Results 11 to 20 of about 257,409 (278)

The Role of NMDARs Ligands on Antinociceptive Effects of Pregabalin in the Tail Flick Test. [PDF]

Anesth Pain Med, 2015
BACKGROUND: Pregabalin as a new anticonvulsant has been used in different pain treatments. OBJECTIVES: The aim of this study was to investigate the role of N-methyl-D-aspartate (NMDA) ligands in antinociceptive effect of pregabalin in mice using tail ...
Meymandi MS, Keyhanfar F, Yazdanpanah O, Heravi G.   +3 more
europepmc   +2 more sources

Perbandingan Metode Tail-Immersion dan Tail Flick terhadap Uji Efek Analgesik Pethidin HCI pada Mencit Betina [PDF]

, 2004
Dalam penelitian ini dilakukan perbandingan metode Tail Immersion dan Tail Flick terhadap uji efek analgesik Pethidin HCI pada mencit betina (Mus musculus) galur Swiss Webster.
Chandra, Melinda
core   +2 more sources

INVESTIGATION OF TOLERANCE TO THE ANTINOCICEPTIVE ACTION OF INTRATHECAL MORPHINE (TAIL FLICK, HOT PLATE).

, 1985
INVESTIGATION OF TOLERANCE TO THE ANTINOCICEPTIVE ACTION OF INTRATHECAL MORPHINE (TAIL FLICK, HOT PLATE)
CORINNE BLYTHE. TYLER (7983671)
core   +4 more sources

Thermal latency studies in opiate-treated mice

Journal of Pharmacy and Bioallied Sciences, 2014
Background: The change in the reaction time of a tail or paw exposed to a thermal stimulus is a measure of nociceptive activity in laboratory animals. Tail-flick and plantar thermal sensitivity (Hargreaves) tests are non-invasive, minimize stress, and ...
Noam Schildhaus, Eliana Trink, Chirs Polson, Louis DeTolla, Betty M Tyler, George I Jallo, Sino Tok, Michael Guarnieri   +7 more
doaj   +1 more source

A Flick of the Tail Keeps the Circadian Clock in Line [PDF]

Molecular Cell, 2017
Circadian clocks signal and adapt to an ever-changing world by juggling a panoply of transcriptional and post-translational modifications. In this issue of Molecular Cell, Gustafson et al. (2017) report an additional requirement for accurate timekeeping, a cis/trans conformational flicker in the transcriptional activation domain of the core clock ...
Rajesh, Narasimamurthy, David M, Virshup
openaire   +2 more sources

Acute phenobarbital administration induces hyperalgesia: pharmacological evidence for the involvement of supraspinal GABA-A receptors

Brazilian Journal of Medical and Biological Research, 2001
The aim of the present study was to determine if phenobarbital affects the nociception threshold. Systemic (1-20 mg/kg) phenobarbital administration dose dependently induced hyperalgesia in the tail-flick, hot-plate and formalin tests in rats and in the ...
C.M. Yokoro, S.M.S. Pesquero, R.M.M. Turchetti-Maia, J.N. Francischi, M.A.K.F. Tatsuo   +4 more
doaj   +1 more source

Co-administration of Pregabalin and Curcumin Synergistically Decreases Pain-Like Behaviors in Acute Nociceptive Pain Murine Models

Molecules, 2020
Analgesic drugs in a combination-form can achieve greater efficacy with lesser side effects compared to either drug alone. The combination of drugs acting at different targets or mechanisms of action has been recognized as an alternative approach for ...
Sarinee Leksiri, Hasriadi, Peththa Wadu Dasuni Wasana, Opa Vajragupta, Pornchai Rojsitthisak, Pasarapa Towiwat   +5 more
doaj   +1 more source

Hyperalgesic effect induced by barbiturates, midazolam and ethanol: pharmacological evidence for GABA-A receptor involvement

Brazilian Journal of Medical and Biological Research, 1997
The involvement of GABA-A receptors in the control of nociception was studied using the tail-flick test in rats. Non-hypnotic doses of the barbiturates phenobarbital (5-50 mg/kg), pentobarbital (17-33 mg/kg), and thiopental (7.5-30 mg/kg), of the ...
M.A.K.F. Tatsuo, C.M. Yokoro, J.V. Salgado, S.M.S. Pesquero, M.A.P. Santana, J.N. Francischi   +5 more
doaj   +1 more source

Alteration in behavior of rat after chronic exposure to acetamiprid [PDF]

Veterinary World, 2019
Background and Aim: Acetamiprid is a chemical of neonicotinoid group which binds with nicotinic acetylcholine receptor (nAChR) and alters the brain function.
Samiran Mondal, Saktipada Pradhan, Sunit K. Mukhopadhayay   +2 more
doaj   +1 more source

Antinociceptive potency of aminoglycoside antibiotics and magnesium chloride: a comparative study on models of phasic and incisional pain in rats

Brazilian Journal of Medical and Biological Research, 2002
A close relationship exists between calcium concentration in the central nervous system and nociceptive processing. Aminoglycoside antibiotics and magnesium interact with N- and P/Q-type voltage-operated calcium channels.
W.A. Prado, E.B. Machado Filho
doaj   +1 more source