Results 111 to 120 of about 395,234 (289)

Oxaliplatin‐induced neuropathy after total neoadjuvant therapy for rectal cancer: Dose–response relationship and impact on quality of life

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Oxaliplatin serves a key role in the treatment of rectal cancer, though it is a significant cause of chemotherapy‐induced peripheral neuropathy. As total neoadjuvant therapy, in which all therapy is given before surgery, has become more common, understanding neuropathy has grown increasingly important. This study examined neuropathy and its
Georg W. Wurschi   +29 more
wiley   +1 more source

Understanding Autistic Young Adults' Perceptions and Experiences of Traumatic and Stressful Events

open access: yesJournal of Clinical Psychology, Volume 81, Issue 6, Page 445-461, June 2025.
ABSTRACT Objectives The aim of this study was to explore how young autistic adults experience and respond to stressful life events, and the relationship between autistic characteristics and symptoms of stress associated with these events. Methods Using an exploratory sequential mixed‐methods approach, an online qualitative survey was first administered
Alliyza Lim, Robyn L. Young
wiley   +1 more source

Anal Cancer Risk Factors and Utilization of Anal Pap Smear Screening Among Transgender Persons

open access: yesPapillomavirus Research, 2018
Objective: To identify risk factors for and understanding of anal cancer and associated screening tests among transgender persons. Methods: An anonymous survey was designed and distributed with SurveyMonkey.com to transgender persons recruited at health ...
Lydia A. Fein, MD MPH   +4 more
doaj   +1 more source

Oral rehydration solution for the management of fluid and electrolyte disturbances in patients with an ileostomy: A scoping review

open access: yesJournal of Parenteral and Enteral Nutrition, EarlyView.
Abstract Ileostomy creation is common among patients with colorectal cancer, diverticulitis, and inflammatory bowel disease. Surgical removal or diversion of the colon can result in nutrition complications, most notably dehydration—a leading cause of hospital readmission—and increased risk of kidney injury.
Austin J. Hoeg   +9 more
wiley   +1 more source

Cost‐effectiveness of screening for anal cancer using regular digital ano‐rectal examinations in men who have sex with men living with HIV

open access: yesJournal of the International AIDS Society, 2016
Introduction Anal cancer in men who have sex with men (MSM) living with HIV is an important issue but there are no consistent guidelines for how to screen for this cancer.
Jason J Ong   +9 more
doaj   +1 more source

Lower Gastrointestinal Bleeding Due to Multiple Polyps in Ileum [PDF]

open access: yes, 2002
The causes of lower gastrointestinal bleeding (hematochezia) are amyloidosis, anal fissure, angiodysplastic lesions, coagulation disorder, colitis, colon cancer, colorectal polyps, Crohn's disease, diverticulitis, haemorrhoids, etc.
Abdullah, M. (Murdani)   +4 more
core  

Tumour-infiltrating lymphocyte scores effectively stratify outcomes over and above p16 post chemo-radiotherapy in anal cancer

open access: yes
Background: The majority (90%) of anal cancers are human papillomavirus (HPV)-driven, identified using immunochemistry for p16. Compared with HPV? patients, those with HPV+ disease generally show improved survival, although relapse rates around 25 ...
Bailey, Charles   +7 more
core   +1 more source

Mass spectrometry imaging of N‐linked glycans: Fundamentals and recent advances

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract With implications in several medical conditions, N‐linked glycosylation is one of the most important posttranslation modifications present in all living organisms. Due to their nontemplate synthesis, glycan structures are extraordinarily complex and require multiple analytical techniques for complete structural elucidation.
Tana V. Palomino, David C. Muddiman
wiley   +1 more source

Should We Consider Sacral Nerve Stimulation as a Treatment for Neurogenic Lower Urinary Tract Dysfunction? ICI‐RS 2025

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Aims To explore the boundary of clinical use of sacral nerve stimulation (SNS) in neurogenic lower urinary tract dysfunction (NLUTD), identifying barriers to approval and early‐impact research questions. Methods This review is derived from a proposal discussion at the International Consultation on Incontinence‐Research Society in Bristol in ...
Marcus J. Drake   +6 more
wiley   +1 more source

Design, Synthesis, Cytotoxicity Assessment, and Molecular Docking of Novel Triazolopyrimidines as Potent Cyclin‐Dependent Kinase 4 Inhibitors

open access: yesChemistryOpen, EarlyView.
A novel series of 1,5‐dihydro‐[1,2,4]triazolo[4,3‐a]pyrimidines (5a–g) is synthesized and evaluated as potential CDK4 inhibitors. Compounds 5c and 5d exhibit strong cytotoxicity toward HepG2 and MCF‐7 cells with IC50 ≈ 1–2 µM, comparable to doxorubicin.
Tariq Z. Abolibda   +7 more
wiley   +1 more source

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