Results 81 to 90 of about 455,946 (356)

Electrosynthesis of Bioactive Chemicals, From Ions to Pharmaceuticals

Advanced Functional Materials, EarlyView.
This review discusses recent advances in electrosynthesis for biomedical and pharmaceutical applications. It covers key electrochemical materials enabling precise delivery of ions and small molecules for cellular modulation and disease treatment, alongside catalytic systems for pharmaceutical synthesis.
Gwangbin Lee, Sojin Kim, Myeongeun Lee, Kyoungsuk Jin, Jimin Park   +4 more
wiley   +1 more source

Butorphanol for Post-Operative Analgesia - A Comparative Clinical Study with Ketorolac [PDF]

, 2010
Introduction: Butorphanol, an opioid derivative has been shown to have, in addition to its analgesic properties, several other advantageous effects like antistressor, sedative and anti-shivering action.
Adappa, Karunakara, Kadam, Dinesh, Kadri, Rajani, Koteshwar, Reshma, Mohan, Prashanth, Shenoy, Sunil P, Tantry, Thrivikrama Padur, Vastrad, Nandish S   +7 more
core   +1 more source

Self‐Feeding of Engineered Tissues via Controlled Glucose Release Facilitates Survival and Vascularization of Living Implants

Advanced Functional Materials, EarlyView.
ABSTRACT Engineering living matter has great clinical potential to deliver functional replacement organs. However, clinical translation remains hampered by the current inability to maintain viability of clinically relevant‐sized constructs. During the pre‐vascular phase, implants rely on nutrient diffusion for survival, which is insufficient at ...
Melvin Gurian, Iris E. Allijn, Laura Veenendaal, Nicole Bassous, Su Ryon Shin, Jeroen Leijten   +5 more
wiley   +1 more source

Orbitofrontal Cortex in Chronic Analgesic-Overuse Headache

Pediatric Neurology Briefs, 2006
Glucose metabolism with 18-FDG PET in 16 chronic migraineurs (mean age 42.5 +/- 11 years) with analgesic overuse, before and 3 weeks after medication withdrawal, was compared to controls.
J Gordon Millichap
doaj   +1 more source

BU10038 as a safe opioid analgesic with fewer side-effects after systemic and intrathecal administration in primates [PDF]

, 2019
© 2019 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.Background: The marked increase in mis-use of prescription opioids has greatly affected our society. One potential solution is to develop improved analgesics which have
Cami-Kobeci, Gerta, Czoty, Paul W., DeLoid, Heather B., Ding, Huiping, Hsu, Fang Chi, Husbands, Stephen M., Kiguchi, Norikazu, Ko, Mei Chuan, Sukhtankar, Devki D., Toll, Lawrence   +9 more
core   +5 more sources

A Bioresorbable Neural Interface for On‐Demand Thermal Pain Block

Advanced Functional Materials, EarlyView.
Bioresorbable, implantable neural electronics provide dynamic, on‐demand thermal modulation of peripheral nerves for safe, drug‐free pain relief. A microscale thin‐film heater and temperature sensor embedded within biodegradable encapsulants enable precise temperature control via real‐time feedback.
Jeonghwan Park, Hak‐Young Ahn, Minho Seong, Taehoon Kim, Yulin Zhou, Yameng Xu, Jaehee Lee, Ritika Raj Menghani, Yujin Choi, Minsu Park, Nadir Muzaffar, Youngeun Lee, Seung Gi Seo, Jong Uk Kim, Sang Min Won, Jahyun Koo, Elena Aprea, Taeyeon Kim, Ying Yan, Matthew R. MacEwan, Wilson Z. Ray, Raudel Avila, Geumbee Lee, John A. Rogers   +23 more
wiley   +1 more source

Zingerone alleviates inflammatory pain by reducing the intrinsic excitability of anterior cingulate cortex neurons in a mice model

Frontiers in Pharmacology
BackgroundZingiber officinale Roscoe has been shown to possess analgesic properties. Zingerone (ZO), a bioactive compound derived from Zingiber officinale Roscoe, exhibits a range of pharmacological effects, including anti-inflammatory, anti-cancer ...
Yuanyuan Wang, Yuanyuan Wang, Yuanyuan Wang, Lang Dong, Lang Dong, Shu Han, Yuehan You, Mingrui Zhang, Bingjing Sun, Bingjing Sun, Hong Ni, Hong Ni, Rongjing Ge, Rongjing Ge, Jianhong Liu, Jianhong Liu, Jiandong Yu, Jiandong Yu, Jiandong Yu   +18 more
doaj   +1 more source

Analgesic and antiinflammatory activities of the aqueous root extract of Algerian Bunium incrassatum [PDF]

Archives of Biological Sciences
The present study was designed to evaluate the antioxidant, analgesic, and antiinflammatory activities of Bunium incrassatum aqueous extract (BIAE) from roots.
Amraoui Nacer, Boutefaha Zineddine, Belattar Noureddine, Arrar Lekhmici   +3 more
doaj   +1 more source

A Novel Sprayable Fibrinogen/Glycosaminoglycans/Collagen‐Based Bioink for Skin Wound Healing Applied by a Handheld Dual‐Head Airbrush

Advanced Healthcare Materials, EarlyView.
A dual‐head airbrush‐based spraying device, combined with a fibrinogen bioink enriched with glycosaminoglycans and collagen, enables the delivery of biomaterials and cells to promote wound healing. This system demonstrates effective skin regeneration in vitro and in vivo, with comparable results to autografts.
Paula Pleguezuelos‐Beltrán, Daniel Nieto‐García, Carlos Chocarro‐Wrona, Juan de Vicente, Patricia Gálvez‐Martín, José Manuel Entrena, Elena López‐Ruiz, Juan Antonio Marchal   +7 more
wiley   +1 more source

Use of Analgesics in Dentistry and Orthopedics: A Survey-based Study in India

Journal of Surgical Specialties and Rural Practice
Background: Pain is a significant health problem, and it is estimated that 1 in 5 adults suffers from pain, and even more alarmingly, 1 in 10 adults is diagnosed annually with chronic pain.
Ananda Kisor Pal, Chandra Sekhar Dannana, Shreedhar Archik, Vineet Avadhani, Sanjay Miglani, Akshay Uttam Desai, Neha Keswani   +6 more
doaj   +1 more source