Results 71 to 80 of about 88,414 (237)

Screening for Anal Cancer in HIV Positive Patients: Should We Make It A Standard-of-care?

Journal of Investigative Surgery, 2019
Anal cancer is biological similar to cervical cancer, and is preceded by anal intraepithelial neoplasia (AIN). Screening for AIN and treatments to reduce the risk of anal cancer are not established as guidelines of care for HIV-infected patients.
Jian Xu, Haiyang Zhou
doaj   +1 more source

Risk stratification and anal cancer screening in immunocompetent women with genital HPV: Value of multicentric HSIL and performance of HPV‐based screening

International Journal of Cancer, EarlyView.
What's New? Anal squamous cell carcinoma (ASCC) incidence is increasing, with most cases occurring in immunocompetent women. ASCC risk is linked in particular to genital human papillomavirus (HPV) infection and HPV‐associated high‐grade squamous intraepithelial lesions (HSILs).
Isabel Matas, Aureli Torné, Adela Saco, Cristina Martí, Ada Cardiel, Natalia Rakislova, Lorena Marimon, Ariel Glickman, Ingrid Victoria, Silvia Alós, Jesús Lopez‐Diaz, Pere Fusté, Jaume Ordi, Marta del Pino   +13 more
wiley   +1 more source

Factors associated with pathological complete remission after neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a real-world clinical setting

Frontiers in Oncology
ObjectiveThis study aims to identify factors associated with achieving a pathological complete remission (pCR) in patients with locally advanced rectal cancer (LARC) after neoadjuvant chemoradiotherapy (nCRT).MethodsWe conducted a cohort analysis of 171 ...
Minglin Lin, Minglin Lin, Junsheng Liu, Chongyuan Lan, Ming Qiu, Wei Huang, Wei Huang, Cun Liao, Cun Liao, Sen Zhang, Sen Zhang   +10 more
doaj   +1 more source

HPV infection, anal intra-epithelial neoplasia (AIN) and anal cancer: current issues

BMC Cancer, 2012
Background Human papillomavirus (HPV) is well known as the major etiological agent for ano-genital cancer. In contrast to cervical cancer, anal cancer is uncommon, but is increasing steadily in the community over the last few decades.
Stanley Margaret A, Winder David M, Sterling Jane C, Goon Peter KC   +3 more
doaj   +1 more source

Availability of Cancer Screening Across HIV Treatment Sites in the IeDEA Consortium

International Journal of Cancer, EarlyView.
In recent years, incorporating comprehensive cancer screening strategies into routine HIV care has gained growing attention. This survey of 220 sites providing HIV care across 41 countries shows that cervical cancer screening has increased in availability over time.
Rachael A. Pellegrino, Bryan E. Shepherd, Sanjay Pujari, Valeria Fink, Gad Murenzi, Miriam Nakalembe, Sally B. Coburn, Eliane Rohner, Antoine Jaquet, Caroline Lade, Brenda Crabtree Ramirez, Kathryn Anastos, Aggrey Semeere, Lesley S. Park, Limpho Mokone, Simon Boni, I Ketut Agus Somia, Emilia M. Jalil, Adebola Adedimeji, Omenge Orang'o, Michael J. Silverberg, Kumbirai Pise Quarter, Eugène Messou, Jeremy Ross, Eduardo Gotuzzo, Patricia Lelo, Helen Byakwaga, Oliver Ezechi, Jonathan Euvrard, Fernanda Maruri, Chad J. Achenbach, Jessica L. Castilho, on behalf of International epidemiology Databases to Evaluate AIDS (IeDEA)   +32 more
wiley   +1 more source

Systemic nutritional status and its dynamic changes as predictors of response to neoadjuvant immunotherapy in locally advanced MSS/pMMR colorectal cancer

Frontiers in Medicine
BackgroundPatients with locally advanced microsatellite-stable/mismatch repair–proficient (MSS/pMMR) colorectal cancer show heterogeneous responses to neoadjuvant immunotherapy, and effective predictive biomarkers are lacking. Systemic nutritional status
Haining Chen, Haining Chen, Zhiyuan Xia, Zhiyuan Xia, Yefu Shen, Yefu Shen, Xihua Xie, Xihua Xie, Ming Qiu, Ming Qiu, Minghui Lin, Minghui Lin, Shen Pang, Shen Pang, Dongchao Liu, Dongchao Liu, Wei Huang, Wei Huang, Sen Zhang, Sen Zhang   +19 more
doaj   +1 more source

HPV‐Related Cancers in Solid Organ Transplant Recipients: A Nationwide Danish Cohort Study

International Journal of Cancer, EarlyView.
Solid organ transplant recipients (SOTRs) face chronic immunosuppression, leaving them susceptible to viral infections. Of particular concern is persistent infection with human papillomavirus (HPV), which presents a significant cancer risk. This nationwide Danish cohort study estimated cancer risk in SOTRs using health registry data.
Signe Timm, Flemming Skjøth, Torben Frøstrup Hansen, Lars Henrik Jensen, Paw Christian Holdgaard, Lars Ulrik Fokdal, Torben Bjerregaard Larsen, Mette Moeller Soerensen   +7 more
wiley   +1 more source

Anal Cancer Risk Factors and Utilization of Anal Pap Smear Screening Among Transgender Persons

Papillomavirus Research, 2018
Objective: To identify risk factors for and understanding of anal cancer and associated screening tests among transgender persons. Methods: An anonymous survey was designed and distributed with SurveyMonkey.com to transgender persons recruited at health ...
Lydia A. Fein, MD MPH, Adriana Wong, BS, Isabella Rosa-Cunha, MD, Brian Slomovitz, MD, JoNell Potter, PhD   +4 more
doaj   +1 more source

Ultrasound–triggered tumor‐selective nitric oxide release enhances tumor penetration of antibody–conjugated nanomedicine

Interdisciplinary Medicine, EarlyView.
Ultrasound‐triggered nitric oxide release from S‐nitrosated hyaluronic acid (HA‐SNO) induces tumor vasodilation and disrupts the vascular barrier, potently enhancing the intratumoral penetration of antibody‐conjugated nanomedicines. Abstract The tumor vascular barrier restricts the penetration of antibody‐conjugated nanomedicine, severely limiting its ...
Xiaodong Wang, Ruifeng Duan, Xin Chen, Tongjun Liu, Zhilin Liu   +4 more
wiley   +1 more source

Cost‐effectiveness of screening for anal cancer using regular digital ano‐rectal examinations in men who have sex with men living with HIV

Journal of the International AIDS Society, 2016
Introduction Anal cancer in men who have sex with men (MSM) living with HIV is an important issue but there are no consistent guidelines for how to screen for this cancer.
Jason J Ong, Christopher K Fairley, Susan Carroll, Sandra Walker, Marcus Chen, Tim Read, Andrew Grulich, Catriona Bradshaw, John Kaldor, Philip Clarke   +9 more
doaj   +1 more source