Results 171 to 180 of about 225,759 (311)

Investigation of the Peripheral Analgesic Activity of Oxicams and Their Combinations with Caffeine. [PDF]

Turk J Pharm Sci, 2020
Syrova A, Lukyanova L, Kozub S, Zavada O, Levashova O, Shaposhnik V.   +5 more
europepmc   +1 more source

Optimization of the Purifying Process for Columbianetin-β-D-Glucopyranoside from Angelicae Pubescentis Radix and Evaluation of Its Analgesic Activity Using Hot Plate Test. [PDF]

Evid Based Complement Alternat Med, 2021
Zhang Y, Yang Y, Shang Y, Liang C, He J, Li J, Chang Y.   +6 more
europepmc   +1 more source

Efficacy and Safety of Guselkumab in Participants With Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of a Phase 3, Randomized, Placebo‐Controlled Study

Arthritis &Rheumatology, EarlyView.
Objective To evaluate the efficacy and safety of guselkumab, an interleukin‐23p19 subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor (TNF) inhibitor.
Alexis Ogdie, Joseph F. Merola, Philip J. Mease, Christopher T. Ritchlin, Jose U. Scher, Kimberly Parnell Lafferty, Daphne Chan, Soumya D. Chakravarty, Wayne Langholff, Yanli Wang, Jie Shao, Yevgeniy Krol, Alice B. Gottlieb   +12 more
wiley   +1 more source

The Potential Role of Synovial T Cell Infiltration Following Knee Joint Injury in Symptoms and Progression to Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Identification of osteoarthritis (OA)–specific synovial inflammatory pathways and their temporal relevance is critical for therapeutic targeting. We compared mononuclear inflammatory/immune cell responses following joint injury that does or does not lead to OA to define bona fide OA‐associated cellular events.
Babak Moradi, Miriam T. Jackson, Cindy C. Shu, Susan M. Smith, Margaret M. Smith, Sanaa Zaki, Hadrian Platzer, Nils Rosshirt, David Giangreco, Carla R. Scanzello, Christopher B. Little   +10 more
wiley   +1 more source

Methanol, ethyl acetate and n-hexane extracts of Tragia involucrata L. leaves exhibit anxiolytic, sedative and analgesic activity in Swiss albino mice. [PDF]

Heliyon, 2021
Islam MS, Sana S, Haque ME, Rahman SMM, Samad A, Al Noman A, Al Noman A, Alam R, Rana S, Meem RI, Mondol D, Islam MS, Islam MT, Mazumder K.   +13 more
europepmc   +1 more source

Nerve growth factor is sufficient to cause multiple osteoarthritis‐relevant pathological features in naïve murine knee joints

Arthritis &Rheumatology, Accepted Article.
Objective Nerve growth factor (NGF), a key mediator of pain, is increased in osteoarthritic (OA) joints. Antibodies against NGF show analgesic effects in painful knee OA, but clinical development was stopped due to side‐effects in the joints. Knowledge about the biological effects of NGF on joint tissues is limited.
Alia M. Obeidat, Michael D. Newton, Jun Li, Baofeng Hu, Shingo Ishihara, Lindsey Lammlin, Lucas M. Junginger, Easton C. Farrell, Lai Wang, Frank C. Ko, Richard J. Miller, Carla R. Scanzello, Tristan Maerz, Rachel E. Miller, Anne‐Marie Malfait   +14 more
wiley   +1 more source

Determinants of Difficult‐to‐Manage and Treatment‐Refractory Axial Spondyloarthritis: A Cross‐Sectional Analysis within a Longitudinal Cohort

Arthritis &Rheumatology, Accepted Article.
Objective To estimate the prevalence of difficult‐to‐manage (D2M) and treatment‐refractory (TR) axSpA and to identify factors associated with D2M/TR disease in a longitudinal cohort. Methods We performed a cross‐sectional analysis on data from the Schroeder Arthritis Institute Spondylitis Program cohort.
Patricia Remalante‐Rayco, Laura Passalent, Tina Chim, Hannah Vijayan, Manal Alnasser, Zeynep Baskurt, Robert D. Inman, Nigil Haroon, Denis Poddubnyy   +8 more
wiley   +1 more source

A novel nerve block and anatomy workshop for emergency medicine residents: A pilot study

Anatomical Sciences Education, EarlyView.
Abstract Construct a workshop for emergency medicine (EM) residents to learn ultrasound‐guided regional anesthesia (UGRA) procedures and build confidence in performing those procedures. Use pre‐ and post‐workshop knowledge and confidence surveys to determine workshop effectiveness.
Geoffery D. Fernquist, Derek Harmon, Lauren D. Branditz, Andrew Kendle, Melissa M. Quinn   +4 more
wiley   +1 more source

Cannabidiol-based lipid nanocarriers with analgesic activity. [PDF]

Sci Rep
de Oliveira Sato A, Goulart JPT, Rodrigues TS, Ueira-Vieira C, Bastos LM, Sommerfeld S, Fonseca BB, de Morais Ribeiro LN.   +7 more
europepmc   +1 more source

Bowtie Technique for Arthroscopic Hip Inversion Labral Repair

Arthroscopy Techniques, EarlyView.
Abstract Various suture techniques for arthroscopic hip labral repair have been described to address labral pathology. However, optimal restoration of the labral suction seal relies on proper tension and control of the labral tissue during the repair.
Mathew Park, Spencer Sims, Tyler Bilden, Grace Peterson, Travis Menge   +4 more
wiley   +1 more source