The effects of clonidine and yohimbine in the tail flick and hot plate tests in the naked mole rat (Heterocephalus glaber) [PDF]
BMC Research Notes, 2021 Objective The naked mole rat (NMR) (Heterocephalus glaber) is increasingly considered an important biomedical research model for various conditions like hypoxic brain injury, cancer and nociception.
R. M. Mwobobia +2 more
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Antinociceptive Effects of Cannabichromene (CBC) in Mice: Insights from von Frey, Tail-Flick, Formalin, and Acetone Tests [PDF]
Biomedicines, 2023 Cannabis sativa contains minor cannabinoids that have potential therapeutic value in pain management. However, detailed experimental evidence for the antinociceptive effects of many of these minor cannabinoids remains lacking.
Wesley M. Raup-Konsavage +5 more
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Comparison of electroencephalographic changes in response to acute electrical and thermal stimuli with the tail flick and hot plate test in rats administered with opiorphin [PDF]
BMC Neurology, 2018 Background The objective of this study was to compare the changes in the electroencephalogram (EEG) in response to noxious stimuli with tail flick and hot plate responses of rats administered opiorphin.
Preet Singh +6 more
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Tail Flick Modification of Orexin-A Induced Changes of Electrophysiological Parameters in The Rostral Ventromedial Medulla [PDF]
Cell Journal, 2014 Objective: It is well known that intracerebroventricular (ICV) and supraspinal injections of orexin-A elicit analgesia, but the mechanism(s) of action remains unidentified.
Hassan Azhdari-Zarmehri +3 more
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Analgesic Activity of Aqueous Extract of Solanum Xanthocarpum Berries (SXB) in Animal Models [PDF]
International Journal of Scientific Research in Dental and Medical Sciences, 2021 Background and aim: Traditional medicines can be considered a reliable source of new drugs as they are safe, dependable, and cost-effective compared to synthetic drugs.
Tarinita Leisangthem +3 more
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ANTI-NOCICEPTIVE EFFECT OF RHIZOME OF ZINGIBER OFFICINALE(GINGER),APPLE VINGER AND THEIR COMBINATION ON ANIMAL MODELS OF PAIN IN LABORATORY RATS. [PDF]
Basrah Journal of Veterinary Research, 2008 This study was performed to investigate the anti-nociceptive effect of aqueous extract of Zingiber officinale rhizomes by three animal models of pain (hot plate test , tail flick and formalin test.
Nowfel H.Jassim
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Better binding with a flick of the tail [PDF]
The Journal of Cell Biology, 2008 ![Graphic][1] When Ran binds to RCC1 (right), FRET (yellows and reds) decreases as chromatin binding increases. When RCC1's tail gets between it and chromatin, it gets a little help from its partner, Ran, to move the tail aside, according to [Hao and Macara][2].
Robinson, Richard, Williams, Ruth
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Tail-flick-est – aspects use in pharmacological researches
Фармацевтичний журнал, 2018 The adequate assessment of anti-nociceptive activity is important. This is necessary for development of new analgesics that exceed effectiveness and/or safety of existing analgesics, fundamental research, study specifics pharmacodynamics of known ...
T. V. Kava, O. E. Yadlovskiy
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The Role of Parabrachial GABAA Receptors in Pain Modulation in Rats [PDF]
Journal of Fasa University of Medical Sciences, 2013 Background & Objective: The parabrachial nucleus is a critical link in the transmission of short latency nociceptive information to midbrain neurons.
kazem javanmardi +6 more
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Heliyon, 2022 This investigation aimed to assess the anti-inflammatory and analgesic effects of Cedrus libani and Pinus brutia leaves. The anti-inflammatory property was evaluated by Human Red Blood Cells (HRBC) membrane stabilization assay and Albumin denaturation ...
Lina Karrat +2 more
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