Results 31 to 40 of about 455,946 (356)

Pharmacological evaluation of processed Cannabis leaves as a non sedative analgesic: The novel approach

open access: yesJournal of Ayurveda, 2021
Background: Ayurvedic pharmacopoeia records vivid indications of Cannabis (Bhanga) including its analgesic, sedative and intoxicant actions. For inhibition of intoxication, Ayurveda recommends certain processing (Shodhana) techniques for Cannabis.
Swagata Dilip Tavhare   +2 more
doaj   +1 more source

Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain. An observational analysis [PDF]

open access: yes, 2016
INTRODUCTION: Cancer-related pain has a severe negative impact on quality of life. Combination analgesic therapy with oxycodone and pregabalin is effective for treating neuropathic cancer pain.
Borghesi, Cristina   +6 more
core   +2 more sources

From Poison to Promise: The Evolution of Tetrodotoxin and Its Potential as a Therapeutic

open access: yesToxins, 2021
Tetrodotoxin (TTX) is a potent neurotoxin that was first identified in pufferfish but has since been isolated from an array of taxa that host TTX-producing bacteria.
Gary M. Bucciarelli   +5 more
doaj   +1 more source

Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain [PDF]

open access: yes, 2017
Background: L-acetylcarnitine, a drug marketed for the treatment of chronic pain, causes analgesia by epigenetically up-regulating type-2 metabotropic glutamate (mGlu2) receptors in the spinal cord.
Battaglia, Giuseppe   +10 more
core   +1 more source

In Vivo, In Vitro and In Silico Study of Cucurbita moschata Flower Extract: A Promising Source of Natural Analgesic, Anti-Inflammatory, and Antibacterial Agents

open access: yesMolecules, 2023
For thousands of years, medicinal plants have played a pivotal role in maintaining human health and improving the quality of human life. This study was designed to analyze the analgesic, anti-inflammatory, and antibacterial potentials of a hydro ...
Md. Rabiul Hossain   +8 more
doaj   +1 more source

Emergency Department Pain Management Following Implementation of a Geriatric Hip Fracture Program [PDF]

open access: yes, 2017
Introduction: Over 300,000 patients in the United States sustain low-trauma fragility hip fractures annually. Multidisciplinary geriatric fracture programs (GFP) including early, multimodal pain management reduce morbidity and mortality. Our overall goal
Casey, Scott D   +6 more
core   +4 more sources

Cerebral and cardiovascular effects of analgesic doses of ketamine during a target controlled general anesthesia: a prospective randomized study [PDF]

open access: yes, 2017
Introduction: Ketamine is increasingly being used in various pain settings. The purpose of this study was to assess the effect of an analgesic dose of ketamine in the bispectral index (BIS), spectral edge frequency (SEF-95), density spectral array (DSA),
Araujo, A. M.   +3 more
core   +1 more source

Benefits of thoracic epidural analgesia in patients undergoing an open posterior component separation for abdominal herniorrhaphy [PDF]

open access: yes, 2017
INTRODUCTION: The implementation of open posterior component separation (PCS) surgery has led to improved outcomes for complex hernias. While the PCS technique has been shown to decrease recurrence rates, and provide a feasible option to repair hernias ...
Sellers, Austin
core   +1 more source

Opioid Analgesics [PDF]

open access: yesMayo Clinic Proceedings, 2015
Chronic pain is an international health issue of immense importance that is influenced by both physical and psychological factors. Opioids are useful in treating chronic pain but have accompanying complications. It is important for clinicians to understand the basics of opioid pharmacology, the benefits and adverse effects of opioids, and related ...
Robert N, Jamison, Jianren, Mao
openaire   +2 more sources

Development and optimisation of novel oral formulation of an opioid analgesic using central composite design

open access: yesCogent Medicine, 2017
Introduction of matrix type sustained release systems were a breakthrough for novel oral drug delivery systems. Present research focuses on the development and evaluation of Fentanyl citrate sustained release formulations.
Meenal M. Rane, Amrita Bajaj
doaj   +1 more source

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