Results 51 to 60 of about 3,204,753 (287)

Age‐Dependent Prognostic Significance of Preoperative Transthyretin After Curative Resection for Stage I–III Colorectal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Preoperative malnutrition and systemic inflammation are established determinants of adverse outcomes in colorectal cancer (CRC). Transthyretin (TTR), a rapid‐turnover hepatic protein, reflects both nutritional and inflammatory status; however, its clinical utility may be influenced by age‐ and sex‐related variability.
Ayane Kawata   +7 more
wiley   +1 more source

Arginase 2 Promotes Colorectal Cancer Metastasis via PI3K/AKT Pathway Activation and Regulates Tumor Immune Infiltration

open access: yesCancer Medicine
Background Colorectal cancer (CRC) is a leading cause of cancer‐related deaths, with metabolic reprogramming involved in its pathogenesis. Aberrant Arginase 2 (ARG2) expression is linked to malignant progression, but its role in CRC remains unclear ...
Yueyan Zhang   +9 more
doaj   +1 more source

Identification and predictive machine learning model construction of gut microbiota associated with carcinoembryonic antigens in colorectal cancer

open access: yesmSphere
Carcinoembryonic antigen (CEA) is a critical colorectal cancer (CRC) biomarker, but its mechanistic link to gut microbiota remains unclear. This study characterized gut microbiota differences between high-CEA (H-CEA) and low-CEA (L-CEA) CRC patients and ...
Yongzhi Wu   +12 more
doaj   +1 more source

Essential Updates 2024–2026: Advances in Colorectal Cancer Surgery

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Surgical innovation in colorectal cancer is increasingly judged not by technical feasibility alone, but by whether it improves oncological outcomes, preserves function, reduces morbidity, or makes difficult procedures more reproducible. This structured narrative review examines major surgical studies published from January 2024 through July ...
Hiroyasu Kagawa, Yusuke Kinugasa
wiley   +1 more source

Anal Cancer : A Review

open access: yesInternational Journal of Health Sciences, 2012
Anal cancer accounts for only 1.5% of gastrointestinal malignancies but this disease has shown a steady increase in incidence particularly in HIV positive males. The understanding of pathophysiology and treatment of anal cancer has changed radically over last thirty years.
Sajad Ahmad, Salati, Azzam, Al Kadi
openaire   +2 more sources

Prognostic Impact of Circumferential Resection Margin in Minimally Invasive Surgery for Locally Advanced Rectal Cancer: A Multicenter Prospective Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This multicenter prospective study provides the first Japanese evidence that circumferential resection margin positivity after minimally invasive surgery is associated with poorer long‐term outcomes in locally advanced rectal cancer. As the cohort predominantly included patients treated with upfront surgery, these findings provide important evidence to
Atsushi Hamabe   +19 more
wiley   +1 more source

Essential Updates in the Surgical Management of Inflammatory Bowel Disease: Current Topics From 2024 to Mid‐2026

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Inflammatory bowel disease management has undergone a major transformation with the introduction of treat‐to‐target strategies and highly effective biologic and small‐molecule therapies. Although these advances have reduced the overall requirement for surgery, operative intervention remains essential for selected patients with ulcerative ...
Yoshiki Okita   +4 more
wiley   +1 more source

Long‐Term Stoma‐Free Outcomes After Diverting Stoma Closure Following Radiation‐Based Neoadjuvant Treatment for Rectal Cancer

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Long‐term stoma‐free outcomes after diverting stoma closure in patients who underwent sphincter‐preserving rectal cancer surgery with double‐stapling technique (DST) reconstruction following radiation‐based neoadjuvant treatment remain unclear.
Hidetaka Ichikawa   +7 more
wiley   +1 more source

Retraction Note: Nuclear factor of activated T cells 5 maintained by Hotair suppression of miR-568 upregulates S100 calcium binding protein A4 to promote breast cancer metastasis

open access: yesBreast Cancer Research, 2018
The authors are retracting this article [1] after an investigation by the Ethics Committee of the Fourth Military Medical University (Xi’an, Shaanxi, China) of the following concerns that had been raised with respect to two of the figures:
Jun-Tang Li   +13 more
doaj   +1 more source

Exploring Symptom Domains of Postoperative Bowel Dysfunction by Integrating LARS and Wexner Scores: A Longitudinal Factor‐Analytic Study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Item‐level factor analysis of the LARS and Wexner scores in 320 patients undergoing sphincter‐preserving rectal resection identified three distinct symptom domains: incontinence, urgency/clustering, and gas control. These domains had different clinical determinants: radiotherapy was associated with greater severity of both incontinence and urgency ...
Yoshiko Matsumoto   +8 more
wiley   +1 more source

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