Results 11 to 20 of about 353,256 (314)

Optimization of Influential Variables in the Development of Buprenorphine and Bupivacaine Loaded Invasome for Dermal Delivery [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2021
Purpose: Hydrophilic drugs are extensively applied in clinical applications. Inadequate dermal penetration of these drugs is a great challenge. Incorporation of drugs into nano-carrier systems overcomes lower penetration drawbacks.
Soraya Babaie   +5 more
doaj   +1 more source

Spiral Computed Tomography with Phytocomposition as a Diagnostic Tool for Adhesive Intestinal Obstruction [PDF]

open access: yesJournal of Biomedical Physics and Engineering, 2020
Background: Adhesive intestinal obstruction is a common and potentially lethal complication after surgical interventions in the abdomen. Radiologic imaging is the main diagnostic method.
F Mufazalov   +5 more
doaj   +1 more source

In vivo analgesic, muscle relaxant, sedative and toxicological studies of Senna bicapsularis (L.) Roxb

open access: yesJournal of Taibah University for Science, 2021
Senna bicapsularis is an important medicinal plant that has been traditionally used as a purgative and muscle relaxant as well as for the treatment of pain.
Fahad A. Alhumaydhi
doaj   +1 more source

Unusual presentation of oral hemangioma in tongue and the potential use of propolis as an adjunctive treatment

open access: yesClinical Case Reports, 2021
Tongue hemangioma is a rare case of vascular tumors that causes symptoms such as pain, bleeding, difficulty in chewing, speaking, and breathing. We report a case of an oral lobular capillary hemangioma on the dorsal surface of the tongue treated with ...
Susan Susan   +2 more
doaj   +1 more source

Improvements in Intractable Lumbar and Lower-Extremity Symptoms after Systemic Administration of Tocilizumab, an Anti-interleukin-6 Receptor Antibody [PDF]

open access: yesAsian Spine Journal, 2022
Study Design Prospective cohort study (open-label, single-arm, and non-blinded). Purpose This study aims to determine the effects of systemic administration of tocilizumab, an anti-interleukin-6 (IL-6) receptor antibody on refractory low back pain and ...
Takeshi Sainoh   +34 more
doaj   +1 more source

Analgesic Effect of Acetaminophen: A Review of Known and Novel Mechanisms of Action

open access: yesFrontiers in Pharmacology, 2020
Acetaminophen is one of the most commonly used analgesic agents for treating acute and chronic pain. However, its metabolism is complex, and its analgesic mechanisms have not been completely understood.
Nobuko Ohashi, T. Kohno
semanticscholar   +1 more source

Correction to: Pathophysiologic Approach to Pain Therapy for Complex Pain Entities: A Narrative Review

open access: yesPain and Therapy, 2020
FigureĀ 1 caption was processed and published incorrectly. The correct caption should read as follows:
Martina Rekatsina   +5 more
doaj   +1 more source

Pathophysiologic Approach to Pain Therapy for Complex Pain Entities: A Narrative Review

open access: yesPain and Therapy, 2020
Pain management is challenging for both clinicians and patients. In fact, pain patients are frequently undertreated or even completely untreated. Optimal treatment is based on targeting the underlying mechanisms of pain and tailoring the management ...
Martina Rekatsina   +5 more
doaj   +1 more source

The Modified WHO Analgesic Ladder: Is It Appropriate for Chronic Non-Cancer Pain?

open access: yesJournal of Pain Research, 2020
Introduction From 1986, the World Health Organization (WHO) analgesic ladder has been used as the simple and valuable pain-relieving guidance in the pharmaceutical pain management, however, with the development of medical history, notions about pain ...
Juan Yang   +4 more
semanticscholar   +1 more source

A review of the mechanism of the central analgesic effect of lidocaine

open access: yesMedicine, 2020
Lidocaine, as the only local anesthetic approved for intravenous administration in the clinic, can relieve neuropathic pain, hyperalgesia, and complex regional pain syndrome. Intravenous injection of lidocaine during surgery is considered as an effective
Xi Yang   +4 more
semanticscholar   +1 more source

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