSI‐H) colorectal cancer (CRC) generally confers a favorable survival yet is paradoxically enriched for poorly differentiated (Por) histology, which is linked to aggressive behavior.
Tomoyuki Momma, Hirokazu Okayama, Sohei Hayashishita, Hiroya Suzuki, Masanori Katagata, Takuro Matsumoto, Daisuke Ujiie, Shun Chida, Wataru Sakamoto, Koji Kono   +9 more
wiley   +1 more source

Impact of Abdominoperineal Resection on Postoperative Male Sexual Function After Minimally Invasive Rectal Cancer Surgery: A Subgroup Analysis From the LANDMARC Study

Annals of Gastroenterological Surgery, EarlyView.
Abdominoperineal resection (APR) after minimally invasive rectal cancer surgery was associated with significantly higher rates of erectile and early ejaculatory dysfunction compared with anal‐sparing surgery. Although ejaculatory function showed partial recovery over time, erectile dysfunction persisted up to 12 months postoperatively.
Taiki Kajiwara, Shinobu Ohnuma, Michiaki Unno, Masakatsu Numata, Tomohiro Yamaguchi, Koya Hida, Tomonori Akagi, Suguru Hasegawa, Akio Shiomi, Ryo Inada, Manabu Shiozawa, Keisuke Kazama, Masanori Hotchi, Masahiko Watanabe, Takeshi Naitoh   +14 more
wiley   +1 more source