Results 11 to 20 of about 353,256 (314)
Optimization of Influential Variables in the Development of Buprenorphine and Bupivacaine Loaded Invasome for Dermal Delivery [PDF]
Purpose: Hydrophilic drugs are extensively applied in clinical applications. Inadequate dermal penetration of these drugs is a great challenge. Incorporation of drugs into nano-carrier systems overcomes lower penetration drawbacks.
Soraya Babaie+5 more
doaj +1 more source
Spiral Computed Tomography with Phytocomposition as a Diagnostic Tool for Adhesive Intestinal Obstruction [PDF]
Background: Adhesive intestinal obstruction is a common and potentially lethal complication after surgical interventions in the abdomen. Radiologic imaging is the main diagnostic method.
F Mufazalov+5 more
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Senna bicapsularis is an important medicinal plant that has been traditionally used as a purgative and muscle relaxant as well as for the treatment of pain.
Fahad A. Alhumaydhi
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Tongue hemangioma is a rare case of vascular tumors that causes symptoms such as pain, bleeding, difficulty in chewing, speaking, and breathing. We report a case of an oral lobular capillary hemangioma on the dorsal surface of the tongue treated with ...
Susan Susan+2 more
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Improvements in Intractable Lumbar and Lower-Extremity Symptoms after Systemic Administration of Tocilizumab, an Anti-interleukin-6 Receptor Antibody [PDF]
Study Design Prospective cohort study (open-label, single-arm, and non-blinded). Purpose This study aims to determine the effects of systemic administration of tocilizumab, an anti-interleukin-6 (IL-6) receptor antibody on refractory low back pain and ...
Takeshi Sainoh+34 more
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Analgesic Effect of Acetaminophen: A Review of Known and Novel Mechanisms of Action
Acetaminophen is one of the most commonly used analgesic agents for treating acute and chronic pain. However, its metabolism is complex, and its analgesic mechanisms have not been completely understood.
Nobuko Ohashi, T. Kohno
semanticscholar +1 more source
FigureĀ 1 caption was processed and published incorrectly. The correct caption should read as follows:
Martina Rekatsina+5 more
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Pathophysiologic Approach to Pain Therapy for Complex Pain Entities: A Narrative Review
Pain management is challenging for both clinicians and patients. In fact, pain patients are frequently undertreated or even completely untreated. Optimal treatment is based on targeting the underlying mechanisms of pain and tailoring the management ...
Martina Rekatsina+5 more
doaj +1 more source
The Modified WHO Analgesic Ladder: Is It Appropriate for Chronic Non-Cancer Pain?
Introduction From 1986, the World Health Organization (WHO) analgesic ladder has been used as the simple and valuable pain-relieving guidance in the pharmaceutical pain management, however, with the development of medical history, notions about pain ...
Juan Yang+4 more
semanticscholar +1 more source
A review of the mechanism of the central analgesic effect of lidocaine
Lidocaine, as the only local anesthetic approved for intravenous administration in the clinic, can relieve neuropathic pain, hyperalgesia, and complex regional pain syndrome. Intravenous injection of lidocaine during surgery is considered as an effective
Xi Yang+4 more
semanticscholar +1 more source